Effect of pharmaceutical care programme on blood pressure and quality of life in a nigerian pharmacy

Aguwa, C. N.; Ukwe, Chinwe Victoria; Ekwunife, Obinna Ikechukwu

doi:10.1007/s11096-007-9151-x

Cited by 39 publications

(52 citation statements)

References 10 publications

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“…The remaining 7 studies were not included because the data were not extractable 56,58,60 and a comparison contemporary control group was not used. [18][19][20]57 Effects on SBP. Sensitive outcomes were reported in 11 of 13 studies evaluating SBP.…”

Section: Control Groupmentioning

confidence: 99%

“…12 One systematic review, which included studies from 1978 to 2006, assessed pharmacist interventions in hypertensive patients in order to enhance patients' adherence to medication and reduce systolic BP (SBP) and diastolic BP (DBP). 13 Since then, several important RCTs [14][15][16][17] and non-RCTs [18][19][20] have been conducted to assess the effect of pharmacist interventions on medication adherence and BP control in hypertensive patients.…”

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confidence: 99%

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Pharmacist interventions to enhance blood pressure control and adherence to antihypertensive therapy: Review and meta-analysis

Morgado

Morgado²,

Mendes

et al. 2011

American Journal of Health-System Pharmacy

140

107

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Purpose. Pharmacist interventions to enhance blood pressure (BP) control and adherence to antihypertensive therapy in adults with essential hypertension were reviewed. Methods. A literature search was conducted to identify relevant articles describing pharmacist interventions intended to improve adherence to antihypertensive medications. Studies were included if they described a pharmacist intervention to improve medication adherence and analyzed adherence to therapy and BP control as outcomes. A fixed-effects model was used to combine data from randomized controlled trials. Results. A total of 15 studies were identified, testing 16 different interventions and containing data on 3280 enrolled patients. Although 87.5% of the interventions resulted in significant improvements in treatment outcomes, only 43.8% of the interventions were associated with significant increases in medication adherence. All interventions that increased antihypertensive medication adherence also significantly reduced BP. Almost all the interventions that were effective in increasing adherence to medication were complex, including combinations of different strategies. Metaanalysis of 2619 patients in 8 studies found that pharmacist interventions significantly reduced systolic blood pressure (SBP) (p < 0.001) and diastolic blood pressure (DBP) (p = 0.002) and that the meta-analytic differences in SBP and DBP changes from baseline to endpoint in intervention and control groups were -4.9 ± 0.9 mm Hg (p < 0.001) and -2.6 ± 0.9 mm Hg (p < 0.001), respectively. Conclusion. A literature review and metaanalysis showed that pharmacist interventions can significantly improve medication adherence, SBP, DBP, and BP control in patients with essential hypertension. Interventions were complex and multifaceted and included medication management in all analyzed studies.

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Section: Control Groupmentioning

confidence: 99%

mentioning

confidence: 99%

Pharmacist interventions to enhance blood pressure control and adherence to antihypertensive therapy: Review and meta-analysis

Morgado

Morgado²,

Mendes

et al. 2011

American Journal of Health-System Pharmacy

140

107

View full text Add to dashboard Cite

show abstract

“…It has been advocated to enable the pharmacists to describe their emerging role of patient-focused healthcare provision. It is defi ned as the responsible provision of drug-related care for the purpose of achieving defi nite outcomes that improve and/or maintain a patient's quality of life [2]. It is both patient-centered and outcome-oriented pharmacy practice that requires the Pharmacist to work together with the patient and other Healthcare providers to promote health, prevent disease, assess, monitor, initiate, and modify medication use to assure the safety and eff ectiveness of drug therapy regimens [3].…”

mentioning

confidence: 99%

Barriers to implementation of pharmaceutical care by pharmacists in Nsukka and Enugu metropolis of Enugu State

Okonta¹,

Okonta²,

Ofoegbu³

2012

J Basic Clin Pharma

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“…The value of 30 mmHg for the dpΔ was used from literature (Borges, 2008;Lyra-Jr, Marcellini, Pelá, 2008). A clinically satisfactory reduction in systolic blood pressure between 5-10 mm Hg were considered (Aguwa, Ukwe, Ekwunife, 2008;Lyra-Jr, Marcellini, Pelá, 2008). Thus, for an Ɛ value between 5-10 mmHg the sample number between 33 and 138 was calculated.…”

Section: Statisticmentioning

confidence: 99%

“…It is a model of professional practice in which the pharmacist uses clinical and humanistic skills to promote patient care through pharmacotherapeutic follow up (Ivama et al, 2002). Some studies have shown that PC is effective not only in controlling blood pressure, but also in reducing health complications caused by SAH (Machado et al, 2007;Aguwa, Ukwe, Ekwunife, 2008;Lyra-Jr, Marcellini, Pelá, 2008). However there is a need to assess the financial impact of PC together with clinical results achieved so this practice is encouraged in the PHS.…”

Section: Introductionmentioning

confidence: 99%

Cost-consequence analysis of Pharmaceutical Care program for systemic arterial hypertension in the public health system in Brazil

Cazarim

Nunes

Pereira

2018

Braz. J. Pharm. Sci.

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In Brazil, 80% of hypertensive patients have no blood pressure controlled, this fact has caused severe financial consequences for the public health system (PHS) and the Pharmaceutical Care (PC) has emerged as an effective alternative. The aim of this study was to analyze the costs and outcomes of systemic arterial hypertension (SAH) for conventional assistance compared to assistance with PC in the PHS. This is a pharmacoeconomic study with cost-consequence analysis nested to clinical trial. Hypertensives patients were followed-up from 2006 to 2012. During 2009 they were assisted by the PC program in Ribeirão Preto-SP, Brazil. Clinical indicators, systolic and diastolic blood pressure (SBP and DBP), triglycerides, total cholesterol (TC) and its fractions and healthcare indicators, consumption of antihypertensive medication and consultations were analyzed. Costs were listed as direct medical and direct non-medical. The average cost of conventional care for 104 patients followed-up was US$ 198.97, in the PC period and after discharge was US$ 407.91 and US$ 214.96 patient/year. After discharge of patients from PC there was reduction of SBP, DBP, TC and cardiovascular risk, 9.4 mmHg, 4.6 mmHg, 12.0 mg/dL, and 23% [p<0.005], respectively. The PC program optimized clinical and healthcare indicators and impacted in the SAH costs for the PHS.

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Effect of pharmaceutical care programme on blood pressure and quality of life in a nigerian pharmacy

Abstract: Pharmaceutical care programme could produce a beneficial effect on hypertensive patients.

Cited by 39 publications

References 10 publications

Pharmacist interventions to enhance blood pressure control and adherence to antihypertensive therapy: Review and meta-analysis

Pharmacist interventions to enhance blood pressure control and adherence to antihypertensive therapy: Review and meta-analysis

Barriers to implementation of pharmaceutical care by pharmacists in Nsukka and Enugu metropolis of Enugu State

Cost-consequence analysis of Pharmaceutical Care program for systemic arterial hypertension in the public health system in Brazil

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