Effect of pasteurization and storage on tetracycline levels in honey

Stability of tetracycline residues in honey

“…Molino et al 11 reported a 21 % decrease of the tetracycline level in honey after 30 days of storage at 20 °C, but the type of honey was not specified. Similar results were obtained by Čuláková et al 9 and Martel et al 8 In order to describe the degradation of tetracycline in the different types of honey, a first order kinetic model (1) was proposed:…”

Methods for the separation, preconcentration, and determination of tetracycline antibiotics

“…Liquid extraction from solid matrices seems the most common method for the separation of tetracy clines from the solid samples of food products. This method is used for the extraction of tetracycline anti biotics from meat [15][16][17][18][19][20][21][22][23][24][25][26][27], fish [27][28][29][30][31], eggs [18,27,32], and honey [33][34][35][36][37][38][39], and it is performed as follows: A weighed portion of a thoroughly ground solid sam ple is placed in a vessel for agitation, and a selected sol vent is added; the contents are stirred for a specified time (from several minutes to several hours). The phases are separated by filtration.…”

“…The phases are separated by filtration. Phosphate [16-18, 33, 38], citrate [19,29,33], hexamethylene tetramine [39], oxalate [20], and succinate [21,32] buffer solu tions and also the McIlvaine buffer solution [15,[34][35][36][37] are most frequently used as solvents. Furthermore, 5% trichloroacetic acid [23], a mixture of acetonitrile with a citrate buffer [28] and the McIlvaine buffer solution (60 : 40) [24,31], and the mixtures of metha nol with water (70 : 30) [30] and with 0.1 M succinic acid (50 : 50) [22,27] or acetonitrile are used [25,26].…”

“…SPE was used in the determination of tetracyclines in meat [15,19,21,22], fish [28-30, 45, 58], eggs [59,68], honey [34,35,37,69], and milk [33,[70][71][72][73][74][75][76][77][78][79][80]. In the case of milk, SPE was carried out in the majority of cases after the precipitation of proteins by trichloroacetic acid [70,75,77] or buffer solutions [33, 71-74, 79, 80].…”

Novel silver nanoparticle-enhanced fluorometric determination of trace tetracyclines in aqueous solutions

“…Because of their extensive use in infectious diseases therapy, several methods have been developed for antibiotic determination in aquatic environments. To date, there have been many techniques for the determination of TCs and their derivatives, such as UV [7], spectrophotometry [8][9][10], HPLC [11,12], capillary electrophoresis [13,14] and MS [15,16].…”