Effect of aflatoxin B1 on development of Drosophila melanogaster (Diptera)

The protective effect of hydrated sodium calcium aluminosilicate against the adverse effects of Aflatoxin B1 on D. melanogaster

“…Similar effects have also been observed in different animal groups, such as mice, rat and mouse (Bashandy et al, 1994;Nair and Verma, 2000;Verma and Nair, 2001). Besides, the extreme sensitivity of larvae and pupae and also their mortality in high concentrations (1.4 ppm) were one of the most important reasons for the decrease in the number of offspring (Kirk et al, 1971;Llwellyn and Chinnici, 1978).…”

“…For example, Lalor et al (1976) found that growth on AFB 1 media of D. melanogaster caused significant increases in egg-to-adult developmental time. Larval and pupal toxic effects caused by AFB 1 have also been demonstrated by various authors in Musca domestica (Beard and Walton, 1971) and D. melanogaster (Kirk et al, 1971). Besides, according Chinnici et al (1979), second and third larvae of strain A-9 showed significant mortality rates when grown at 0.88 ppm AFB 1 .…”

Selenium protective activity against aflatoxin B1 adverse affects on Drosophila melanogaster

“…For example, Lalor et al, (1976) found that growth on AFB 1 media of D.melanogaster caused significant increases in egg-to-adult developmental time. Larval and pupal toxic effects caused by AFB 1 have also been demonstrated by various authors in Musca domestica (Beard and Walton, 1971) and D.melanogaster (Kirk et al, 1971). Besides, according to Chinnici et al,(1979), second and third larvae of strain A-9 showed significant mortality rates when grown at 0.88 ppm AFB 1 .…”

“…Similar effects have also been observed in different animal groups such as mice, rat and mouse (Bashandy et al, 1994;Nair and Verma, 2000;Verma and Nair, 2001). Besides, the extreme sensitivity of larvae and pupae and also their mortality in high concentrations (1.4 ppm) were one of the most important reasons of the decrease in the number of offsprings ( Kirk et al, 1971;Llwellyn and Chinnici, 1978). Furthermore, when F 1 individuals were examined as phenotypic, malformed individuals were also observed and malformation was concentrated mainly on wing, leg and thorax and neither the formation of extremities nor their lackness have been found.…”

A systematic literature review on the effects of mycotoxin exposure on insects and on mycotoxin accumulation and biotransformation

“…Exposure to 800 µg/kg AFB 1 resulted in 11% malformation as opposed to 7% for larvae exposed to 200 µg/kg AFB 1 (Şişman 2006 ). Furthermore, feeding D. melanogaster (strain Oregon R) with 10,000 µg/kg AFB 1 resulted in a doubling of larval and pupal development time (Kirk et al 1971 ). Additionally, it has been shown that effects caused by mycotoxin exposure of D. melanogaster on growth can vary between both strains and larval stages.…”