Effect of Cryopexy on the Vitreous

Effects of Biological Stimuli on the Viscosity of the Vitreous

“…On the contrary, freezing of the excised human vitreous and cryoretinopexy of the rabbit eye caused less change of vitreous viscosity. Some investigators have studied this problem (Irvine et al 1957;Kirkconnel et al 1965). The present study provides evidence that the heat induced in the retina by diathermy may cause severe damage of the vitreous and suggests that cryopexy is safer than diathermy from the point of view of viscosity changes in the vitreous.…”

Globe perforation during strabismus surgery in an animal model: Treatment versus observation

“…29 In 2 studies, light cryopexy had no effect on the vitreous, but heavy cryopexy led to vitreous strand formation, macular pucker, exudative retinal detachment, and cystoid macular edema. 30,31 Diode laser retinal photocoagulation limits damage to outer retinal layers near the retinal pigment epithelium while being relatively sparing to inner retinal layers; the vitreous is not involved, thereby decreasing the likelihood of an inflammatory vitreoretinal reaction. 32,33 This study demonstrated a low incidence of anterior or posterior segment complications following globe perforation in rabbit eyes.…”

The Vitreous

“…Kirkconnel and Rubin (1965) studied this phenomenon and found that heavy cryopexy induced vitreous "strand" formation. Jaffe (1969) observed that freezing causes expansion of vitreous as water freezes and contraction as the water thaws.…”