Effect of percutaneous transluminal angioplasty on tissue oxygenation in ischemic diabetic feet

Kim, Hong Ryul; Han, Seung Kyu; Rha, Seung Woon; Kim, Hyun Surk; Kim, Woo Kyung

doi:10.1111/j.1524-475x.2010.00641.x

Cited by 26 publications

(18 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…After revascularization, TcPO 2 progressively improved in the successfully revascularized group, with a TcPO 2 >30 mm Hg in 38.5% of patients 1 week after PTA and reaching its peak value in the 4 th week by increasing to 75%. These results have been confirmed by others [16,17]. Pardo et al [16] performed a prospective study with 151 patients, 64 of which underwent revascularization via PTA, and then evaluated TcPO 2 pre-and postoperative and compared with ankleÀbrachial index (ABI).…”

Section: Transcutaneous Oxygen Monitoringsupporting

confidence: 70%

See 1 more Smart Citation

Contemporary assessment of foot perfusion in patients with critical limb ischemia

Benitez

Sumpio

Chin

et al. 2014

Seminars in Vascular Surgery

View full text Add to dashboard Cite

Section: Transcutaneous Oxygen Monitoringsupporting

confidence: 70%

“…Additionally, TcPO 2 could be measured in all patients, and the ABI could not be measured in 25.4% pretreatment and in 17.91% post treatment. Kim et al [17] reported on 29 diabetic patients with Fig. 1 -Angiosomes of the foot.…”

Section: Transcutaneous Oxygen Monitoringmentioning

confidence: 98%

Contemporary assessment of foot perfusion in patients with critical limb ischemia

Benitez

Sumpio

Chin

et al. 2014

Seminars in Vascular Surgery

View full text Add to dashboard Cite

“…In our previous study on 29 limbs of 23 patients, the TcPO 2 reached its peak level in the 4th week after PTA, and the TcPO 2 was lower than the peak level in the 5th and 6th weeks after PTA. However, the results of the current study indicated that the TcPO 2 continued to increase throughout the 6th week.…”

Section: Discussionmentioning

confidence: 72%

“…14 Another reason for the delay in reaching the peak level of tissue oxygenation may be transient oedema of the lower limb after PTA. [15][16][17] In our previous study on 29 limbs of 23 patients, the TcPO 2 reached its peak level in the 4th week after PTA, 18 and the TcPO 2 was lower than the peak level in the 5th and 6th weeks after PTA. However, the results of the current study indicated that the TcPO 2 continued to increase throughout the 6th week.…”

Section: Discussionmentioning

confidence: 82%

Comparison of perfusion values after percutaneous transluminal angioplasty according to the severity of ischaemia in the diabetic foot

Namgoong

Yang

Yoo

et al. 2018

International Wound Journal

View full text Add to dashboard Cite

Percutaneous transluminal angioplasty (PTA) is now more frequently used to improve tissue perfusion in ischemic diabetic feet. However, there are concerns about its feasibility and effectiveness in severely ischaemic feet. This study aimed to compare the perfusion values after PTA according to the ischaemic degree of diabetic feet. This study included 133 ischaemic diabetic feet. The foot transcutaneous oxygen pressure (TcPO2) and toe pressure were measured before the procedure and every second postoperative week for 6 weeks. The patients were divided into three groups according to ischaemic severity on the basis of TcPO2 and toe pressures. In the “severely ischaemic” group, the TcPO2 increased from 7.5 ± 4.9 to 40.3 ± 11.3 mm Hg (5.4‐fold) 6 weeks after the PTA (P < 0.001). The toe pressure increased from 8.5 ± 8.8 to 42.2 ± 19.3 mm Hg (5.0‐fold, P < 0.001). In the “mild” group, the TcPO2 increased from 35.4 ± 2.5 to 41.8 ± 12.4 mm Hg (1.2‐fold, P = 0.003), and the toe pressure increased from 45.7 ± 12.3 to 54.3 ± 31.3 mm Hg (1.2‐fold, P > 0.05). Results of the “intermediate” group were in between. The most severely ischaemic group had the most dramatic increase of tissue perfusion after PTA. As such, PTA can be an effective method for increasing tissue perfusion even in the severely ischaemic diabetic feet.

show abstract

“…In cases of chronic wounds, wound healing cannot often be achieved successfully because of the involvement of multiple factors (14, 15). One of main contributing factors for the non- or delayed healing wound is decreased function of the key cells for the wound healing including fibroblasts and keratinocytes.…”

Section: What Diseases Are Target Of Cell Therapy?mentioning

confidence: 99%

Cell Therapy for Wound Healing

2014

Self Cite

View full text Add to dashboard Cite

In covering wounds, efforts should include utilization of the safest and least invasive methods with goals of achieving optimal functional and cosmetic outcome. The recent development of advanced wound healing technology has triggered the use of cells to improve wound healing conditions. The purpose of this review is to provide information on clinically available cell-based treatment options for healing of acute and chronic wounds. Compared with a variety of conventional methods, such as skin grafts and local flaps, the cell therapy technique is simple, less time-consuming, and reduces the surgical burden for patients in the repair of acute wounds. Cell therapy has also been developed for chronic wound healing. By transplanting cells with an excellent wound healing capacity profile to chronic wounds, in which wound healing cannot be achieved successfully, attempts are made to convert the wound bed into the environment where maximum wound healing can be achieved. Fibroblasts, keratinocytes, adipose-derived stromal vascular fraction cells, bone marrow stem cells, and platelets have been used for wound healing in clinical practice. Some formulations are commercially available. To establish the cell therapy as a standard treatment, however, further research is needed. http://dx.doi. org/10.3346/jkms.2014.29.3.311 • J Korean Med Sci 2014 29: 311-319 We all experience our fair share of wounds during the course of our lives. The art and science of wound healing are complex and intriguing. During the past few decades, various wound healing technologies for promoting cell activity or minimizing scar formation have been developed and some of them are being actively used at present. The aim of this paper is to provide information on cell-based treatment options in clinical setting for healing of acute and chronic wounds. Keywords

show abstract

Effect of percutaneous transluminal angioplasty on tissue oxygenation in ischemic diabetic feet

Cited by 26 publications

References 22 publications

Contemporary assessment of foot perfusion in patients with critical limb ischemia

Contemporary assessment of foot perfusion in patients with critical limb ischemia

Comparison of perfusion values after percutaneous transluminal angioplasty according to the severity of ischaemia in the diabetic foot

Cell Therapy for Wound Healing

Contact Info

Product

Resources

About