Atopic Dermatitis in Adults: Epidemiology, Risk Factors, Pathogenesis, Clinical Features, and Management

Oninla, Olumayowa Abimbola; Akinkugbe, Ayesha; Otike-Odibi, Bolaji; Oripelaye, Mufutau Muphy; Olanrewaju, Fatai Olatunde

doi:10.5772/intechopen.97287

Cited by 3 publications

(3 citation statements)

References 148 publications

(159 reference statements)

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“…This skin condition is more prevalent in children than adults. 14 Symptoms of AD may appear for the first time at any age, but generally symptoms appear before the age of 5 years old, with the highest prevalence between the ages of 3 and 6 months old. 15 The findings of this study indicate a higher incidence of AD patients in the childhood phase compared to the adult phase.…”

Section: Discussionmentioning

confidence: 99%

“…This finding aligns with existing research indicating a significant relationship between IgE-mediated food allergies and the severity of AD in adults. 14 AD is associated with other allergic conditions and serves as an early manifestation of atopic march. The majority of AD patients usually exhibit a personal and/or family history of atopy, including bronchial asthma and allergic rhinitis.…”

Section: Discussionmentioning

confidence: 99%

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Profile of Atopic Dermatitis at Dermatovenereology Outpatient Clinic at Tertiary Hospital in Surabaya, Indonesia

Damayanti,

Brahmana,

Qurnianingsih

et al. 2024

BIKK

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Background: Atopic dermatitis (AD) is a pruritic skin condition with erythema, lichenified patches, and excoriations from scratching the skin and often affect the patient's quality of life. Patient history and clinical manifestations are key elements in various diagnostic criteria. Therefore, it is important to know clinical profile of AD patients. Purpose: To describe profile of patients with AD at Dermatovenereology Outpatient Clinic Dr. Soetomo General Academic Hospital Surabaya in 2019-2021. Methods: This study is a retrospective descriptive study using secondary data from the patients' medical records at Dermatovenereology Outpatient Clinic Dr. Soetomo General Academic Hospital Surabaya in 2019-2021. Result: New AD patients in total were 89 patients, dominated by female (53.9%) in age group 2-12 years (37.1%). The most common complaint was itching (83.1%) and trigger factor was unknown (43.8%). Most patients had previous history of atopy (52.8%) and did not know about their family history of atopy (37%). The most common lesion efflorescence was erythematous macule (59.6%) and located on inferior extremity (43.8%). The most frequent systemic therapy was Cetirizine (71.9%) and topical therapy was hypoallergenic emollient (42.7%). Conclusion: Most of AD patients are female in the 2-12 year age group, come with the complaint of itching and do not know the trigger factor, they mostly had previous history of atopy, but they mostly do not know about their family history of atopy, the most common lesion efflorescence are erythematous macules and the location on inferior extremity with the most given therapy are Cetirizine and hypoallergenic emollient.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Profile of Atopic Dermatitis at Dermatovenereology Outpatient Clinic at Tertiary Hospital in Surabaya, Indonesia

Damayanti,

Brahmana,

Qurnianingsih

et al. 2024

BIKK

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“…Individu dengan Dermatitis atopik dalam tingkat sedang hingga berat juga dapat menunjukkan hiperpigmentasi retikulat yang didapat pada leher (juga disebut 'leher kotor') yang dihasilkan dari kombinasi hiperpigmentasi pasca inflamasi dan gesekan. Pruritus atau sensasi tidak menyenangkan pada kulit yang memicu rasa gatal sering menyebabkan trauma kulit, ketidaknyamanan, dan gangguan tidur (Oninla et al, 2021), yang pada akhirnya berdampak negatif pada kualitas hidup pasien dan keluarga. Dalam kebanyakan kasus, Dermatitis atopik berkembang selama masa kanak-kanak (Kaufman et al, 2018).…”

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Prebiotik dan Dermatitis Atopik pada Anak

Fauziyyah¹,

Ikhssani

2022

nutrient

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Dermatitis atopik adalah kondisi kulit berupa inflamasi kronis yang umum ditandai dengan gatal berulang yang parah. Gejala yang muncul termasuk kulit kering, lesi eksim, eritema (kemerahan), edema, erosi, oozing dan pengerasan kulit, yang bervariasi menurut kronisitas lesi dan usia pasien yang terkena Dermatitis atopik. Individu dengan Dermatitis atopik dalam tingkat sedang hingga berat juga dapat menunjukkan hiperpigmentasi retikulat yang didapat pada leher (juga disebut 'leher kotor') yang dihasilkan dari kombinasi hiperpigmentasi pasca inflamasi dan gesekan. Pruritus atau sensasi tidak menyenangkan pada kulit yang memicu rasa gatal sering menyebabkan trauma kulit, ketidaknyamanan, dan gangguan tidur. Memperbaiki status gizi, pencernaan nutrisi, respon imun spesifik dan non spesifik, efek menguntungkan pada saluran pencernaan dan kulit, adalah upaya untuk mendukung penggunaan pra dan probiotik pada pasien dengan Dermatitis Atopik. Namun, tidak ada cukup data dalam literatur untuk menjawab pertanyaan mengenai dosis optimal, waktu optimal untuk memulai pengobatan dan durasi yang diperlukan untuk menunjukkan efek yang menguntungkan; penggunaan probiotik yang dipersonalisasi menurut dysbiosis kolon dapat dikaitkan dengan hasil terbaik. Tinjauan pustaka ini mengkaji Prebiotik dan Dermatitis Atopik pada Anak.

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Skin Dysbiosis in Atopic Dogs: Is Phage Therapy an Alternative to Antibiotics?

Šumonja,

Kotnik

2024

SVR

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Bacterial overgrowth, also known as dysbiosis, is a common concomitant of canine atopic dermatitis. Microbial diversity is decreased and coagulase-positive staphylococci are more abundant in dogs with canine atopic dermatitis compared to healthy dogs. Antimicrobial therapy restores the diversity of the skin microbiome; however, this effect can diminish after treatment is discontinued. Therapies for skin dysbiosis have traditionally included antibiotics and antiseptic medications. Due to increasing microbial resistance to antibiotics, the era of novel antimicrobial agents for the treatment of skin infections has already begun. Recent research highlights potential new treatment options, of which one of the most promising appears to be the use of bacteriophages. Bacteriophages are viruses that can infect and kill bacteria without having negative effects on human or animal cells. This article provides an update on human and veterinary research on phage therapy as a potential approach for the treatment of bacterial infections, with a focus on the treatment of skin dysbiosis in atopic dogs. The clear clinical potential of phage therapy, its advantages and disadvantages, and the legal, biological, technical, and economic challenges it faces for its further implementation and wider application are outlined.

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Atopic Dermatitis in Adults: Epidemiology, Risk Factors, Pathogenesis, Clinical Features, and Management

Cited by 3 publications

References 148 publications

Profile of Atopic Dermatitis at Dermatovenereology Outpatient Clinic at Tertiary Hospital in Surabaya, Indonesia

Profile of Atopic Dermatitis at Dermatovenereology Outpatient Clinic at Tertiary Hospital in Surabaya, Indonesia

Prebiotik dan Dermatitis Atopik pada Anak

Skin Dysbiosis in Atopic Dogs: Is Phage Therapy an Alternative to Antibiotics?

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