The potential of articaine as new generation of local anesthesia in dental clinics: A review

Luo, Wen; Zheng, Kaiyue; Kuang, Huifang; Li, Zhixin; Wang, JinRong; Mei, Jie

doi:10.1097/md.0000000000032089

Cited by 5 publications

(1 citation statement)

References 51 publications

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“…When articaine is injected into the mandible during dental procedures, it diffuses through the bone and provides adequate anesthesia to the teeth and surrounding tissues. (10) This is because articaine has a unique chemical structure that allows it to easily penetrate bone and reach the nerves that supply sensation to the teeth and mucosa. (11)The benzene ring on the right side represents the phenyl group, which gives the articaine its aromatic properties.…”

Section: Discussionmentioning

confidence: 99%

Is Articaine Associated with Higher Neurosensory Disturbance than Lidocaine in the Inferior Alveolar Nerve Block?

Tabrizi,

Mazidi,

Azadi

et al. 2023

Preprint

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Purpose Neurosensory disturbance (NSD) may occur following the inferior alveolar nerve blocks (IANBs).The study aims to investigate whether there is a difference in the prevalence of NSD) between patients who received lidocaine 2% and those who received articaine 4% during IANBs. Materials and Methods This is a double-blind, randomized clinical trial study. Patients who underwent the third molar extraction randomly were divided into two groups. In group 1, subjects IANB was performed using articaine 4%, and in group 2, lidocaine 2%.The occurrence of NSD was documented. Patients were visited within 48 hours and one week after the tooth removal. The type of anesthetic drug (articaine 4% versus Lidocaine 2%) is the study’s predictive factor. Results Two thousand four hundred subjects were studied in two groups (1200 subjects in each group). The mean age was 28.40 ± 6.76 years (minimum 18 and maximum 44 years). In group 1 (Lidocaine), five subjects (0.4%) had NSD after injection, and seven subjects in group 2 ( articaiene) (0.6%). Data analysis did not demonstrate any significant difference in the prevalence of NSD between the two groups. (p = 0.77) Conclusion Concerning the study's results, the prevalence of NSD is not higher in articaine than lidocaine in IANBs

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Section: Discussionmentioning

confidence: 99%