Effect of dietary bile acids on growth, body composition, lipid metabolism and microbiota in grass carp (Ctenopharyngodon idella)

Abstract

To investigate the effects of dietary bile acids (BA) on growth and metabolism of lipid in grass carp (Ctenopharyngodon idella, C. idella) at high dietary lipid level, a basal diet (50 g kg -1 lipid, 5L group) was supplemented with 20 g kg -1 soybean oil (70 g kg -1 lipid, 7L group); then, 0.06 g/kg BA was added in 7L diet to form the third diet (7L+BA group). The 96 C. idella (69.86 ± 6.24 g) were divided into three groups (duplicate per group) and fed three diets, respectively, for 8 weeks, and then, growth and lipid metabolism were determined. Results showed that growth of fish in 7L+BA group was significantly higher than 5L and 7L groups. The lipid level in whole body, hepatopancreas and muscle of grass carp in 7L+BA group were significantly lower than 7L group.Relative expression of lipid catabolism genes in hepatopancreas and muscle of 7L+BA group was significantly higher than 5L group. The amount of microbiota in intestine of fish in 7L+BA group was significantly higher than the other two groups. The present results indicated that BA in 7L diet improved growth of fish by increasing protein synthesizing, decreasing lipid content in fish body and by regulating amount of microbiota in intestine of fish. K E Y W O R D S adipose triglyceride lipase, fatty acid synthase, growth performance, intestinal microbiota, lipid accumulation, protein deposition How to cite this article: Zhou JS, Chen HJ, Ji H, et al. Effect of dietary bile acids on growth, body composition, lipid metabolism and microbiota in grass carp (Ctenopharyngodon idella). Aquacult Nutr. 2018;24:802-813.

Synergism of Dietary Co-Supplementation with Lutein and Bile Salts Improved the Growth Performance, Carotenoid Content, Antioxidant Capacity, Lipid Metabolism, and Lipase Activity of the Marbled Spinefoot Rabbitfish, Siganus rivulatus

“…Dietary supplementation with BS improved antioxidant systems, liver function, and histological structure and had an anti-inflammatory effect in juvenile black sea bream, Acanthopagrus schlegelii [30]. In addition, dietary supplementation with BS improved growth performance, feed utilization, and antioxidant systems of European seabass, Dicentrarchus labrax [2], grass carp, Ctenopharyngodon idella [31], and Nile tilapia, Oreochromis niloticus [32]. BS supplementation in a soybean meal-based diet improved the growth performance and feed utilization in rainbow trout, Oncorhynchus mykiss [33].…”

Effects of Dietary Lysophosphatidylcholine on Growth Performance and Lipid Metabolism of Juvenile Turbot

“…In recent years, they are also being more and more frequently used in farmed fish, typically bile acids [7,8]. The positive effects of bile acids on growth and lipid metabolism of farmed fish have been reported in a number of studies [9][10][11][12][13][14][15][16][17], including a recent study of ours with a marine teleost, tiger puffer (Takifugu rubripes) [18]. However, another effective emulsifier, lysophospholipid (mostly lysolecithin), which has been demonstrated to have high efficiency in enhancing dietary lipid utilization in terrestrial animals [19][20][21][22][23][24][25], has not been well investigated in farmed fish.…”

Effects of bile acids on the growth performance, lipid metabolism, non‐specific immunity and intestinal microbiota of Pacific white shrimp ( Litopenaeus vannamei )

“…It has been clarified that bile acids could take part in the regulation of the antioxidant defence (Ljubuncic et al, 2000;Mitsuyoshi et al, 1999) and immune response (D'Aldebert et al, 2009) of mammals. Previous research also proved that dietary supplementation of bile acids could exert obviously beneficial effects on fish, including the better growth performance, promoted feed conversation ratio, enhanced liver function, higher digestive enzyme activity and alleviated stress response (Alam et al, 2001;Ding et al, 2020;Guo et al, 2020;Jiang et al, 2018;Liao et al, 2020;Maita et al, 1996;Zhou et al, 2018). Whereas, effects of dietary bile acids on invertebrates including shrimp without the ability to synthesize bile acids de novo have not been reported (Teshima, 1971), and whether bile acids could regulate the detoxification system, antioxidant defence and immune response of shrimp is totally unknown.…”