Effect of ascorbic acid on morphology of post-thawed human adipose-derived stem cells

Wahyuningsih, Komang Ardi; Karina, Karina; Rosadi, Imam; Rosliana, Iis; Subroto, Wismo Reja

doi:10.21037/sci-2020-011

Cited by 7 publications

(4 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Ishikawa et al reported that ascorbic acid-induced upregulation of type I collagen production; α2β1 integrin (a major receptor of type I collagen) and alkaline phosphatase activity on periodontal ligament cells on the early osteoblastic differentiation of periodontal ligament cells [ 58 ]. The osteoblast differentiation of stem cells has potential clinical applications in enhancing implant osseointegration and sinus augmentation [ 2 , 3 , 4 , 59 , 60 , 61 , 62 ].…”

Section: Discussionmentioning

confidence: 99%

Effect of Ascorbic Acid on Differentiation, Secretome and Stemness of Stem Cells from Human Exfoliated Deciduous Tooth (SHEDs)

Bhandi

Alkahtani

Mashyakhy

et al. 2021

JPM

View full text Add to dashboard Cite

Stem cells from human exfoliated deciduous teeth (SHEDs) are considered a type of mesenchymal stem cells (MSCs) because of their unique origin from the neural crest. SHEDs can self-renewal and multi-lineage differentiation with the ability to differentiate into odontoblasts, osteoblast, chondrocytes, neuronal cells, hepatocytes, adipocytes, etc. They are emerging as an ideal source of MSCs because of their easy availability and extraordinary cell number. Ascorbic acid, or vitamin C, has many cell-based applications, such as bone regeneration, osteoblastic differentiation, or extracellular matrix production. It also impacts stem cell plasticity and the ability to sustain pluripotent activity. In this study, we evaluate the effects of ascorbic acid on stemness, paracrine secretion, and differentiation into osteoblast, chondrocytes, and adipocytes. SHEDs displayed enhanced multifaceted activity, which may have applications in regenerative therapy.

show abstract

Section: Discussionmentioning

confidence: 99%

Effect of Ascorbic Acid on Differentiation, Secretome and Stemness of Stem Cells from Human Exfoliated Deciduous Tooth (SHEDs)

Bhandi

Alkahtani

Mashyakhy

et al. 2021

JPM

View full text Add to dashboard Cite

show abstract

“…This potential effect is similar to platelet-rich plasma supplementation in adipose-derived stem cells (ADSCs) media that increased the rate of cell proliferation as well as their doubling time (15,16). In addition, ascorbic acid that has high anti-oxidant activity showed increased proliferation (15), induced chondrogenic and osteogenic differentiation (17,18), and delayed aging process (19).…”

Section: Discussionmentioning

confidence: 87%

The Effectivity of Honey Bee Towards Mesenchymal Stem Cells Proliferation: A Systematic Review

et al. 2023

Self Cite

View full text Add to dashboard Cite

Context: Using stem cells in the medical field as a regenerative therapy to repair damaged tissue is popular nowadays. Honey contains antioxidant activity, minerals, sugars, and other ingredients supporting wound healing and mature tissue regeneration. However, using honey to induce stem cell proliferation still lacks studies. In this review, we would like to do a systematic review to confirm the effectiveness of honey bees towards stem cell proliferation in both in vitro and in vivo treatment. Objectives: This study used all previous studies that included honey bees and stem cells in both in vitro and in vivo treatments. The search was performed on July 30th – 31st, 2021, and obtained 21 articles, of which 16 were excluded and the rest were screened. One screened literature was out of the limit; thus, five articles matched the terms. Relevant studies were retrieved from PubMed and the Cochrane Library. Data Methods: According to in vitro studies, honey of Trigona spp. increases the proliferation rate of dental pulp stem cells (DPSCs). Honey is effective for wound healing and stem cell regeneration. Meanwhile, in vivo studies showed honey increases the regeneration of malnutrition ovary failure. Results: According to in vitro studies, honey of Trigona spp. increases the proliferation rate of DPSCs. Honey is effective for wound healing and stem cell regeneration. Meanwhile, in vivo studies showed honey increases the regeneration of malnutrition ovary failure Conclusions: In conclusion, honey positively affects stem cell proliferation and can be used to supplement stem cells.

show abstract

“…Salah satunya dengan mengamati tingkat keparahan gejala penyakit pada daun dan identifikasi penyakitnya. Software ImageJ telah banyak dikembangkan untuk berbagai penelitian di bidang Biologi termasuk menganalisis serangan penyakit pada tanaman (Karina et al, 2019;Wahyuningsih et al, 2020;Zaelani, et al, 2020). Selain itu, terdapat software Plantix yang dapat digunakan untuk mengindentifikasi penyakit pada tanaman berbasis foto (Goncharov et al, 2020).…”

Section: Pendahuluanunclassified

Analisis Tingkat Keparahan Penyakit pada Daun Tanaman Pangan dengan Menggunakan Software ImageJ dan Plantix

Rosadi

Ayuni

Nurcahyani

et al. 2022

B : JIB

View full text Add to dashboard Cite

Plant disease is the physiological process that causes them to become abnormal. Plant diseases attack vegetative organs in the form of roots, stems, and leaves or generative organs of these plants. Plants become sick due to fungi, bacteria, or viruses that cause many symptoms of disease in plants, such as yellow spots, infection, and nitrogen deficiency (N). The purpose of this case study was to determine the severity of disease on gourds leaves (Lagenaria siceraria), bitter melon leaves (Momordica charantia), cassava leaves (Manihot esculenta), purple eggplant leaves (Solanum melongena), and terung pipit leaves (Solanum torvum) by using the Plantix software and ImageJ software methode. Based on the results of this case study, it was found that the severity of disease using ImageJ software on gourds leaves (4.56%), bitter melon leaves (1.93%), cassava leaves (8.49%), purple eggplant leaves (49.45%) and terung pipit leaves (14.88%) which are generally food crops are caused by viruses and fungiand based on the results of the Plantix software data, the causes of gourds leaves, bitter melon leaves, cassava leaves, purple eggplant leaves and terung pipit leaves respectively are caused by downy mildew, fungus, whitefly, leaf spot algae and leafhoppers.

show abstract

Effect of ascorbic acid on morphology of post-thawed human adipose-derived stem cells

Cited by 7 publications

References 24 publications

Effect of Ascorbic Acid on Differentiation, Secretome and Stemness of Stem Cells from Human Exfoliated Deciduous Tooth (SHEDs)

Effect of Ascorbic Acid on Differentiation, Secretome and Stemness of Stem Cells from Human Exfoliated Deciduous Tooth (SHEDs)

The Effectivity of Honey Bee Towards Mesenchymal Stem Cells Proliferation: A Systematic Review

Analisis Tingkat Keparahan Penyakit pada Daun Tanaman Pangan dengan Menggunakan Software ImageJ dan Plantix

Contact Info

Product

Resources

About