Effect of fructose-reduced diet in patients with irritable bowel syndrome, and its correlation to a standard fructose breath test

Berg, Leif Kyrre; Fagerli, Erik; Martinussen, Marit; Myhre, Arnt-Otto; Florholmen, Jon; Goll, Rasmus

doi:10.3109/00365521.2013.812139

Cited by 40 publications

(57 citation statements)

References 18 publications

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“…The study therefore offered no evidence that patients who reported symptoms produced more colonic gas than those who did not. Those patients with a higher peak in breath hydrogen were no more likely to report symptoms with inulin or fructose, in agreement with other studies suggesting that the utility of a breath test to predict response to dietary fructose exclusion is limited 33,34 . An alternative hypothesis would be that, as has been shown with lactose malabsorption 35 , the patients with symptoms had a lower sensory threshold for reporting.…”

Section: Discussionsupporting

confidence: 78%

Colon Hypersensitivity to Distension, Rather Than Excessive Gas Production, Produces Carbohydrate-Related Symptoms in Individuals With Irritable Bowel Syndrome

et al. 2017

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Section: Discussionsupporting

confidence: 78%

Colon Hypersensitivity to Distension, Rather Than Excessive Gas Production, Produces Carbohydrate-Related Symptoms in Individuals With Irritable Bowel Syndrome

et al. 2017

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“…As previously described [11] , the study was designed with a pre-registration period of 2 wk in which the patients followed their individual habitual IBS diet (HID). The patients were then randomized without stratification to continue HID with or without additional FRD (< 2 g fructose per meal) for 12 wk.…”

Section: Methodsmentioning

confidence: 99%

“…The study outline has been published earlier [11] . In brief, during the period July 2008 and July 2011, patients who met the Rome Ⅱ criteria for diagnosis were recruited.…”

Section: Enrolment and Patient Flowmentioning

confidence: 99%

“…These include factors such as colonization by nonhydrogen-producing bacteria and gastrointestinal dysmotility [5] . In a recently published report we have described a discrepancy between the FBT and the effects of a fructose-reduced diet (FRD) [11] . Due to the lack of an accurate and valid test for diagnosing FM, there is an increasing interest to use selfreported responses to FRD as a diagnostic tool for FM.…”

Section: Introductionmentioning

confidence: 98%

“…This is a follow-up report of the open multicenter randomized controlled trial, Fructose Malabsorption in Northern Norway [11] .…”

Section: Introductionmentioning

confidence: 99%

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Self-reported dietary fructose intolerance in irritable bowel syndrome: Proposed diagnostic criteria

Berg¹

2015

WJG

Self Cite

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AIM: To study the criteria for self-reported dietary fructose intolerance (DFI) and to evaluate subjective global assessment (SGA) as outcome measure. METHODS:Irritable bowel syndrome (IBS) patients were randomized in an open study design with a 2 wk run-in on a habitual IBS diet, followed by 12 wk with/without additional fructose-reduced diet (FRD). Daily registrations of stool frequency and consistency, and symptoms on a visual analog scale (VAS) were performed during the first 4 wk. SGA was used for weekly registrations during the whole study period. Provocation with high-fructose diet was done at the end of the registration period. Fructose breath tests (FBTs) were performed. A total of 182 subjects performed the study according to the protocol (88 FRD, 94 controls). RESULTS:We propose a new clinically feasible diagnostic standard for self-reported fructose intolerance. The instrument is based on VAS registrations of symptom relief on FRD combined with symptom aggravation upon provocation with fructose-rich diet. Using these criteria 43 of 77 patients (56%) in the present cohort of IBS patients had self-reported DFI. To improve the concept for clinical evaluation, we translated the SGA scale instrument to Norwegian and validated it in the context of the IBS diet regimen. The validation procedures showed a sensitivity, specificity and κ value for SGA detecting the self-reported DFI group by FRD response within the IBS patients of 0.79, Randomized Controlled Trial Self

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Chemical components of Fu brick tea and its potential preventive effects on metabolic syndrome

Li,

Dai,

Zhang

et al. 2023

Food Science & Nutrition

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As living standards advance, an escalating emphasis is placed on health, particularly in relation to prevalent chronic metabolic disorders. It is necessary to explore safe and effective functional foods or drugs. Fu brick tea (FBT) is a kind of dark tea fermented by fungi. The extracts are rich in compounds that can effectively relieve metabolic diseases such as hyperglycemia and hyperlipidemia, protect the liver, improve human immunity, enhance antioxidant activity, and regulate intestinal flora. This paper summarizes the biological activities and mechanisms of the extracts, polysaccharides, and small molecular compounds of FBT, which provides a certain theoretical basis for the rational, systematic, comprehensive development and utilization of the FBT resources. It is expected to develop and apply these active substances in health care products and natural medicines and provide more beneficial and diversified FBT products for human beings.

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Effect of fructose-reduced diet in patients with irritable bowel syndrome, and its correlation to a standard fructose breath test

Abstract: VAS measures yield reliable symptom evaluation in dairy registrations of IBS. FRD improves symptom scores in IBS patients independent of results from the FBT.

Cited by 40 publications

References 18 publications

Colon Hypersensitivity to Distension, Rather Than Excessive Gas Production, Produces Carbohydrate-Related Symptoms in Individuals With Irritable Bowel Syndrome

Colon Hypersensitivity to Distension, Rather Than Excessive Gas Production, Produces Carbohydrate-Related Symptoms in Individuals With Irritable Bowel Syndrome

Self-reported dietary fructose intolerance in irritable bowel syndrome: Proposed diagnostic criteria

Chemical components of Fu brick tea and its potential preventive effects on metabolic syndrome

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