Effect of NaF and SnF<sub>2</sub>in Drinking Water on Hamster Dental Caries (Short Communication)

Tinanoff, Norman; Camosci, David

doi:10.1159/000260751

Caries Res

1984

DOI: 10.1159/000260751

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Effect of NaF and SnF₂in Drinking Water on Hamster Dental Caries (Short Communication)

Norman Tinanoff¹,

David Camosci²

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1986

1997

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Cited by 3 publications

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References 7 publications

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“…Although there are numerous studies in rats on the effect of fluoride in caries reduction, the majority have utilized large concentrations of fluoride [Larson et al, 1976;Tinanoff and Camosci, 1984;Afseth et al, 1984]. Generally, the concentrations are greater than that recommended for human consumption; conse quently, the development of an adequate animal model has been lacking.…”

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confidence: 99%

Effect of Low-Level Fluoride and Caries Incidence in Rats (Short Communication)

et al. 1989

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confidence: 99%

Effect of Low-Level Fluoride and Caries Incidence in Rats (Short Communication)

et al. 1989

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Caries and plaque inhibition in rats by five topically applied dentifrices

Guggenheim¹,

Lutz²,

Schmid³

1997

European J Oral Sciences

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The effectiveness of 5 different brands of dentifrices on caries and plaque were tested in rats in 2 experiments. 10 litters of rats each were infected with Streptococcus sobrinus OMZ-176 and Actinomyces viscosus Ny1. The rats were offered the diet 2000a containing either 40% of sucrose (study I) or 10% of sucrose (study II). The following products were tested topically: (1) H2O, (negative control); (2) chlorhexidine diacetate, (positive control); (3) Parodontax NF; (4) Meridol; (5) Colgate Total; (6) Mentadent C; (7) Dent Xpress. Comparisons with the water control in study I showed that plaque extent was decreased by chlorhexidine diacetate, Dent Xpress and by Mentadent C only. All fluoride-containing dentifrices tested reduced caries. In study II, comparisons with the water control showed that plaque extent was reduced by chlorhexidine diacetate, Parodontax, Meridol, Dent Xpress and by Mentadent C. All dentifrices reduced caries, however, the incidence was low. These 2 studies confirm that fluorides incorporated in dentifrices decrease dental caries in the rat. Differences in the effectiveness of caries inhibition between the 5 dentifrices could not be explained either by the form of fluoride utilized or by the antimicrobials added. Rather, the performance of a given dentifrice depended upon the concerted action of the particular ingredients. It appears that the effect of antiplaque agents should be evaluated in the rat model using a diet containing sucrose at a low level.

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Effects of fluoridated drinking water on rat enamel fluoride and its caries development.

Anbe¹

1986

J Dent Hlth

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Abstract:The aim of the present study was to investigate the effect of fluoridated drinking water on the fluoride content of the enamel and on the development of dental caries in the rat. Twenty-one-dayold Sprague-Dawly rats were subjected to a 4-week pre-caries test period during which they were fed a non cariogenic diet and given distilled water containing 0 ppm, 10 ppm, or 50 ppm fluoride concentration as sodium fluoride. After this period, each group was fed a cariogenic diet and given distilled water The results of this study strongly suggest that enamel-bound fluorides provided prior to a cariogenic challenge conferred protection from caries, especially, from sulcal lesions.

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Effect of NaF and SnF₂in Drinking Water on Hamster Dental Caries (Short Communication)

Cited by 3 publications

References 7 publications

Effect of Low-Level Fluoride and Caries Incidence in Rats (Short Communication)

Effect of Low-Level Fluoride and Caries Incidence in Rats (Short Communication)

Caries and plaque inhibition in rats by five topically applied dentifrices

Effects of fluoridated drinking water on rat enamel fluoride and its caries development.

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Effect of NaF and SnF2in Drinking Water on Hamster Dental Caries (Short Communication)

Cited by 3 publications

References 7 publications

Effect of Low-Level Fluoride and Caries Incidence in Rats (Short Communication)

Effect of Low-Level Fluoride and Caries Incidence in Rats (Short Communication)

Caries and plaque inhibition in rats by five topically applied dentifrices

Effects of fluoridated drinking water on rat enamel fluoride and its caries development.

Contact Info

Product

Resources

About

Effect of NaF and SnF₂in Drinking Water on Hamster Dental Caries (Short Communication)