Effect of Pupil Size on Biometry Measurements Using the IOLMaster

Adler, G; Shahar, Jonathan; Kesner, Rivka; Rosenfeld, Eldar; Fischer, Naomi; Loewenstein, Anat; Kurtz, Shimon

doi:10.1016/j.ajo.2015.01.025

Cited by 19 publications

(32 citation statements)

References 29 publications

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“…Thus, no significant change in AL is produced in response to pupil dilation using both the IOLMaster 500 © and LENSTAR © [6][7][8][9][10]. The slight, though significant, increase in CCT observed in our study is consistent with the findings of other authors, who noted significant increases in CCT after pupil dilation with tropicamide eye drops [14,15].…”

Section: Discussionsupporting

confidence: 90%

“…In three studies examining the effect of pupil dilation in IOLMaster 500 © measurements [6][7][8], no effects were observed on AL and only one study reported a significant difference in pre-and post dilation MK data [6]. In addition, in the only one study in which the ACD was measured, this variable was found to increase after pupil dilation.…”

Section: Discussionmentioning

confidence: 96%

“…In the only study in which a change in MK measured by optical biometry was detected after pupil dilation, the authors attributed this to chance [6]. Effectively, other optical biometry studies have revealed no change in corneal curvature after pupil dilation [7][8][9][10] and Effect of pupil dilation on measurements and IOL power calculation with IOLMaster700 5 …”

Section: Discussionmentioning

confidence: 99%

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Effect of pharmacological pupil dilation on measurements and iol power calculation made using the new swept-source optical coherence tomography-based optical biometer

Arriola‐Villalobos

Almendral-Gómez

Garzón³

et al. 2016

Journal Français d'Ophtalmologie

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Please cite this article in press as: Arriola-Villalobos P, et al. Effect of pharmacological pupil dilation on measurements and iol power calculation made using the new swept-source optical coherence tomography-based optical biometer. J Fr Ophtalmol (2016) Please cite this article in press as: Arriola-Villalobos P, et al. Effect of pharmacological pupil dilation on measurements and iol power calculation made using the new swept-source optical coherence tomography-based optical biometer. J Fr Ophtalmol (2016) Procedures. -Eighty-one eyes of 81 patients evaluated for cataract surgery were prospectively examined using the IOLMaster 700 © before and after pupil dilation with tropicamide 1%. The measurements made were: axial length (AL), central corneal thickness (CCT), aqueous chamber depth (ACD), lens thickness (LT), mean keratometry (MK), white-to-white distance (WTW) and pupil diameter (PD). Holladay II and SRK/T formulas were used to calculate IOL power. Agreement between measurement modes (with and without dilation) was assessed through intraclass correlation coefficients (ICC) and Bland-Altman plots. Results. -Mean patient age was 75.17 ± 7.54 years (range: 57-92). Of the variables determined, CCT, ACD, LT and WTW varied significantly according to pupil dilation. Excellent intraobserver correlation was observed between measurements made before and after pupil dilation. Mean IOL power calculation using the Holladay 2 and SRK/T formulas were unmodified by pupil dilation.Conclusions. -The use of pupil dilation produces statistical yet not clinically significant differences in some IOLMaster 700 © measurements. However, it does not affect mean IOL power calculation. © 2016 Elsevier Masson SAS. All rights reserved. MOTS CLÉSCohérence optique swept-source ; Dilatation pupillaire ; Biométrie ; Cataracte ; IOLMaster 700 © Résumé Propos. -Déterminer si la dilatation pupillaire modifie les mesures biométriques et le calcul de la puissance de l'implant intraoculaire obtenus avec un nouveau biomètre optique basé sur la tomographie par cohérence optique swept-source (IOLMaster 700 © ; Carl Zeiss Meditec, Jena, Allemagne) Méthodes. -Nous avons évalué prospectivement 81 yeux de 81 patients prévus pour la chirurgie de la cataracte au moyen du biomètre IOLMaster 700 © , avant et après dilatation pupillaire avec tropicamide 1 %. Les mesures réalisées ont été : longueur axiale (AL), épaisseur cornéenne centrale (CCT), profondeur de la chambre antérieure (épaisseur cornéenne exclue) (ACD), épaisseur cristallinienne (LT), kératométrie moyenne (MK), distance blanc à blanc (WTW) et diamètre pupillaire (PD). Les formules Holladay II et SRK/T ont été employées pour calculer la puissance de l'implant intraoculaire. Nous avons évalué la concordance entre les deux méth-odes de mesure (sous dilatation pupillaire et sans) au moyen des coefficients de corrélation intraclasse (ICC) et des graphiques de Bland-Altman. Résultats. -La moyenne d'âge des patients était de 75,17 ± 7,54 ans (intervalle : 57-92). Parmi les variables mesurées, la CCT,...

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Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of pharmacological pupil dilation on measurements and iol power calculation made using the new swept-source optical coherence tomography-based optical biometer

Arriola‐Villalobos

Almendral-Gómez

Garzón³

et al. 2016

Journal Français d'Ophtalmologie

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“…12) Adler et al also indicated similar results. 17) These results were reasonable since SRK/T does not include ACD as a biometric parameter, which is significantly affected by pupil dilation,…”

Section: Resultsmentioning

confidence: 67%

Influence of pupil dilation on the Barrett Universal II (new generation), Haigis (4th generation), and SRK/T (3rd generation) intraocular lens calculation formulas: a retrospective study

Teshigawara

Meguro

Mizuki

2020

Preprint

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Background: We investigated the effect of pupil dilation on predicted postoperative refraction (PPR) and recommended intraocular lens (IOL) power calculated using three different generations of IOL power calculation formulas: Barrett Universal II (Barrett) (new generation), Haigis (4th generation), and SRK/T (3rd generation). Methods: This retrospective study included 150 eyes. All variables were measured and calculated using a ZEISS IOL Master 700. The following variables were measured before and after dilation: anterior chamber depth (ACD), lens thickness (LT), white-to-white (WTW). PPR and recommended IOL power were calculated by Barrett, Haigis, and SRK/T IOL calculation formulas. The change in each variable before and after dilation, and correlations between all changes were analyzed using the Wilcoxon signed-rank test and the Spearman’s rank-order correlation test, respectively. The influence of pupil dilation on recommended IOL power calculated by each formula was also analyzed. Results: The mean absolute change (MAC) in PPR before and after dilation was highest in Barrett, followed by Haigis and SRK/T. Significant differences were found among each MACs (P < 0.0001). Significant changes were observed before and after dilation in ACD and LT (P < 0.0001) but not in WTW. In Barrett and Haigis, there was a significant positive correlation between change in PPR and change in ACD (P < 0.0001) and a negative correlation between change in PPR and change in LT (P < 0.0001). Correlations were strongest in Barret followed by Haigis, especially in LT. Change in PPR in Barrett also demonstrated a significant positive correlation with change in WTW (P = 0.022). The recommended IOL power using Barrett and Haigis changed before and after dilation in 23.3% and 19.3% cases; SRK/T showed no change. Conclusions: In PPR and recommended IOL power, pupil dilation influenced Barrett most strongly, followed by Haigis and SRK/T. Given the stronger correlation between the change in PPR in Barrett and the change in ACD, LT, and WTW, the change of ACD, LT, and WTW is more important to the influence of dilation on Barrett. The influence of dilation on each formula and variable, including ACD, LT, and WTW, is key to improving IOL calculation.

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“…They concluded that cycloplegia affected ACD and WTW but not AL or corneal curvature measurements. Adler et al showed there is no clinically significant effect of pupil dilation on the IOL Master measurements of AL, corneal power, and corresponding theoretical IOL calculated using the Sanders‐Retzlaff‐Kraff/Theoretical formula. Besides Lenstar and IOL Master 500, accurate and repeatable outcomes have been reported with IOL Master 700 as well .…”

Section: Discussionmentioning

confidence: 99%

The effect of cycloplegia on biometric measurements using swept‐source optical coherence tomography‐based biometry

Özçalışkan

Yenerel

2019

Clinical and Experimental Optometry

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Background: To evaluate the effect of pupil dilation obtained with cyclopentolate on biometric measurements using swept-source optical coherence tomography biometry. Methods: This study involved 63 eyes of 63 healthy volunteers. After ophthalmic examination, biometry measurements of the participants were obtained with IOL Master 700 (Carl Zeiss Meditec AG, Jena, Germany). After pre-dilation measurements were taken, subjects were given one drop of cyclopentolate hydrochloride ophthalmic solution three times at 10-minute intervals. When cycloplegia had been achieved, a dilated fundus examination was conducted and post-dilation measurements were taken with IOL Master 700. The biometric parameters were recorded and SPSS Software 22.0 was used for statistical analysis. Results: There was a significant increase in anterior chamber depth, anterior aqueous depth and central corneal thickness values after pupil dilation (p < 0.05). A significant decrease was observed in lens thickness values after cycloplegia (p < 0.05). There were no statistically significant differences between pre-dilation and post-dilation axial length, keratometry (K1, K2) and white-to-white values (p > 0.05). Conclusion: This study demonstrated there is no significant difference in axial length and keratometry measurements using swept-source optical coherence tomography biometry before and after cycloplegia.

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Effect of Pupil Size on Biometry Measurements Using the IOLMaster

Cited by 19 publications

References 29 publications

Effect of pharmacological pupil dilation on measurements and iol power calculation made using the new swept-source optical coherence tomography-based optical biometer

Effect of pharmacological pupil dilation on measurements and iol power calculation made using the new swept-source optical coherence tomography-based optical biometer

Influence of pupil dilation on the Barrett Universal II (new generation), Haigis (4th generation), and SRK/T (3rd generation) intraocular lens calculation formulas: a retrospective study

The effect of cycloplegia on biometric measurements using swept‐source optical coherence tomography‐based biometry

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