Effect of Incorporating Nano-Pearl and Nano-Seashell Particles into Fluoride-based Pits and Fissure Sealant on Enamel Remineralization of Permanent Extracted Molars: An In Vitro Study.

Aidaros, Nawal; Kamh, Raghda

doi:10.21608/adjc.2021.80816.1101

Cited by 7 publications

(6 citation statements)

References 26 publications

(31 reference statements)

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“…Moreover, this may be linked with the more porous primary enamel and its higher proclivity for dissolution. On the other hand, this result was inconsistent with Aidaros & Kamh, [ 48 ] who found a reduction of carbon ion percentage after the application of fluoride-based pits and fissures sealants containing nano-seashell & nano-pearl compared to the percentage increase in the control group.…”

Section: Discussioncontrasting

confidence: 80%

Effect of N-Acetylcysteine on initial Carious Enamel Lesions in primary teeth: an In-vitro study

2023

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Background Dental caries initiates with non-cavitated enamel lesions as the first stage. The cariogenic potential of N-Acetylcysteine (NAC) may be due to its usage frequency and form. This study aimed to evaluate the impact of exposure time of NAC on initial enamel caries-like lesions in primary teeth by assessing the morphological alteration using a scanning electron microscope (SEM) and mineral content using energy dispersive x-ray spectroscopy (EDX). Methods Forty primary incisor teeth were randomly divided into 4 groups S, S1, S2, and S3 (10 specimens/group). Teeth crowns were cut from their roots and inserted into an acrylic mold with its buccal surface directed upward. Centrally isolated enamel window (2 × 2 mm) on the tooth was done. Ten specimens were selected to evaluate normal enamel while the remaining thirty specimens were immersed in demineralizing solution for 96 h to produce enamel caries-like lesions. PH cycling was performed by immersing each tooth sample in 20 mL of demineralizing solution for 3 h then, preserved for the remaining day hours in 10 ml of artificial saliva interspersed with treatments applications with 10 ml NAC for 10 min twice a day for one- or three-months different treatment modalities. Thermocycling was done for all specimens then they were subjected to SEM and EDX analysis. ANOVA and Bonferroni post hoc tests were utilized in data analysis. Results In teeth treated by NAC for 3 months (group-S3), SEM images showed severe loss of enamel architecture with large NAC deposits detected. A meaningful difference was observed among different groups concerning calcium, phosphorus, fluoride, ca/P ratio, carbon, nitrogen, and oxygen contents (P < 0.05). Conclusion NAC had a detrimental impact on enamel caries-like lesions in human primary teeth.

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Section: Discussioncontrasting

confidence: 80%

Effect of N-Acetylcysteine on initial Carious Enamel Lesions in primary teeth: an In-vitro study

2023

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“…Artificial saliva was also used as a storage medium for all groups to mimic saliva's capacity to remineralize as it contains inorganic electrolytes (calcium, phosphorus, and fluoride) that are crucial players in the remineralization process 45,46 .…”

Section: Discussionmentioning

confidence: 99%

Biomimetic Remineralization of Early Human Enamel Carious Lesions With Different Commercially Available Herbal Nanohydroxyapatite Toothpastes: An in-Vitro Comparative Evaluation

El-Bedewy,

Zayed,

Hussein

2024

Egyptian Dental Journal

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Objectives: To compare the remineralizing capability of three readily available commercial herbal nanohydroxyapatite toothpastes on early human enamel carious lesions using a PH cycling model. Materials & Methods:Thirty-two caries-free extracted human maxillary central incisors were sectioned cervically about 2mm below cementoenamel junction. Carious-like lesions were induced by immersing the crowns of the samples in acidified gel for 7 days. Samples were then divided into 4 groups (8 samples each); in group I, samples were brushed with BOKA Ela Mint toothpaste, in group II, they were brushed with BOKA Coco Ginger toothpaste, in group III, samples were brushed with BOKA Lemon Lavender toothpaste, and in group IV (control) samples were stored in artificial saliva. The brushing time was 2 minutes twice daily. Using artificial saliva, a pH cycling model was used to simulate remineralization for 45 days. The enamel surfaces of samples were subjected to surface microhardness (SMH) test with a Vickers hardness tester, and the average Ca level was analyzed using energy-dispersive X-ray spectroscopy (EDX). The measurements were done before and after demineralization, and after remineralization. One-way ANOVA, Tukey's test, and paired T-test (P<0.05) were used for analyzing the data.Results: All treatments effectively remineralized the early human enamel carious lesions. BOKA Ela Mint toothpaste showed the maximum increase in SMH and Ca level deposition, while BOKA Lemon Lavender toothpaste showed the lowest. Conclusion:Nanohydroxyapatite toothpastes may be the optimal for bio mimetic remineralization of early human enamel carious lesions.

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“…The demineralizing solution used in this study of pH 4.4 to simulate the pH drop that happens in the oral cavity; as it can cause enamel dissolution and demineralization (17) . Artificial saliva was used as a storage medium for all experimental and negative control teeth to simulate the remineralizing capacity of human saliva (31) , as it contains inorganic electrolytes (calcium, phosphorus, and fluoride) that are important participants in the remineralization process (32) . All specimens were subjected to enamel surface microhardness test (Vickers Microhardness Tester) at baseline, after demineralization and after 7 days of remineralization with different concentrations of stevia and green tea, fluoride mouthwash (positive control) as well as the specimens stored in the artificial saliva without any treatment (negative control).…”

Section: Discussionmentioning

confidence: 99%

Remineralization and Antibacterial Efficacy of Different Concentrations of Aqueous Stevia extract and green tea Solutions in Comparison with Fluoride-based Mouthwash on Initial Enamel Carious Lesion- An Invitro Study

Kamh

2022

Egyptian Dental Journal

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Aim: This in vitro study evaluated and compared the remineralizing potential of different herbal extracts aqueous solutions versus fluoride mouthwash by assessing the enamel surface microhardness and antimicrobial susceptibility. Materials and methods:Sixty extracted premolars were used in this study and equally distributed into six groups of 10 teeth each. Group A: teeth treated with 0.5% stevia aqueous solution; Group B: teeth treated 5% stevia aqueous solution; Group C: teeth treated with 0.5% green tea aqueous solution; Group D: teeth treated with 5% green tea aqueous solution; Group E: teeth treated with Fluoride mouthwash as a positive control group; negative control group: teeth not subjected to any treatment and stored in artificial saliva. The teeth of each group were subjected to microhardness assessment at baseline, after 48 hours demineralization, and after 7 days remineralization phase. The antibacterial activities of herbal extracts and fluoride against S. mutants and Lactobacillus were quantitatively measured by an antimicrobial susceptibility test.Results: After 7 days of treatment, the highest mean value was recorded in group D (282.69 Kgf/mm 2 ) with the least mean value recorded in the control group (168.66 Kgf/mm 2 ). The difference between groups was statistically significant (p= 0.001). The 5% green tea extract showed the highest mean value of inhibition zone (10.6 mm) against S. mutants' while fluoride showed the highest mean value of inhibition zone (14.6 mm) against the Lactobacillus. Conclusion:An aqueous solution of 5 % green tea is an effective remineralizing agent with antimicrobial activity against S. mutans.

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Effect of Incorporating Nano-Pearl and Nano-Seashell Particles into Fluoride-based Pits and Fissure Sealant on Enamel Remineralization of Permanent Extracted Molars: An In Vitro Study.

Cited by 7 publications

References 26 publications

Effect of N-Acetylcysteine on initial Carious Enamel Lesions in primary teeth: an In-vitro study

Effect of N-Acetylcysteine on initial Carious Enamel Lesions in primary teeth: an In-vitro study

Biomimetic Remineralization of Early Human Enamel Carious Lesions With Different Commercially Available Herbal Nanohydroxyapatite Toothpastes: An in-Vitro Comparative Evaluation

Remineralization and Antibacterial Efficacy of Different Concentrations of Aqueous Stevia extract and green tea Solutions in Comparison with Fluoride-based Mouthwash on Initial Enamel Carious Lesion- An Invitro Study

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