Effect of polysaccharide nanocrystals on structure, properties, and drug release kinetics of alginate-based microspheres

Supramolecular Nanofibrillar Polymer Hydrogels

“…An example of nanofibrillar gels in drug delivery is a pH-sensitive microspherebased controlled release system [227]. It utilizes CNCs, chitin nanowhiskers, and starch nanocrystals embedded within alginate microspheres, and illustrates the sustained release of the drug theophylline [228].…”

Crystalline starch based nanoparticles

“…A "green" method of ionic crosslinking through Ca 2+ , forming semiinterpenetrating polymeric networks (semi-IPN), was used to develop starch nanocrystal reinforced pH-sensitive alginate microsphere controlled release system for drug delivery [65]. Rod-like cellulose and chitin nanocrystals were also investigated in the study.…”

Effect of ultrasonic treatments on nanoparticle preparation of acid-hydrolyzed waxy maize starch

“…For example, in drug delivery systems, polysaccharide nanocrystals may exhibit prominent sustained release profiles, with assured safety (Lin, Huang, Chang, Feng, & Yu, 2011). Nanomaterials prepared from chitin and chitosan have proved effective for nanoencapsulation or for stabilizating nanoemulsions against coalescence (Tzoumaki, Moschakis, Kiosseoglou, & Biliaderis, 2011).…”