Effectiveness of anesthetic solutions for pain control in lower third molar extraction surgeries: a systematic review of randomized clinical trials with network meta-analysis

Altmetric analysis of third molar surgery

“…The distribution between these two analyzes is unequal. It should be noted that high-grade journals such as The Lancet and Nature Medicine have a lot of citations but not that big AAS (Levine et al, 1978& Gear et al, 1996 Article without citation but with score in AAS; the article has not yet been cited in another article, but it is disseminated worldwide via social media (Rossi et al, 2020). In addition, articles with numerous citations could also be more widely disseminated through the use of social media, in particular Twitter and Facebook (Friedman, 2007), as a supplementary analysis to bibliometrics.…”

The potential of articaine as new generation of local anesthesia in dental clinics: A review

“…[46] A meta-analysis on the efficacy and safety of articaine in the extraction of mandibular third molars showed that the use of 4% articaine for the extraction of mandibular third molars was a safer option than other amide local anesthetics, required less dose, and had a shorter onset time. [47] Oertel et al suggested that articaine should be selected for local anesthesia in outpatient surgery of oral and maxillofacial surgery. [40] [48,49] In the past, using lidocaine for nerve block anesthesia was the main anesthesia method in oral implantology; however, the onset time of anesthesia was long, the failure rate of anesthesia was high, and it was difficult to control the extent of anesthesia.…”

“…[46] A meta-analysis on the efficacy and safety of articaine in the extraction of mandibular third molars showed that the use of 4% articaine for the extraction of mandibular third molars was a safer option than other amide local anesthetics, required less dose, and had a shorter onset time. [47] Oertel et al suggested that articaine should be selected for local anesthesia in outpatient surgery of oral and maxillofacial surgery. [40]…”

Ciencia de la eficacia anestésica de la articaína y de la lidocaína en exodoncias de terceros molares inferiores. Una revisión de literatura

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The efficacy of a local anesthetic in a surgical procedure such as lower third molar extraction is very important given the complexity of this procedure such as incision, flap, odontosection and ostectomy, curettage, lavage and suture.Local anesthetics are drugs that reversibly inhibit nerve conduction in the area where they are applied (Almeida et al, 2020), inhibiting the perception of pain, with the sequence being: increased skin temperature and vasodilation, loss of pain and thermal sensitivity, loss of perception, loss of sensation of touch and pressure and loss of motor skills (Arribas Blanco et al, 2001), the anesthetic effect varies between 2 to 4 hours approximately.Currently, several studies suggest that Articaine 4% should be used in extractions of lower third molars because it has better clinical properties compared to Lidocaine 2%, both associated with epinephrine 1: 100,000000 (Almeida et al, 2020) (Zhang et al, 2021) (Vademecun, 2020 (Larocca de Geus et al, 2020) (Rossi et al, 2021) (Baeza et al, 2020, , these are amide group anesthetics and both have been shown to be safe for any dental procedure that requires avoiding intense pain (endodontics, restorations, extractions, etc. ).

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“…Currently, several studies suggest that Articaine 4% should be used in extractions of lower third molars because it has better clinical properties compared to Lidocaine 2%, both associated with epinephrine 1: 100,000000 (Almeida et al, 2020) (Zhang et al, 2021) (Vademecun, 2020 (Larocca de Geus et al, 2020) (Rossi et al, 2021) (Baeza et al, 2020, , these are amide group anesthetics and both have been shown to be safe for any dental procedure that requires avoiding intense pain (endodontics, restorations, extractions, etc. ).…”