Effect of seasonal variation on the anti-inflammatory activity of Sargassum wightii growing on the N. Arabian Sea coast of Pakistan

Towards a better understanding of medicinal uses of the brown seaweed Sargassum in Traditional Chinese Medicine: A phytochemical and pharmacological review

“…No acute toxicity in mice was observed after oral administration of 5 g/kg of body weight of dichloromethane, ethanol and boiling water extracts of S. fulvellum and S. thunbergii . No acute toxicity in mice was observed for intraperitoneal injection of 500 mg/kg of body weight of hexane, sequential methanol and butanol extracts of S. wightii (Dar et al, 2007).…”

Inhibitory Effect of Sargauum fulvellum Ethanolic Extract on LPS-Induced Inflammatory Reaction in RAW 264.7 Mouse Macrophages

“…In addition, the bioactive compounds like alginic acid, laminarin, iodine, and fucoidin from brown seaweed are well known to inhibit or prevent a variety of inflammatory diseases by suppressing the secretion of inflammatory mediators in activated macrophages (Li et al, 2011). Sargassum is tropical and sub-tropical brown algae comprising 150 species, common to all oceans except Antarctica (Dar et al, 2007). Sargassum have been studied extensively, and polysaccharides extracted from different Sargassum algae such as S. dentifolium (Amira et al, 2013), S. wightii (Josephine et al, 2008), S. thunbergii and others (Kang et al, 2008) were reviewed and showed the diverse bioactivities such as anti-oxidant, antiinflammatory, anti-genotoxic, and anti-cancer.…”

Polysaccharides from Sargassum tenerrimum: Structural features, chemical modification and anti-viral activity

“…The marine brown alga Sargassum tenerrimum possesses various biological activities (Dar et al, 2007;Kang et al, 2008;Ye et al, 2008). Recently, there is a report on the anti-viral activity of a crude extract from S. tenerrimum (Zhu et al, 2006).…”