Effectiveness of a mouthrinse containing active ingredients in addition to chlorhexidine and triclosan compared with chlorhexidine and triclosan rinses on plaque, gingivitis, supragingival calculus and extrinsic staining

Kumar, Santhosh; Patel, Swati; Tadakamadla, Jyothi; Tibdewal, Harish; Duraiswamy, Prabu; Kulkarni, Sudhindra

doi:10.1111/j.1601-5037.2012.00560.x

Cited by 35 publications

(39 citation statements)

References 36 publications

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“…As we noted above, an important advantage of MTC over CHX is that patients in the 1% MTC group did not report side effects commonly associated with CHX, including ulcerations, allergic reactions, burning sensation, change in taste, supragingival calculus deposition, and tooth staining (29).…”

Section: Discussionmentioning

confidence: 96%

Clinical efficacy of a 1% <i>Matricaria chamomile </i>L. mouthwash and 0.12% chlorhexidine for gingivitis control in patients undergoing orthodontic treatment with fixed appliances

Góes

Dutra

Lisboa

et al. 2016

Journal of Oral Science

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Section: Discussionmentioning

confidence: 96%

Clinical efficacy of a 1% <i>Matricaria chamomile </i>L. mouthwash and 0.12% chlorhexidine for gingivitis control in patients undergoing orthodontic treatment with fixed appliances

Góes

Dutra

Lisboa

et al. 2016

Journal of Oral Science

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“…Dental plaque is a sticky and soft biofilm that is formed on the tooth surface (1,2). It begins to form on tooth surfaces within only a few minutes after brushing the teeth.…”

Section: Introductionmentioning

confidence: 99%

The clinical evaluation of Vi-one chlorhexidine mouthwash on plaque-induced gingivitis: A double-blind randomized clinical trial

Amoian¹,

Omidbakhsh²,

Khafri³

2017

Electron Physician

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BackgroundChlorhexidine (CHX) is the most effective antiseptic mouthwash to date. Essential oil such as thymol, have inhibitory and biocidal effects a range of bacteria.ObjectiveTo determine the effect of mouthwash containing CHX and thymol on plaque induced gingivitis.MethodsThis double-blind randomized clinical trial study was performed on 60 patients with plaque induced gingivitis who were randomly divided into two groups: Group I (CHX/thymol mouthwash-Vi-one) and Group II (CHX mouthwash-Behsa). Patients in each group underwent scaling and root planning and polishing, then were educated about BASS-Method brushing, and were recommended Oral-B toothbrushes and Pooneh toothpaste. The two groups were asked to rinse their mouths for 60 seconds twice a day, once in the morning and once at night, after brushing their teeth. Plaque index, gingival index, bleeding index and stain index were evaluated at baseline and 14 days later in Ramfjord teeth. Data analysis was conducted using SPSS version 21. Independent-samples t-test and paired-samples t-test were used for data analysis.ResultsThe results showed that plaque index and gingival index significantly reduced in two groups (p<0.001). However, group I was significantly more efficient than group II (p<0.001, p=0.021 respectively). Similar results were observed in terms of bleeding index with the difference that the two groups did not differ significantly from each other (p=0.879). Both groups significantly increased the stain index. No remarkable difference was also observed between the two groups (p=0.754).ConclusionBased on the results of this study, we can conclude that the CHX/thymol mouthwash can be offered to patients with dental plaque-induced gingivitis, because it appears to be more effective in controlling dental plaque and gingivitis.Trial registrationThe trial was registered at the Iranian Registry of Clinical Trials (http://www.irct.ir) with the Irct ID: IRCT201602231760N45.FundingThis study was part of a thesis and research project (Grant No: 9440921) supported and funded by Babol University of Medical Sciences. The authors received no financial support from Behsa pharmaceutical company (Behsa mouthwash manufacturer) or Rojin cosmetic laboratory (Vi-one mouthwash manufacturer) for this study.

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“…De todos los enjuagatorios estudiados, éste ejerce un efecto más prolongado sobre el aumento de pH lo cual favorecería el proceso de remineralización del esmalte. Sin embargo, numerosos estudios hacen referencia de la tendencia de clorhexidina a contribuir con la formación de cálculos supragingivales (Eley;Kumar et al, 2013;Calderini et al, 2013). La leve disminución de proteínas In vivo (p>0,05) entre 5 y 10 min, sumado a la presencia de tenues bandas de proteínas de peso molecular inferior a 66 kDa observadas por SDS -PAGE, llevan a postular que clorhexidina, debido a su carácter catiónico, tiende a formar complejos insolubles con proteínas aniónicas como albúmina y mucinas, las que se encuentran dentro del rango de peso molecular mencionado (Tsuchiya et al; Musteata & Pawliszyn).…”

Section: Discusionunclassified

Acción Inmediata de los Enjuagues Orales en la Saliva

Vargas

Koss

López

2017

Int. J. Odontostomat.

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VARGAS, C. F.; KOSS, M. A. & LÓPEZ, M. E.Acción inmediata de los enjuagues orales en la saliva. Int. J. Odontostomat., 11(3):339-346, 2017. RESUMEN:Numerosos estudios confirman la efectividad de los enjuagatorios orales sobre la viabilidad de los microorganismos que producen gingivitis y halitosis, pero poco se conoce sobre la influencia de los mismos en el medio ambiente oral. El objetivo del siguiente trabajo fue analizar In vivo e In vitro el efecto de enjuagatorios orales sobre la saliva total no estimulada. Se trabajó con saliva de individuos sanos. Para el estudio in vivo se recogieron las muestras antes y después del enjuague oral a diferentes tiempos (1, 5, 10, 15, 30, 45 y 60 minutos). Para el ensayo in vitro, se incubó la saliva con igual volumen de la solución enjuagatoria a 37 ºC con agitación a diferentes tiempos (1, 5, 10 y 15 minutos). Se determinó pH inmediatamente recogidas las muestras. Posteriormente fueron centrifugadas y determinados flujo salival y proteínas totales. La separación de proteínas por electroforesis en SDS-PAGE se realizó solo en el ensayo in vivo. Los resultados mostraron que los enjuagatorios fluorurados poco alteran la fisiología oral a través de flujo salival, pH y proteínas totales. La combinación fluoruro de sodio/xilitol produjo mayor estimulación del flujo salival. La mezcla de aceites esenciales provocó un incremento del flujo salival y de pH, redujo el contenido de proteínas totales, evidenciando por SDS-PAGE que las comprometidas fueron particularmente las de mediano y bajo peso molecular. Clorhexidina debido a su elevada sustantividad, incrementó significativamente flujo salival y pH in vivo. In vitro, fuera del medioambiente oral, los enjuagatorios estudiados ejercieron un efecto similar sobre proteínas totales. Los enjuagatorios de uso frecuente alteraron parámetros salivales, por lo que podría estudiarse la acción que ejercen sobre otros componentes de la saliva con actividad biológica importante en cavidad oral.

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Effectiveness of a mouthrinse containing active ingredients in addition to chlorhexidine and triclosan compared with chlorhexidine and triclosan rinses on plaque, gingivitis, supragingival calculus and extrinsic staining

Cited by 35 publications

References 36 publications

Clinical efficacy of a 1% <i>Matricaria chamomile </i>L. mouthwash and 0.12% chlorhexidine for gingivitis control in patients undergoing orthodontic treatment with fixed appliances

Clinical efficacy of a 1% <i>Matricaria chamomile </i>L. mouthwash and 0.12% chlorhexidine for gingivitis control in patients undergoing orthodontic treatment with fixed appliances

The clinical evaluation of Vi-one chlorhexidine mouthwash on plaque-induced gingivitis: A double-blind randomized clinical trial

Acción Inmediata de los Enjuagues Orales en la Saliva

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