“…Indeed, a diet low in all EAA (but adequate in all non-essential amino acids) was able to reproduce the effects of a protein-deficient diet on body weight, food intake, and energy expenditure [ 2 , 6 , 8 ]. A diet deficient in only one EAA has been shown to alter growth [ 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 ], increase or decrease food intake [ 6 , 9 , 10 , 11 , 12 , 13 , 15 , 16 , 18 , 21 ], modify body composition [ 9 , 10 , 12 , 13 , 15 , 16 , 17 , 18 , 21 , 22 ], and change or not energy expenditure [ 6 , 18 , 22 ]. However, the implication of one or several specific amino acids (AA) during protein deficiency was mainly investigated with a restricted number of EAA and few levels of deficiency.…”