Effect of Body Mass Index on Lipid Profile of Type 2 Diabetic Patients at An Urban Tertiary Hospital In Nigeria

Omotoye, Funmilayo Esther; Fadupin, Grace T.

doi:10.9790/0853-1509086570

Cited by 6 publications

(4 citation statements)

References 25 publications

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“…The comparison made between diabetic male and females in the previous study found that most of the parameters were statistically insignificant, with p-values of greater than 0.05 [24]. This is in line with this study whereby there were several insignificant statistical differences between diabetic males and females in some instances (Table 3), with the highest in TC.…”

Section: Discussionsupporting

confidence: 83%

“…This study was comparable to other studies in African diabetic patients, with similar results being reported in a study at Kenyatta National Hospital, Nairobi, which showed that over 70% of the participants had a total cholesterol level greater than 4.2 mmol/L, LDL greater than 2.6 mmol/L, and an HDL level lower than 1.00 mmol/L. Only a few (28.3% males and 32.2% females) of the participants had a triglyceride level greater than 1.7 mmol/L [11,23,24]. In this study, a prevalence of 89% of dyslipidaemia in all the T2DM patients, 56% with high cholesterol of 5.1-8.1 mmol/L, was observed, with 64% having hypertriglycemia of 1.72-8.63 mmol/L, while 61% were affected by a high LDL cholesterol of 3.1-5.6 mmol/L.…”

Section: Discussionmentioning

confidence: 99%

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Prevalence of Dyslipidaemia among Type 2 Diabetes Mellitus Patients in the Western Cape, South Africa

Omodanisi

Tomose

Okeleye

et al. 2020

IJERPH

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Dyslipidaemia, an irregular aggregate of lipids in the blood is common in diabetes and cardiovascular disease sufferers. A cross-sectional study on the prevalence of dyslipidaemia was performed among type 2 diabetes mellitus (T2DM) patients in the Western Cape, South Africa. Patients (n = 100) that participated in the study were within the age range of 19–68 years, of whom 89% were observed to have serum lipid abnormalities. Out of the 100 patients, 56%, 64%, 61%, and 65% were recorded to have high total cholesterol (TC), hypertriglycemia, increased low-density lipoproteins cholesterol (LDL-C), and reduced high-density lipoproteins cholesterol (HDL-C), respectively. In male diabetic patients, a marked prevalence of (94%) dyslipidemia was noted, of which 52% were affected by high TC (5.3–7.9 mmol/L), with 70% having a high level of triglyceride (TG) [1.72–7.34 mmol/L], while 60% had a high LDL-C (3.1–5.5 mmol/L), including 78% with low HDL-C (0.7–1.1 mmol/L). In comparison, 84% of diabetic females had dyslipidemia, with high TC (5.1–8.1 mmol/L), hypertriglycemia (1.73–8.63 mmol/L), high LDL-C (3.1–5.6 mmol/L), and low levels of HDL-C (0.8–1.1 mmol/L) affecting 60%, 58%, 62%, and 52% of the patients, respectively. This study showed the importance of screening and the regular surveillance of dyslipidaemia in T2DM patients as there is a paucity of data on it in Africa.

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Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 99%

Prevalence of Dyslipidaemia among Type 2 Diabetes Mellitus Patients in the Western Cape, South Africa

Omodanisi

Tomose

Okeleye

et al. 2020

IJERPH

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“…However, our study emphasizes the diagnosis of dysglycaemia in patients with cardiovascular disease, which was not considered in that study. Another non-European study also found a weak negative correlation of HDL-C with BMI [26]. The correlation of these factors has been described previously by researchers, however they did not identify them as factors that we should particularly consider when discharging cardiac patients at risk of dysglycaemia from hospital.…”

Section: Discussionmentioning

confidence: 57%

Undiagnosed Diabetes and Prediabetes in Patients with Chronic Coronary Syndromes—An Alarming Public Health Issue

Drobek

Sowa

Jankowski

et al. 2021

JCM

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Dysglycemia is a public health challenge for the coming decades, especially in patients with chronic coronary syndromes (CCS). We want to assess the prevalence of undiagnosed diabetes mellitus (DM) and prediabetes, as well as identify factors associated with the development of dysglycaemia in patients with CCS. In total, 1233 study participants (mean age 69 ± 9 years), who, between 6 and 18 months earlier were hospitalized for acute coronary syndrome or elective revascularization, were examined (71.4% men). The diagnosis of DM, impaired fasting glucose (IFG), impaired glucose tolerance (IGT) have been made according to World Health Organization (WHO) criteria. Based on the oral glucose tolerance test (OGTT) results, DM has been newly diagnosed in 28 (5.1%, mean age 69.9 ± 8.4 years) patients, 75% were male (n = 21). Prediabetes has been observed in 395 (72.3%) cases. IFG was found in 234 (42.9%) subjects, 161 (29.5%) individuals had IGT. According to multinomial logistic regression, body mass index (BMI) and high-density lipoprotein cholesterol (HDL-C) should be considered when assessing risk of development of dysglycaemia after discharge from the hospital. Among people with previously diagnosed DM, a significantly higher percentage were willing to change their lifestyles after the index event compared to other patients. Patients with chronic coronary syndromes suffer a very high frequency of dysglycaemia. Most patients with chronic coronary syndromes, especially those with high BMI or low HDL-C, should be considered for screening for dysglycemia using OGTT within the first year after hospitalization. A higher percentage of patients who were aware of their diabetic status changed their lifestyles, which added the benefit of timely diagnosis and treatment of diabetes.

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“…Association of lipid profile is reported with lifestyle, intra-abdominal adiposity, obesity and BMI (Omotoye and Fadupin, 2016). But the South Asian population is found to have a higher abdominal obesity as compared to the population in the European regions; therefore, the susceptibility towards certain types of diseases, such as diabetes and so as the lipid abnormalities may vary across these regions even if the BMI values are comparable (Patel et al, 2001 and WHO, 2000).…”

Section: Introductionmentioning

confidence: 99%

A structural equation modeling examining the influence of body mass index on the lipid profile of type II diabetes patients

2022

Nutr Health

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Background: High Body Mass Index (BMI) has a two times greater risk of developing type II diabetes compared to low BMI. The results showed that general obesity had a risk of 2.24 times while abdominal obesity had a risk of 2.44 times for the occurrence of diabetes. Aim: Based on the background described, the researcher was interested in examining the influence of BMI on the lipid profile of type II diabetes patients. Methods: A considerably large sample of 500 type II diabetes patients who attended the outpatient department of Endocrinology wing of NIMS Medicity (NICER-Noorul Islam Centre for Endocrinology Research), Kerala, India were selected to the macrosample pool following purposive random sampling method. Height and weight of the patients were taken following standard methods and BMI of the patients was computed. Biochemical investigations such as their lipid profile along with Fasting, Post Prandial Blood Glucose values and HbA1C were obtained from patients’ medical records. Finally, the hypothesized model was developed and tested by Structural Equation Modeling (SEM) technique using SPSS AMOS 22.0. Results: The results show that height and weight highly influenced the BMI, among which weight, as shown by Standardized Regression Weights (SRW) Estimate- 1.102, Statistically Significant) influenced more than height (SRW Estimate:-0.683, Statistically Significant), weight had a positive influence, whereas height had a negative influence in selected Type II Diabetes patients. The model could not establish any relationship between BMI and lipid profile (SRW Estimate:-0.037, Statistically not Significant). Conclusion: The findings suggest that in diabetes patients increase in BMI alone does not lead to any alterations in their lipid profile.

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Effect of Body Mass Index on Lipid Profile of Type 2 Diabetic Patients at An Urban Tertiary Hospital In Nigeria

Cited by 6 publications

References 25 publications

Prevalence of Dyslipidaemia among Type 2 Diabetes Mellitus Patients in the Western Cape, South Africa

Prevalence of Dyslipidaemia among Type 2 Diabetes Mellitus Patients in the Western Cape, South Africa

Undiagnosed Diabetes and Prediabetes in Patients with Chronic Coronary Syndromes—An Alarming Public Health Issue

A structural equation modeling examining the influence of body mass index on the lipid profile of type II diabetes patients

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