Eczema Herpeticum: Clinical and Pathophysiological Aspects

Damour, Alexia; Garcia, Magali; Sénéschal, Julien; Lévêque, Nicolas; Bodet, Charles

doi:10.1007/s12016-019-08768-3

Cited by 60 publications

(67 citation statements)

References 130 publications

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“…[114] The skin of AD individuals are highly predisposed to colonization or infection by various organisms most especially Staphylococcus aureus and Herpes simplex virus. [115] The microbial organisms produce superantigens which stimulates marked inflammation. S. aureus has been implicated as a trigger of AD and as a factor responsible for chronic relapsing clinical course.…”

Section: Triggers For Ad Onset and Exacerbationmentioning

confidence: 99%

“…aureus while their neutralization significantly leads to clearance of the infective agent. [115][116][117] Apart from areas of infection, S aureus also colonizes normal-appearing skin in AD patients. [117] Viral skin infections occur in AD patients more than other individuals without atopy.…”

Section: Triggers For Ad Onset and Exacerbationmentioning

confidence: 99%

“…According to Damour et al, susceptibility is increased by overexpression of Th2 cytokines -IL-4, IL-13, IL-25, IL-33, and TSLP, low the AMP cathelicidin LL-37 and HBD-2 production; reduced IFN-γ, defect in cellular immune response by NK cells and dendritic cells. [115] HSV may present as umbilicated vesicles, punched out erosions, impetigo-like lesions or secondarily infect atopic skin lesions. [115] Tzanck smear, PCR and viral culture can be used to confirm diagnosis.…”

Section: Triggers For Ad Onset and Exacerbationmentioning

confidence: 99%

“…[115] HSV may present as umbilicated vesicles, punched out erosions, impetigo-like lesions or secondarily infect atopic skin lesions. [115] Tzanck smear, PCR and viral culture can be used to confirm diagnosis. Also, fungi infection particularly Malassezia sympodialis has been found to contribute to chronic inflammation in AD, and it is associated with specific IgE antibodies against M. sympodialis.…”

Section: Triggers For Ad Onset and Exacerbationmentioning

confidence: 99%

See 3 more Smart Citations

Atopic Dermatitis in Adults: Epidemiology, Risk Factors, Pathogenesis, Clinical Features, and Management

Oninla¹,

Akinkugbe²,

Otike-Odibi³

et al. 2021

Atopic Dermatitis - Essential Issues

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Atopic dermatitis (AD) is an itchy chronic relapsing inflammatory skin condition mostly affecting children than adults. Eczematous conditions are common worldwide with increase in the prevalence in both developed and developing countries. AD in adults is of two types – the first type starts as AD in childhood and gradually progresses to adulthood (Persistent AD) and the second type results from AD developing in adulthood (Adult-onset AD). The article reviews and discusses this condition in adults considering the epidemiology, risk factors, pathogenesis, diagnostic criteria, and management of this condition.

show abstract

Section: Triggers For Ad Onset and Exacerbationmentioning

confidence: 99%

Section: Triggers For Ad Onset and Exacerbationmentioning

confidence: 99%

Section: Triggers For Ad Onset and Exacerbationmentioning

confidence: 99%

Section: Triggers For Ad Onset and Exacerbationmentioning

confidence: 99%

See 2 more Smart Citations

Atopic Dermatitis in Adults: Epidemiology, Risk Factors, Pathogenesis, Clinical Features, and Management

Oninla¹,

Akinkugbe²,

Otike-Odibi³

et al. 2021

Atopic Dermatitis - Essential Issues

View full text Add to dashboard Cite

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“…Kaposi‐Juliusberg Varicelliform Eruption (KVE), also called eczema herpeticum, is a disseminated skin infection, attributable to a virus usually causing localized vesicular eruptions, arising in a patient with an underlying cutaneous disease, mainly atopic dermatitis. 1 More rarely, KVE may occur as a complication of Darier disease (DD). 2 We report a case of KVE complicating DD, with a possible immunosuppressive role played by cannabinoid abuse.…”

mentioning

confidence: 99%

Kaposi‐Juliusberg Varicelliform Eruption complicating Darier disease: May cannabinoid abuse be an underestimated risk factor?

Russo

Labate

Cozzani

et al. 2021

Clinical Case Reports

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Viral Infections

Harwood,

Sterling

2024

Rook's Textbook of Dermatology

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Viruses can cause disease in the skin or mucosa by direct infection or, via a systemic infection, produce secondary skin abnormalities. The chapter reviews the viruses associated with skin lesions, outlining the pathophysiology, the clinical features, diagnostic methods and the approaches to treatment. Primary skin infection following direct contact occurs with poxviruses, some herpesviruses and papillomaviruses leading to visible features which may be readily diagnostic. Less specific skin changes are seen with systemic infections, when infection is often via mucosae or inoculation, for example with parvovirus, measles or coronavirus and for these infections, diagnosis will usually involve body fluid analysis.

show abstract

Eczema Herpeticum: Clinical and Pathophysiological Aspects

Cited by 60 publications

References 130 publications

Atopic Dermatitis in Adults: Epidemiology, Risk Factors, Pathogenesis, Clinical Features, and Management

Atopic Dermatitis in Adults: Epidemiology, Risk Factors, Pathogenesis, Clinical Features, and Management

Kaposi‐Juliusberg Varicelliform Eruption complicating Darier disease: May cannabinoid abuse be an underestimated risk factor?

Viral Infections

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