Effects of acute ammonia toxicity on oxidative stress, immune response and apoptosis of juvenile yellow catfish Pelteobagrus fulvidraco and the mitigation of exogenous taurine

Zhang, Muzi; Li, Ming; Wang, Rixin; Qian, Yunxia

doi:10.1016/j.fsi.2018.05.036

Cited by 172 publications

(80 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…GR is an important indicator for evaluating the degree of oxidative stress [53]. Figure 2 showed that the GR levels increased first, and then decreased following transport time, reaching a peak level at 10 h, which was similar to cortisol and HSP70.…”

Section: Effect Of Temperature On Antioxidant Enzyme Of Tiger Groupermentioning

confidence: 80%

Effects of Ascorbic Acid and β-1,3-Glucan on Survival, Physiological Response and Flesh Quality of Cultured Tiger Grouper (Epinephelus fuscoguttatus) during Simulated Transport in Water

Wang

Cao

et al. 2020

Biology

View full text Add to dashboard Cite

Transport in water is the most common method for achieving high survival rates when transporting cultured fish in China; yet, transport success relies on proper water quality and conditions. This research was designed to explore the effects of ascorbic acid and β-1,3-glucan on survival, physiological responses, and flesh quality of farmed tiger grouper (Epinephelus fuscoguttatus) during simulated transport. The transport water temperature for live tiger grouper was 15 °C, which had the highest survival rate, the lowest stress response, and metabolic rate, and this will reduce the susceptibility to diseases. It is stated that β-1,3-glucan influences the changes of cortisol content, heat shock protein 70, IL-1β, and IgM transcription levels during simulated transport. Rather than using ascorbic acid alone (the A-group), β-1,3-glucan (3.2 mg/L) in the presence of ascorbic acid (25 mg/L) can effectively reduce the increase of transport-induced serum cortisol content, heat shock protein 70, and IL-1β, but stimulated IgM. 25 mg/L ascorbic acid and 3.2 mg/L β-1,3-glucan had no obvious effect on the nutritional indexes and flavor of live tiger grouper; however, these can effectively reduce the stress response, improve the innate immune activity, and ensure a higher survival rate.

show abstract

Section: Effect Of Temperature On Antioxidant Enzyme Of Tiger Groupermentioning

confidence: 80%

Effects of Ascorbic Acid and β-1,3-Glucan on Survival, Physiological Response and Flesh Quality of Cultured Tiger Grouper (Epinephelus fuscoguttatus) during Simulated Transport in Water

Wang

Cao

et al. 2020

Biology

View full text Add to dashboard Cite

show abstract

“…Superoxide dismutase (SOD), a key antioxidant enzyme, constitutes an important part of the first‐line antioxidative defence system that eliminates ROS from cells (Duan et al, 2016). High ammonia exposure or nitrite stress could trigger the overproduction of ROS to induce oxidative stress in juvenile yellow catfish and L. vannamei (Duan et al, 2018b; Zhang et al, 2018b), thereby increasing the level of malondialdehyde (MDA) (Duan et al, 2018b). Thus, levels of MDA and antioxidant enzymes serve as important indicators used for evaluating the health status of marine organisms (Bebianno et al, 2005).…”

Section: Effects Of Ammonia Stress On Shrimp Physiology and Biochemistrymentioning

confidence: 99%

Effects of ammonia on shrimp physiology and immunity: a review

Zhao

Yao

et al. 2020

Reviews in Aquaculture

View full text Add to dashboard Cite

The rapid expansion in shrimp farming comes with problems such as inadequate culture technology, disease outbreak, water pollution and other environmental degradation‐related problems. Prominent among these is the level of ammonia, which has been rising steadily in the last couple of years, mainly due to farming practices and other anthropogenic activities, and therefore has had consequent effects on marine life, especially shrimp. While optimal ammonia levels are a good source of nitrogen for marine phytoplankton that increases the level of dissolved oxygen in water as well serves as food for shrimp, high levels of ammonia are harmful to shrimp. When shrimp pond ammonia levels go beyond the tolerance limits, it inhibits chitinase expression, moulting, growth, phenoloxidase and haemolymph antimicrobial activity, thereby attenuating shrimp innate immune response. In this review, we bring together recent information on the effects of ammonia stress on the growth, physiology, biochemistry, ammonia‐metabolizing enzymes and immunity of shrimp. We also propose areas of research that can be explored in the breeding of new ammonia‐tolerant and disease‐resistant shrimp with robust immune and/or physiological systems that could withstand environmental stress and pathogens.

show abstract

“…induced cell death Zhang et al, 2018). Apoptosis induced by ammonia is regulated through a variety of signaling pathways, such as interruption of intracellular calcium ion (Ca 2+ ) homeostasis and activation of the p53 pathway .…”

Section: Figure 4 | H 2 S Prevents Nhmentioning

confidence: 99%

Hydrogen Sulfide Protects Against Ammonia-Induced Neurotoxicity Through Activation of Nrf2/ARE Signaling in Astrocytic Model of Hepatic Encephalopathy

Jin

Chen

et al. 2020

Front. Cell. Neurosci.

View full text Add to dashboard Cite

Objective: Hepatic encephalopathy (HE) characterized by neuropsychiatric abnormalities is a major complication of cirrhosis with high mortality. However, the pathogenesis of HE has not been fully elucidated. This study aimed to determine endogenous hydrogen sulfide (H 2 S) in the blood of HE patients and investigate the role of H 2 S in an astrocytic model of HE. Methods: Patients with and without HE were recruited to determine plasma H 2 S levels and blood microbial 16S rRNA gene. Rat astrocytes were employed as a model of HE by treatment of NH 4 Cl. Exogenous H 2 S was preadded. Cell viability was measured by Cell Counting Kit-8 (CCK-8) assay, and cell death was evaluated by lactate dehydrogenase (LDH) release. Apoptosis was determined by Hoechst 33342/Propidium Iodide (PI) Double Staining and Western blot analysis of apoptosis-related protein expression. Intracellular reactive oxygen species (ROS) levels were assessed by flow cytometer. Expressions of Nrf2 and its downstream regulated genes were examined by immunofluorescence staining and Western blot, respectively. Nrf2 gene knockdown was performed by antisense shRNA of Nrf2 gene. Results: There was a significant decrease in H 2 S levels in cirrhotic patients with HE compared with without HE. Blood microbiota analyses revealed that certain strains associated with H 2 S production were negatively correlated with HE. In vitro, H 2 S markedly attenuated NH 4 Cl-induced cytotoxicity, oxidative stress, and apoptosis. This effect was mediated by Nrf2/ARE signaling, and knockdown of Nrf2 expression abolished the antagonistic effect of H 2 S on NH 4 Cl-induced neurotoxicity in astrocytes. Conclusion: Levels of H 2 S and bacteria associated with H 2 S production are decreased in HE, and H 2 S functions as the neuroprotector against NH 4 Cl-induced HE by activating Nrf2/ARE signaling of astrocytes.

show abstract

Effects of acute ammonia toxicity on oxidative stress, immune response and apoptosis of juvenile yellow catfish Pelteobagrus fulvidraco and the mitigation of exogenous taurine

Cited by 172 publications

References 53 publications

Effects of Ascorbic Acid and β-1,3-Glucan on Survival, Physiological Response and Flesh Quality of Cultured Tiger Grouper (Epinephelus fuscoguttatus) during Simulated Transport in Water

Effects of Ascorbic Acid and β-1,3-Glucan on Survival, Physiological Response and Flesh Quality of Cultured Tiger Grouper (Epinephelus fuscoguttatus) during Simulated Transport in Water

Effects of ammonia on shrimp physiology and immunity: a review

Hydrogen Sulfide Protects Against Ammonia-Induced Neurotoxicity Through Activation of Nrf2/ARE Signaling in Astrocytic Model of Hepatic Encephalopathy

Contact Info

Product

Resources

About