The study aims to analyze the related publications on open innovation and entrepreneurship on the Web of Science in the period from 2011 to 2020. The study methodology was bibliometrics and researched on the themes open innovation and entrepreneurship analyzing the following aspects: main authors, analysis by year, main institutions, funding agencies, keywords, main newspapers, main countries and languages, areas of knowledge, and the relationship between authors with the most publications and the most cited. In addition, the authors sought to analyze the co-citation of the aspects listed above. The results of the study, through CiteSpace, encompass multiplicity and diversity as to the authors who most published on the topic, and they found the institution that stood out the most in terms of publications.