Effectiveness comparisons of Chinese patent medicine on treating premature ejaculation

Sun, Shujuan; Mo, Xuwei; Li, Yufeng; Gong, Ziqi; Wang, Jisheng; Yu, Xiaohua; Han, Liang; Zhou, Hong

doi:10.1097/md.0000000000017729

Cited by 4 publications

(2 citation statements)

References 20 publications

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“…CPMs are widely used as a substitute and adjuvant to western medicines ( 25 ). They are one of the most important parts of TCM used in clinical practice as derivatives of Chinese herbal medicine ( 26 ). Modern pharmacological research has led to the use of greater numbers of Chinese medicine extracts in modern pharmaceutical preparations, including oral CPM (OCPM) and Chinese medicine injection ( 27 ).…”

Section: Introductionmentioning

confidence: 99%

Treatment of endometriosis with dienogest in combination with traditional Chinese medicine: A systematic review and meta-analysis

Liu²,

Jia³

et al. 2022

Front. Surg.

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BackgroundEndometriosis is now considered to be a systemic disease rather than a disease that primarily affects the pelvis. Dienogest (DNG) has unique advantages in the treatment of endometriosis, but it also has side effects. Alternatively, Traditional Chinese Medicine (TCM) has been used for over 2000 years in the treatment and prevention of disease and growing numbers of Chinese scholars are experimenting with the combined use of Dienogest and TCM for endometriosis treatment.ObjectivesThis review evaluated the efficacy and safety of TCM in combination with Dienogest in the treatment of endometriosis through meta-analysis.MethodsMEDLINE, Embase, the Cochrane Library, PubMed, Web of Science, China National Knowledge Infrastructure, Journal Integration Platform, and Wanfang were used in literature searches, with a deadline of May 31, 2022. Literature quality was assessed using the Cochrane Collaboration “risk of bias” (ROB2) tool, and the “meta” package of R software v.4.1 was used for meta-analysis. Dichotomous variables and continuous variables were assessed using the relative risk (RR) and 95% confidence intervals (95% CI); standard mean differences (MD) and 95% CI, respectively.ResultsTwelve human randomized controlled trials (RCTs) and one retrospective study, all 13 written in the Chinese language, were included in the meta-analysis (720 experiments and 719 controls). The result indicated that TCM plus Dienogest was superior to Dienogest/TCM alone in increasing the cure rates (RR = 1.3780; 95% CI, 1.1058, 1.7172; P = 0.0043), remarkable effect rate (RR = 1.3389; 95% CI, 1.1829, 1.5154; P < 0.0001), invalid rate (RR = 0.2299; 95% CI, 0.1591, 0.3322; P < 0.0001), and rate of adverse effects (RR = 0.6177; 95% CI, 0.4288, 0.8899; P = 0.0097). The same conclusion was drawn from the subgroup analysis.ConclusionResults suggest that TCM combined with Dienogest is superior to Dienogest or TCM alone and can be used as a complementary treatment for endometriosis. TCMs have potential to improve clinical efficacy and reduce the side effects of Dienogest. This study was financially supported by Annual Science and Technology Steering Plan Project of Zhuzhou. PROSPERO has registered our meta-analysis as CRD42022339518 (https://www.crd.york.ac.uk/prospero/record_email.php).

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Section: Introductionmentioning

confidence: 99%

Treatment of endometriosis with dienogest in combination with traditional Chinese medicine: A systematic review and meta-analysis

Liu²,

Jia³

et al. 2022

Front. Surg.

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“…Patients around the world also benefit from TCM extract, such as artemisinin, an antimalarial drug [ 1 ]. As an important part of CHM, Chinese patent medicine (CPM) is a production of a fixed formula of TCM processed in accordance with the prescribed prescriptions and standards and approved by China National Medical Products Administration (NMPA) [ 2 ]. Eczema is a common chronic, inflammatory skin disease, which presents as redness, scaling, swelling, and skin thickening.…”

Section: Introductionmentioning

confidence: 99%

Reporting Quality of Randomized Controlled Trials for the Treatment of Eczema with Chinese Patent Medicine Based on the CONSORT-CHM Formulas 2017

Zhou

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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Objective. Chinese patent medicine (CPM) has been widely used to treat eczema in mainland China for decades. This study aims to investigate circulating CPM for eczema in mainland China and to evaluate the reporting quality of randomized controlled trials (RCTs) of them by using the CONSORT-CHM formulas 2017 (Consolidated Standards of Reporting Trials for Chinese herbal medicine formulas 2017). Methods. Circulating CPM with the indication for eczema was selected by searching three drug databases and confirmed by contacting the manufacturers. RCTs for the treatment of eczema with CPM were selected in four Chinese literature databases and four English literature databases from their inception to August 31, 2019. The reporting quality of included RCTs was assessed based on the CONSORT-CHM formulas 2017. A univariate analysis was conducted to identify the factors associated with the reporting quality. Results. A total of 70 circulating CPMs had the indication for eczema. Among them, 21 CPMs with 144 RCTs reached the eligible criteria. The mean overall quality score (OQS) of 144 RCTs was 19.85 ± 2.73, which was much less than the maximum score of 38. Of the 38 items, 12 items were reported in over 70% of the trials, 6 items were reported in 50%–70% of the trials, and 16 items were reported in less than 50% of the trials. Publication after 2015 (P<0.001) and the first author from a university hospital (P=0.010) were associated with the better reporting quality. Conclusion. There are a lot of circulating CPMs with the indication for eczema in mainland China, but both the quantity and the reporting quality of RCTs regarding those CPMs are suboptimal. It is necessary that authors and journal editors learn and adhere to the CONSORT-CHM formulas 2017 to enhance the reporting quality of RCTs for the treatment of eczema with CPM.

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Chinese patent medicine for osteoporosis: a systematic review and meta-analysis

et al. 2022

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Effectiveness comparisons of Chinese patent medicine on treating premature ejaculation

Cited by 4 publications

References 20 publications

Treatment of endometriosis with dienogest in combination with traditional Chinese medicine: A systematic review and meta-analysis

Treatment of endometriosis with dienogest in combination with traditional Chinese medicine: A systematic review and meta-analysis

Reporting Quality of Randomized Controlled Trials for the Treatment of Eczema with Chinese Patent Medicine Based on the CONSORT-CHM Formulas 2017

Chinese patent medicine for osteoporosis: a systematic review and meta-analysis

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