Effects of a Randomized Controlled Trial of Transcendental Meditation on Components of the Metabolic Syndrome in Subjects With Coronary Heart Disease

Paul-Labrador, Maura; Polk, Donna M.; Dwyer, James H.; Velasquez, Ivan; Nidich, Sanford; Rainforth, Maxwell; Schneider, Robert; Merz, C. Noel Bairey

doi:10.1001/archinte.166.11.1218

Cited by 205 publications

(153 citation statements)

References 45 publications

Supporting

Mentioning

140

Contrasting

Unclassified

Order By: Relevance

“…We believe that this is the same mechanism that acts reducing BP values while the subjects are listening to calm music and respiration rates are unaltered. Our findings regarding BP reductions during calm music are similar to other studies involving other interventions as meditation 20 and can be explained by the subjects relaxation over time, 1 as observed in other studies.…”

Section: Discussionsupporting

confidence: 91%

Sympathetic nerve activity is decreased during device-guided slow breathing

et al. 2010

View full text Add to dashboard Cite

It is known that slow breathing (o10 breaths min -1 ) reduces blood pressure (BP), but the mechanisms involved in this phenomenon are not completely clear. The aim of this study was to evaluate the acute responses of the muscle sympathetic nerve activity, BP and heart rate (HR), using device-guided slow breathing (breathe with interactive music (BIM)) or calm music. In all, 27 treated mild hypertensives were enrolled. Muscle sympathetic nerve activity, BP and HR were measured for 5 min before the use of the device (n¼14) or while subjects listened to calm music (n¼13), it was measured again for 15 min while in use and finally, 5 min after the interventions. BIM device reduced respiratory rate from 16 ± 3 beats per minute (b.p.m) to 5.5 ± 1.8 b.p.m (Po0.05), calm music did not affect this variable. Both interventions reduced systolic (À6 and À4 mm Hg for both) and diastolic BPs (À4 mm Hg and À3 mm Hg, respectively) and did not affect the HR (À1 and À2 b.p.m respectively). Only the BIM device reduced the sympathetic nerve activity of the sample (À8 bursts min -1 ). In conclusion, both device-guided slow breathing and listening to calm music have decreased BP but only the device-guided slow breathing was able to reduce the peripheral sympathetic nerve activity.

show abstract

Section: Discussionsupporting

confidence: 91%

Sympathetic nerve activity is decreased during device-guided slow breathing

et al. 2010

View full text Add to dashboard Cite

show abstract

“…Yoga is the most common form of relaxation technique adopted in Indian culture since ancient time. 12 Among the yoga based relaxation techniques, deep relaxation technique (DRT), supine rest (SR) or shavasan, cyclic meditation (CM) has become topic of research focus, studied by several investigators in both health& diseased condition [13][14][15][16][17][18][19][20] . SR has been described as relaxation & awareness on the border between sleep and wakefulness, allowing contact with the sub conscious and unconscious mind 13 .…”

Section: Introductionmentioning

confidence: 99%

“…Various investigators investigated the effect of relaxation response on cardiac autonomic nerve function by assessment of heart rate variability (HRV) which is more sensitive, non invasive procedure to quantify cardiac parasympathetic and sympathetic activity 18,[20][21][22][23] .…”

Section: Introductionmentioning

confidence: 99%

Effect of supine rest on cardiac autonomic tone in type 2 diabetes mellitus

Rahman

Ferdousi

2018

J Bangladesh Soc Physiol

View full text Add to dashboard Cite

Background: Autonomic nerve dysfunction has been noted in type 2 diabetes mellitus (T2DM). Regular practice of supine rest (SR) may cause improvement of this impaired autonomic nerve function.Objective: To observe the effect of SR on the autonomic nerve activity by analysis of heart rate variability (HRV) in patients with T2DM.Methods: This prospective interventional study was carried out in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU)during 2016 on 30 female diagnosed T2DM patients aged 50-55 years with duration of diabetes of 5-10 years. They performed SR (20 minutes twice daily) for 3 months. The diagnosed patients were selected from the Out Patient Department of Endocrinology, BSMMU, Dhaka. Thirty age matched apparently healthy females who did not perform regular SR, were control. To assess the cardiac autonomic nerve function, HRV parameters of all subjects were recorded by PowerLab. HRV data of all subjects were collected at baseline and also after 3 months follow-up. In addition, urinary level of Vanillyl Mandelic acid (VMA) of all subjects were measured at baseline and at post intervention period for patients. For statistical analysis, paired and independent sample t-tests were done, as applicable.Results: The pre-intervention values of LF normalized unit (LF nu), LF/HF ratio(p<0.01) and urinary VMA were significantly higher(p <0.001) and HF normalized unit (HF nu) was significantly (p<0.01)lower in all diabetic patients compared to control. The post-intervention data showed LF nu, LF/HF ratio and urinary VMA were reduced and HF nu was increased but these changes were not statistically significant (p> 0.05) in diabetic patients.Conclusion: This study concluded that parasympathetic activity decreased, increased sympathetic activity with higher sympathovagal balance indicating autonomic dysfunction in patients with T2DM, which was shown with trend of improvement after regular practice of supine rest of 3 months though statistically not significant.Bangladesh Soc Physiol. 2017, December; 12(2): 65-71

show abstract

“…11,12 Regular practise of meditation reduces catecholamine, adrenal-cortical hormones and may help reducing blood pressure. 13,14 Thus meditation can be useful as primary intervention strategy to prevent development of hypertension and its complications.…”

Section: Introductionmentioning

confidence: 99%