Early Pathological Changes of Photocoagulation in the Human Retina

Curtin, Victor T.; Norton, Edward W.D.

doi:10.1001/archopht.1963.00960040750012

Cited by 12 publications

(2 citation statements)

References 5 publications

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“…Many attempts have been made, therefore, to develop methods of conservative treatment for this type of malignant disease, whereby the tumour may be destroyed and some useful vision preserved in the treated eye. The methods adopted have included destruction of the neoplasm by diathermy (Weve, 1935;Goldsmith, 1943;Melchers, 1953;Boniuk and Girard, 1965;Davidorf et al, 1970); ionising radiation using radon seeds (Moore et al, 1931;Newman et al, 1970), radium discs (Stallard, 1952), cobalt-60 gamma-ray applicators (Stallard, 1959(Stallard, , 1968Bedford, 1968;Long et al, 1971), and ruthenium-106 beta-ray applicators (Lommatzsch, 1973); light coagulation (Meyer-Schwickerath, 1961;Lund, 1962Lund, , 1966Curtin and Norton, 1963;Makley et al, 1965;Hepler et al, 1968;Francois, 1965, 1968a andDufour et al, 1968;Vogel, 1972Vogel, , 1973, and cryotherapy (Lincoff et al, 1967;Campinchi, 1968;Davidorf et al, 1970). Others have attempted to save the eye by surgical techniques as by choroidectomy (Stallard, 1973).…”

Section: Discussionmentioning

confidence: 99%

Histopathological changes in malignant melanomas of the choroid after cobalt plaque therapy.

Macfaul¹,

Morgan²

1977

British Journal of Ophthalmology

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with malignant melanoma of the choroid of which 300 were treated by primary enucleation and 100 by the application of a cobalt plaque. Others were treated by light coagulation, and in some cases, particularly in older people, no active treatment was given but the patient was kept under careful observation.The purpose of this paper is to report 23 cases in which the eyes have been removed after cobalt plaque therapy for malignant melanoma of the choroid and to describe the histopathological changes. Case reportsThe ages of the patients varied between 30 and 75 years (average 51 years), and there were 14 males and 9 females. The interval between treatment by cobalt plaque therapy and enucleation of the affected eye varied from 7 months to 13 years and 10 months, but when the latter case is excluded the average interval was 32 months. The reasons for enucleation fell into 2 groups-failure of treatment with strong suspicion or clear clinical evidence of continued growth of the tumour, and radiation complications in the treated eye.

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Section: Discussionmentioning

confidence: 99%

Histopathological changes in malignant melanomas of the choroid after cobalt plaque therapy.

Macfaul¹,

Morgan²

1977

British Journal of Ophthalmology

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“…These phenomena are well documented in the literature. [1][2][3][4][5][6][7] In view of the recent interest in the use of cryopexy for the treatment of retinal detachment, the present investigation was undertaken to assess the histologic effect on the vitreous of subfreezing temperatures applied to the sclera. The changes were compared with those which occur with minimally applied Mira diathermy and Zeiss photocoagulation.…”

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confidence: 99%