Supramolecular Nanofibrillar Polymer Hydrogels

Multi-component hybrid hydrogels – understanding the extent of orthogonal assembly and its impact on controlled release

“…80 nm. As expected, 20 agarose also formed a nanofibrillar gel, but with thinner fibres of ca. 10 nm (Fig.…”

“…This saccharide biopolymer has good biocompatibility forming a robust, stable hydrogel through a nanofibrillar mechanism. 20 …”

Supramolecular Polymer Networks: Preparation, Properties, and Potential

“…The development of donoracceptor π-π stacking interactions as transient cross-links in self-healable supramolecular polymer networks is discussed by Greenland and Hayes [304]. Chau, Sriskandha, Thérien-Aubin, and Kumacheva highlight recent progress in the field of nanofibrillar supramolecular gels, discussing both synthetic and natural materials [305], whereas Li and Liu add a particular view on the potential of cellulose and cellulose derivatives for the formation of chemical and physical gels and microgels, with a specific view to supramolecular interactions within them [306]. Finally, Pape and Dankers provide a review on supramolecular hydrogels of several of the preceding kinds for use in the field of regenerative medicine [307].…”

Structured Macroporous Hydrogels: Progress, Challenges, and Opportunities

“…[21,22] Macroporous nanofibrous networks are of particular interest in this regard given their capacity to mimic the fibrous nature of native extracellular matrix. [32] Structured macroporous hydrogels are a class of hydrogels with porosities and/or feature sizes in the micron range that can effectively combine the desirable properties of conventional hydrogels with the transport properties of conventional porous media. The wide range of preparation techniques, highlighted below, allows for precise control over both pore size, pore orientation, and gel morphology, leading to highly functional materials for targeted applications including filtration, directing cell growth, and templating other materials.…”