Easy-to-execute 'One-pot' Synthesis of 1,2,4,5-Tetrazines Catalyzed by Activated Fly Ash

Abstract

요 약. Thiourea/urea, 다양한 aromatic aldehydes, ammonium acetate의 세가지 요소를 가지고 마이크로파의 조 사하에서 무수조건의 활성화된 비산화재를 촉매로 사용하여 높은 수율의 6-aryl-1,2,4,5-tetrazinan-3-thiones/ones를 얻었 다. 6-aryl-1,2,4,5-tetrazinan-3-thiones/ones의 구조는 녹는점, MS, IR,주제어: 활성화된 비산회, 6-aryl-1,2,4,5-tetrazinan-3-thiones/ones, one-pot 합성, 다성분 반응, 무수조건 ABSTRACT. Three-component coupling of thiourea/urea, various structurally diverse aromatic aldehydes and ammonium acetate is catalyzed by activated fly ash in dry media under microwave irradiation to give 6-aryl-1,2,4,5-tetrazinan-3-thiones/ones in good yields. The structure of 6-aryl-1,2,4,5-tetrazinan-3-thiones/ones have been elucidated on the basis of their melting points, elemental analysis, MS, IR, C NMR and two dimensional NMR spectral studies including Homonuclear Correlation (HOMOCOR) and Heteronuclear Single Quantum Correlation (HSQC) spectra.

Synthesis, spectral studies and insect antifeedant activities of some 4-substituted 1-naphthacyl bromide and its esters

“…Many solvent-assisted brominating methods for the bromination of alkyl and aryl compounds by direct use of bromine solution in alkaline or acid medium have been reported in the literature [3,[41][42][43]. In the present work, the author has attempted to brominate naphthyl keto compounds with an alternative reagent like Winkler's solution (bromate-bromide solution) in the presence of aqueous phase catalyst fly-ash.…”

“…In the present work, the author has attempted to brominate naphthyl keto compounds with an alternative reagent like Winkler's solution (bromate-bromide solution) in the presence of aqueous phase catalyst fly-ash. The bromate-bromide solution was harmless to the reaction [3,[41][42][43] as well as the environment. Various 1-naphthyl ketones containing electron withdrawing and electron donating groups in position 4 have been subjected to bromination at acyl methyl group with Winkler's solution in the presence of fly-ash catalyst under water medium (Scheme 1).…”

Fly-ash:H2O Assisted Aldol Condensation: Effect of Solvents on the Synthesis of Some Aryl (E) 2-propen-1-ones

“…The waste and harmful air pollutant fly-ash containing many chemical species such as [12,[21][22][23][24] Si02, Fe203, AI2O3, CaO, MgO and insoluble residues. This pollutant is used as useful catalyst for organic synthesis.…”

One-pot synthesis and in vitro microbiological evaluation of pyrimidinyl thiazolidinones catalyzed by activated fly ash in dry media

“…Recently microwave-assisted activated fly-ash catalyzed Knoevenagel condensation, synthesis of amides, Schiff bases formation, Biginelli and Hantzsch reactions have been reported [4]. In addition, activated fly ash is used for the "one-pot" synthesis of 1,2,4,5-tetrazines [5] and 1,2,3-selenadiazoles [6].…”