Efeito da utilização de plasma rico em plaquetas na osteointegração dos enxertos ósseos homólogos criopreservados: estudo histomorfométrico em coelhos

Augusto, Luiz; Santos, Ubirajara

doi:10.11606/d.5.2007.tde-16082007-160750

Cited by 3 publications

(3 citation statements)

References 99 publications

(125 reference statements)

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“…At the end of 15 days was found graft integration in receptor bed, so the pressure of the sponges and angiogenesis stimulating factors present in the PRP are capable to replacing the granulation tissue and promote proper healing of the grafts. The results of this trial are consistent with Vendramin et al (2010b), who used the platelet rich plasma autologous skin grafts in rabbits, and there were favorable results in wound healing. Regarding the use of surgical sponges, the results obtained in this study corroborate Zanini et al (2004), who used a surgical sponge as a pressure dressing for skin grafts in humans, and obtained favorable results in respect of healing, and indicate and advise the use of surgical sponges in skin grafts.…”

Section: Resultssupporting

confidence: 86%

“…However, the successful healing of the grafts depends on proper angiogenesis (Pazzini et al, 2015). Thus, the problems encountered related to neovascularization in surgical procedures are the subject of many studies, and the platelet-rich plasma (PRP) is a substance that has been researched to have factors that stimulate angiogenesis and aid in tissue repair (Santos, 2007). Studies indicate that this product can stimulate various processes involved in tissue recovery mainly epithelialization and angiogenesis (Pazzini et al, 2016a).…”

Section: Introductionmentioning

confidence: 99%

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Surgical sponge associated with platelets rich plasma in skin mesh grafts and layer in rabbits (Oryctolagus cuniculus)

Pazzini

Serafim²,

Uscátegui

et al. 2018

Arq. Bras. Med. Vet. Zootec.

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The aim of this study was to evaluate of the efficacy of PRP employment associated with surgical sponges to improve the integration of the graft in the recipient bed. It was held at the Veterinary Hospital UNESP, Campus of Jaboticabal - SP, a study of 64 rabbits, divided into eight groups with eight animals. The groups were divided in control with saline solution 0,9%, control with PRP both without the sponge, surgical sponge with PRP, surgical sponge without PRP, and were used mesh and layer grafts in the respective groups. The data were submitted to statistical analysis (paired t-test, Kruskal-Wallis test, with subsequent use of the multiple comparison tests of Dunn, analysis of variance (F) test, Tukey test, P< 0.05). Edema and exudate with 3 and 3 and 7 days (P= 0,03 e P= 0,0049); coloring on the 14th day (P= 0,0001); cosmetic appearance on the 7th and 14th day (P= 0,0026 and P= 0,0001); mononuclear cells (P= 0,01) and polymorphonuclear (P= 0,01); fibroblast proliferation (P= 0,01); collagenous (P= 0,05); hemorrhage (P-007); necrosis and re-epithelialization (P= 0,2928 and P= 0,1). We concluded that the use of Platelet Rich Plasma Gel on skin grafts associated with a sponge as a compressive dressing promote the skin graft survival without a previous granulation tissue.

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Section: Resultssupporting

confidence: 86%

Section: Introductionmentioning

confidence: 99%

Surgical sponge associated with platelets rich plasma in skin mesh grafts and layer in rabbits (Oryctolagus cuniculus)

Pazzini

Serafim²,

Uscátegui

et al. 2018

Arq. Bras. Med. Vet. Zootec.

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“…However, in the platelet studies are the subject of most interest, because they are easy to obtain and incorporate other essential substances in the regeneration process and tissue repair (Santos, 2007). (Albuquerque et al, 2008) Platelet concentrate can also be applied directly on the wound or incision, without being in the form of gel (Jameson, 2007).…”

Section: Platelet-rich Plasma (Prp)mentioning

confidence: 99%

Skin Grafts Associated with Platelet Rich Plasma and Surgical Sponge - Literature Review

Pazzini¹,

Serafim²,

Uscátegui³

et al. 2017

JAS

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Skin graft is one of the techniques used to reconstruct surgical wounds. The graft is composed of epidermal and dermal segments that are completely removed from the donor region and transferred to the recipient bed. After its implantation it's recommended to make compressive dressing in the receiver bed. Since the grafts do not have a vascular pedicle, it's important to make the compressive dressing to improve graft contact with the wound and allow adequate angiogenesis. The compressive dressing is made with a sponge or foam, which offers adequate protection and reduces the discomfort of the patient in the postoperative period. The use of platelet-rich plasma (PRP) is the objective of several studies associated with the reduction of postoperative surgical complications, especially necrosis. This product is a result of the centrifugation of the patient's blood that promotes the separation of its constituents and allows the extraction of plasma with higher concentration of platelets. PRP improves the tissue healing process by releasing biological mediators and growth factors at the site of application. Researches on platelet-rich plasma used in reconstructive surgery are important because this product has therapeutic characteristics to promote healing. When it's used in skin grafts, platelet-rich plasma is able to improve graft integration in the recipient bed, and reduce necrosis after the surgical procedure. The use of postoperative surgical sponges associated with platelet-rich plasma is indicated to improve the healing of the graft and to avoid its displacement of the recipient bed.

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Cryopreserved Musculoskeletal Tissue Bank in Dentistry: State of the Art and Perspectives

Santos¹,

Croci²,

Armentano³

et al. 2012

Current Frontiers in Cryopreservation

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Efeito da utilização de plasma rico em plaquetas na osteointegração dos enxertos ósseos homólogos criopreservados: estudo histomorfométrico em coelhos

Cited by 3 publications

References 99 publications

Surgical sponge associated with platelets rich plasma in skin mesh grafts and layer in rabbits (Oryctolagus cuniculus)

Surgical sponge associated with platelets rich plasma in skin mesh grafts and layer in rabbits (Oryctolagus cuniculus)

Skin Grafts Associated with Platelet Rich Plasma and Surgical Sponge - Literature Review

Cryopreserved Musculoskeletal Tissue Bank in Dentistry: State of the Art and Perspectives

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