Effectivity Antibacterial Zinc Oxide Eugenol With Zinc Oxide Propolis for Endodontic Treatment in Primary Teeth

Rahman, Erwid Fatchur; Christiono, Sandy

doi:10.30659/odj.6.2.113-117

Cited by 3 publications

(3 citation statements)

References 4 publications

(5 reference statements)

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“…12 Bacterial growth can be inhibited by flavonoids because it can form complexes with proteins through hydrogen bonding. 16 The function of flavonoid in inhibiting the growth of Enterococcus faecalis has a mechanism by inhibiting the function of the bacterial cytoplasmic membrane by forming complex compounds with extracellular proteins so it can damage the cytoplasmic membrane of bacterial cells followed by the release of intracellular compounds, loss of cations and macromolecules from cells, cause disruption of cell growth and bacterial cell death, this causes the growth of Enterococcus faecalis bacteria were inhibited. 17,18 The next metabolite compound of kelakai leaf that act against the Enterococcus faecalis bacteria is saponin.…”

Section: Resultsmentioning

confidence: 99%

Antibacterial Effect of Kelakai Leaf Extract (Stenochlaena Palustris (Burm) Bedd.) for Inhibiting Enterococcus Faecalis

Firdaus

Dewi

Fuady

et al. 2022

ODONTO : Dental Journal

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Background: Root canal treatment is a stage of treating pulp infection by removing the necrotic tissue and eliminating microorganisms. Inadequate sterilization cause persistent root canal bacteria, including Enterococcus faecalis. The irrigation solution that has become the gold standard in root canal treatment is Sodium hypochlorite but it has some weaknesses. Kelakai leaf extract can be an alternative root canal irrigation because it has minimal side effects and antibacterial compounds such as flavonoid, saponin, alkaloid, and tannin.Methods: This research was a true experimental laboratory with posttest only and control group design. The research using 5 treatment groups with 3 replications, so that total sample was 15 samples. Group 1-4 were kelakai leaf extract concentrations of 25%, 50%, 75%, 100% and group 5 was Sodium hypochlorite 2,5%. The parameter measured was the diameter of the inhibition zone (mm) formed on MHA.Results: One Way Anova and Post Hoc LSD test results showed a significant difference between each treatment group of kelakai leaf extract compared with Sodium hypochlorite 2,5%. Kelakai leaf extract 25%, 50%, 75%, 100% concentrations, and Sodium hypochlorite 2,5% had an average inhibition zone diameter which were 9.47 mm, 14.64 mm, 17.91 mm, 21.24 mm, and 23.27 mm.Conclusion: Kelakai leaf extract concentrations of 25%, 50%, 75%, and 100% had inhibitory activity against Enterococcus faecalis but had not been equivalent to Sodium hypochlorite 2,5%.

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Section: Resultsmentioning

confidence: 99%

Antibacterial Effect of Kelakai Leaf Extract (Stenochlaena Palustris (Burm) Bedd.) for Inhibiting Enterococcus Faecalis

Firdaus

Dewi

Fuady

et al. 2022

ODONTO : Dental Journal

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“…[ 15 ] reported the new ZOP paste (zincoxide with propolis ) achieved clinical success rate of 93.8% and radiographic success rate of 62.5% after 12 months, while ZOE achieved clinical success rate 87.5% and radiographic success rate 56.3% after 12 months. Another study by Rahman and Christiono[ 33 ] concluded that ZOP has lower antibacterial effectiveness on the Enterococcus faecalis than ZOE. Gupta et al .…”

Section: Discussionmentioning

confidence: 99%

Comparative evaluation of zinc oxide-eugenol and zinc oxide with Neem oil in root canal treatment of primary teeth: Split-mouth study with 12 months follow-up

Patel,

Fernandes,

Bafna

et al. 2022

AYU

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Background: Various root canal filling materials are used to preserve pulp tissue involved carious the primary tooth. A single material that fulfills all the requirements of an ideal root canal filling material for primary teeth is yet unavailable. Hence, this study was initiated to evaluate clinically and radiographically, the efficacy of two obturating materials – zinc oxide eugenol (ZOE) and zinc oxide mixed with Neem oil (ZON) for 12 months. Aims: To assess the success rate of a mixture of zinc oxide and neem oil in comparison to zinc oxide-eugenol paste, as an obturating material in primary molars. To compare the efficacy of ZON as an obturating material at the various time interval of 3, 6, 9, and 12 months postoperatively. Materials and methods: This split-mouth, double-blind study was performed on 24 children aged 5–7 years, who presented with bilaterally infected primary molars. Total 48 infected primary molars were divided into two groups for pulpectomy followed by obturation with ZOE and ZON, respectively. Randomization with the chit-pick method, for the control and experimental drug, was performed. A follow-up for 12 months was performed. The Chi-square test was used for inter-group comparison and the Z test was used for the analysis of data over a period of time. Results: Overall clinical findings in this study revealed 91.7% results in ZOE compared with 100% results in the ZON group. The radiographical findings revealed 91.7% results in ZOE compared with 100% success in the ZON group. Conclusion: ZON demonstrated excellent effectiveness as an obturating material in the 12-month follow-up period as compared to ZOE in primary teeth. The efficacy elicited in this study could be a basis to recommend ZON as herbal alternative obturation material.

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“…107 Since 1930s, ZnO has been most widely used as a root canal lling material. 108 It has been reported that nanosize materials play a signicant role in the regenerative endodontic eld and disinfection of the root canal space. It is known that ZnO is nearly insoluble in water due to high polarity; therefore, nanostructures of ZnO might be helpful to overcome this limitation.…”

Section: Endodonticmentioning

confidence: 99%

An overview of recent progress in dental applications of zinc oxide nanoparticles

et al. 2021

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Effectivity Antibacterial Zinc Oxide Eugenol With Zinc Oxide Propolis for Endodontic Treatment in Primary Teeth

Cited by 3 publications

References 4 publications

Antibacterial Effect of Kelakai Leaf Extract (Stenochlaena Palustris (Burm) Bedd.) for Inhibiting Enterococcus Faecalis

Antibacterial Effect of Kelakai Leaf Extract (Stenochlaena Palustris (Burm) Bedd.) for Inhibiting Enterococcus Faecalis

Comparative evaluation of zinc oxide-eugenol and zinc oxide with Neem oil in root canal treatment of primary teeth: Split-mouth study with 12 months follow-up

An overview of recent progress in dental applications of zinc oxide nanoparticles

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