Effect of inflammation on cytokine levels and bone remodelling markers in peri-implant sulcus fluid: A preliminary report

“…Others have identified that a balance of inflammatory‐ and osteoclastogenesis‐related molecules locally produced could play an important role in the development of inflammatory peri‐implant lesions (Güncü et al. ).…”

Section: Discussionmentioning

confidence: 99%

Cytokine expression in peri‐implant crevicular fluid in relation to bacterial presence

Renvert

Widén

Persson

2015

J Clinic Periodontology

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“…Güncü et al22 in 2012 evaluated the effect of inflammation on the level of cytokines in the crevicular fluid around implants. They divided specimens into two groups: with and without inflammation.…”

Section: Discussionmentioning

confidence: 99%

Assessment of interleukin-1beta and interleukin-6 in the crevicular fluid around healthy implants, implants with peri-implantitis, and healthy teeth: a cross-sectional study

Yaghobee

Khorsand

Ghohroudi

et al. 2014

J Korean Assoc Oral Maxillofac Surg

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ObjectivesThis study aimed to assess and compare the levels of interleukin-1beta (IL-1β) and interleukin-6 (IL-6) in the crevicular fluid around healthy implants, implants with peri-implantitis, and healthy teeth.Materials and MethodsThis study evaluated 16 dental implants in 8 patients (4 males and 4 females). These patients had at least one healthy implant and one implant with peri-implantitis next to healthy teeth. The crevicular fluid was collected using absorbent cones and transferred to the laboratory. Specimens were evaluated by ELISA for interleukin levels. Data were analyzed using repeated measures ANOVA and Bonferroni tests (P<0.05).ResultsLevels of IL-1β in the crevicular fluid around implants with peri-implantitis were significantly higher than around healthy implants (P=0.002); the latter was significantly higher than around healthy teeth (P=0.015). A significant difference was found in the level of IL-6 in the crevicular fluid around implants with peri-implantitis and healthy implants (P=0.049) and also between implants with peri-implantitis and healthy teeth (P<0.001).ConclusionWithin the limitations of this study, significant differences exist in the levels of IL-1β and IL-6 in the crevicular fluid of implants with peri-implantitis, healthy implants, and healthy teeth. More studies with larger sample sizes in different populations are necessary.

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Effect of inflammation on cytokine levels and bone remodelling markers in peri-implant sulcus fluid: A preliminary report

Cited by 48 publications

References 29 publications

Can Peri‐Implant Crevicular Fluid Assist in the Diagnosis of Peri‐Implantitis? A Systematic Review and Meta‐Analysis

Can Peri‐Implant Crevicular Fluid Assist in the Diagnosis of Peri‐Implantitis? A Systematic Review and Meta‐Analysis

Cytokine expression in peri‐implant crevicular fluid in relation to bacterial presence

Assessment of interleukin-1beta and interleukin-6 in the crevicular fluid around healthy implants, implants with peri-implantitis, and healthy teeth: a cross-sectional study

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