Efecto del tabaquismo sobre la espermatogénesis en hombres con infertilidad idiopática

Abstract

The results show that tobacco alters sperm concentration and morphology with an increase of immature forms, demonstrating an altered spermatogenesis process. The consumption of tobacco should be evaluated to carry out the integral study of infertile man.

Nicotine Effects and Receptor Expression on Human Spermatozoa: Possible Neuroendocrine Mechanism

“…In humans, it has been shown that cigarette smoke is able to alter sperm density, motility, morphology and seminal fluid leukocyte concentration. Effects of the cigarette smoke on sperm DNA integrity, aneuploidy rate, production of free oxygen radicals (ROS) have been evaluated, but the results of these studies appear conflicting: some have shown a negative effect (Stillman et al, 1986; Close et al, 1990; Pacifici et al, 1993; Sofikitis et al, 1995; Vine et al, 1996; Curtis et al, 1997; Rubes et al, 1998; Zhang et al, 2000; Saleh et al, 2002; Kunzle et al, 2003; Said et al, 2005; Sepaniak et al, 2006; Gaur et al, 2007; Reina Bouvet et al, 2007; Calogero et al, 2009; Chohan and Badawy, 2010; El-Melegy and Ali, 2011), while others reported no effect (Vogt et al, 1986; Dikshit et al, 1987; Oldereid et al, 1989; Lewin et al, 1991; Belcheva et al, 2004). …”