Effect of a tunnel‐structured β‐tricalcium phosphate graft material on periodontal regeneration: a pilot study in a canine one‐wall intrabony defect model

Abstract

Tunnel β-TCP serves as a scaffold for new bone formation in one-wall intrabony defects.

Ridge Preservation After Tooth Extraction With Buccal Bone Plate Deficiency Using Tunnel Structured β‐Tricalcium Phosphate Blocks: A 2‐Month Histologic Pilot Study in Beagle Dogs

“…This material was easy to trim and fit to bone defects of any size because of the weak connectivity between the tunnel β‐TCP particles. In addition, the tubular structure of this material may promote angiogenesis and early stability through capillarity 39 , 46 . Commonly, alveolar ridge‐preservation techniques use bone grafts with membranes to maintain the space and allow osteogenic cells to exclusively populate the defect 47 .…”

“…The preparation of tunnel β‐TCP blocks was performed as described previously 38 , 39 . In brief, β‐TCP slurry was prepared by mixing a paste of TCP, polyvinyl alcohol, and distilled water at a molar ratio of 8:2:10.…”

“…In a rabbit model, significantly higher vascularization was observed in graft materials with a pore size of 300 μm than those with smaller pore diameters 37 . Based on this concept, tunnel‐shaped β‐TCP, with an inner diameter of 300 μm, an outer diameter of 500 μm, and a length of 1 mm, was fabricated 38 , 39 . A block‐type graft material was manufactured by randomly aggregating these particles 38 , 39 .…”

Evaluation of Bone Regeneration by porous Alpha-Tricalcium Phosphate/Atelocollagen Sponge Composite in Critical-Sized Rat Calvarial Defects

“…Restoration of lost alveolar bone remains as one of the main objectives of periodontal surgery 1,2) . Among the various types of bone grafts available for grafting procedures, autogenous bone grafts are considered to be the gold standard in alveolar defect reconstruction 3) .…”

Calcium Orthophosphates (CaPo ) and Dentistry

“…In an acidic oral environment, such biocomposites take advantages of the ability of ACPs to release calcium and orthophosphate ions, which potentially can take part in enamel remineralization [ α-TCP and β-TCP: According to the available literature, α-TCP and/or β-TCP (unfortunately, the authors of the publications on the subject not always specify which of them was used) are widely used in dentistry and dentistry-related fields. For example, they are used for augmentation of the surrounding bones [171, [282][283][284][285][286][287][288][289], in maxillofacial surgery [290][291][292][293], as a component of root canal sealers [294], as implant coatings [295], as remineralization [296][297][298][299] and pulpotomy [300] agents, for dental pulp capping [301][302][303][304][305][306], to treat perforations [307,308], as endodontic plugs [309] and to fill various types of bone defects and lesions [310][311][312][313][314][315][316][317][318].…”