Dysmaturity

Sjöstedt, Sven; Engleson, Gunnar; Rooth, Gösta

doi:10.1136/adc.33.168.123

Cited by 97 publications

(29 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The same explanation may account for the observation of Cook, Brodie and Allen (1957) that the mean cord blood Hb level of infants born with evidence of pre-natal hypoxia (meconium staining of nails, skin and cord) was 19-2 g./100 ml., significantly higher than the level of 17 g. in normal infants, and attributed by these authors to haemoconcentration. A similar conclusion was reached by Sjostedt, Engelson and Rooth (1958) who found that infants showing meconium staining of the skin tended to have an abnormally low oxygen saturation of umbilical vein blood, and an abnormally high mean Hb level, 17-0 g. against the normal 16-1.…”

Section: Archives Of Disease In Childhoodsupporting

confidence: 70%

The Fluid Shift from the Vascular Compartment Immediately after Birth

Gairdner¹,

Marks²,

Roscoe³

et al. 1958

Archives of Disease in Childhood

View full text Add to dashboard Cite

In an earlier paper (Gairdner, Marks and Roscoe, 1952) we drew attention to the fact that the haemoglobin (Hb) level during the first day of life is generally much higher than at birth. We questioned the adequacy of the current explanation, that any rise in the Hb level after birth is the result of transfer of placental blood, and suggested that the effect merited study. We now present further observations comparing the composition of cord blood at birth with venous blood taken from a few minutes to a few hours after birth. Hb, packed cell volume, (PCV), plasma protein and plasma sodium have been measured. From these comparisons we conclude that after birth there is usually a shift of fluid, mainly whole plasma, from the circulation. The volume of the plasma shift may be large, amounting to an appreciable fraction of the initial plasma volume, and the effect may consequently prove to be of some clinical importance. MaterialNinety-two infants were studied, of whom 73 were delivered vaginally and 19 by caesarean section. The mother's permission for blood sampling was obtained. Most of the subjects were normal, but a few of the mothers had toxaemia or diabetes; the results in these were similar to those of the normals and have not been separately analysed. MethodsThe cord was always clamped as soon as conveniently possible, both in vaginal and caesarean deliveries. A blood sample was taken by puncture of the umbilical vein between placenta and clamp. Subsequent specimens were taken from an external jugular, internal jugular or femoral vein, or from the ductus venosus (i.e. the continuation of the umbilical vein). The ductus venosus was used particularly for samples within a few minutes of birth. We have found that the ductus venosus can often be catheterized conveniently by inserting a widebore trocar into the terminal part of the umbilical vein in the cord, and threading a polythene catheter through it.Samples were taken into heparinized tubes. Hb and PCV were estimated as described previously (Marks, Gairdner and Roscoe, 1955), Hb being estimated in duplicate in most cases. Plasma protein was estimated by the biuret method, using 0-2 ml. plasma. Plasma sodium was estimated by flame photometer. These four estimations required about 2 5 ml. of blood. Results(i) Change in Hb Level a Few Hours After Birth. In 92 infants samples were taken one to eight hours after birth and compared with cord blood. These included 19 caesarean deliveries, all but two of which were elective, and thus performed before the onset of labour. Results are shown in Fig. 1. Twenty-two cases showed a negligible change (less than ± 5 %) in Hb level after birth; in two cases there was a fall exceeding 5%, while the remaining 68 (74% of the sample) showed a rise exceeding 5 %. This rise amounted to 6-15% in 24 cases, to 16-25% in 23 cases, and to 26 % or over in 21 cases. In five cases the rise exceeded 40 %, the most extreme example being that of an infant born with an abnormally low haemoglobin level of 10i5 g./100 ml. which six hours after birt...

show abstract

Section: Archives Of Disease In Childhoodsupporting

confidence: 70%

The Fluid Shift from the Vascular Compartment Immediately after Birth

Gairdner¹,

Marks²,

Roscoe³

et al. 1958

Archives of Disease in Childhood

View full text Add to dashboard Cite

show abstract

“…The importance of these findings in assessing the importance of abnormal labour in perinatal deaths is obvious, as also is the relation to 'postmaturity', 'prematurity', or 'dysmaturity' (Sjostedt, Engleson, and Booth, 1958), and to placental insufficiency, but a discussion of this is not within the scope of this study. It is, however, our belief that a critical assessment of neonatal ribs may help greatly in sorting out some of the factors in these clinical syndromes.…”

Section: Discussionmentioning

confidence: 97%

The costochondral junction during later stages of intrauterine life, and abnormal growth patterns found in association with perinatal death.

Emery¹,

Kalpaktsoglou²

1967

Archives of Disease in Childhood

View full text Add to dashboard Cite

“…Certain infants are of low birth weight for their gestational age regardless of whether they are born prematurely, at term, or even post term. We call these infants by a variety of names [30,17,45,46,51], the most common being intrauterine growth retarded [52], small-for-dates [8], small for gestational age [3] and intrauterine malnourished [43]. These names however, are simply descriptive and in no way clarify the etiology of the growth failure.…”

mentioning

confidence: 99%

Review article

1974

Journal of Perinatal Medicine

View full text Add to dashboard Cite

Dysmaturity

Cited by 97 publications

References 31 publications

The Fluid Shift from the Vascular Compartment Immediately after Birth

The Fluid Shift from the Vascular Compartment Immediately after Birth

The costochondral junction during later stages of intrauterine life, and abnormal growth patterns found in association with perinatal death.

Review article

Contact Info

Product

Resources

About