Kaposi‐Juliusberg Varicelliform Eruption complicating Darier disease: May cannabinoid abuse be an underestimated risk factor?

Abstract

Cannabinoid abuse may facilitate disseminated skin infection by herpes viruses in predisposed patients. These patients should be counselled about that.

Cutaneous Squamous Cell Carcinoma and Lichen Simplex Chronicus Successfully Treated with Topical Cannabinoid Oil: A Case Report and Summary of Cannabinoids in Dermatology

“…Topical cannabinoids can be associated with cutaneous adverse events, such as allergic contact dermatitis and contact urticaria (Table 8) [10][11][12][13][14][15][16]. A study of dispensaries in Los Angeles, California, discovered that 84% of over-the-counter topical cannabinoids had one or more North American contact dermatitis group (NACDG) allergens [17].…”

“…Patch testing yielded a positive result for cannabis leaf [14] Eczema herpeticum Cannabinoid abuse may be an underestimated risk factor for triggering eczema herpeticum in patients with atopic dermatitis or Darier disease. Eczema herpeticum is caused by the reactivation of the latent herpes simplex virus [15] Erythema ab igne Erythema ab igne is triggered by excessive heat exposure from heating devices, heating pads, or laptop use. It can also be seen as a complication of cannabis hyperemesis syndrome [16] TABLE 8: Cannabinoids and adverse cutaneous events CBD, cannabidiol.…”

“…A 22-year-old man with a history of cannabis abuse and Darier disease subsequently developed eczema herpeticum, which presented as a disseminated mucocutaneous eruption involving the oral mucosa, face, trunk, and groin. His viral infection gradually improved after receiving intravenous acyclovir (at a dose of 5 mg/kg three times a day) and parenteral nutrition [15].…”