Effect of the Association between Citric Acid and EDTA on Root Surface Etching

Abstract

Root conditioning with citric acid alone and before EDTA had the best results for smear layer removal and clot stabilization. EDTA inhibited clot stabilization on root surface and must have a residual activity once it has diminished clot adhesion to root even after citric acid conditioning. Thus, EDTA can be used to neutralize citric acid effects on periodontal cells without affecting clot stabilization. Clinical signifcance: To demonstrate that citric acid use on root surfaces previously affected by periodontal disease may favor clot stabilization and may have a benefcial effect on surgical outcomes. Also, EDTA can be used to neutralize citric acid effects on periodontal cells.

Blood clot stabilization on root dentin conditioned by the combination of tetracycline and EDTA

“…For these reasons, the use of demineralizing agents has been studied as an adjunct to periodontal therapy, since these agents present a great potential not only for removing smear layer 4 , but also to expose the underlying radicular collagen fibrils and to restore the biocompatibility of the roots 5 . These properties are necessary to increase fibrin network linkage to root collagen fibers, resulting in a better periodontal regenerative procedure 4,6 .…”