Dyslipidemia prevalence, awareness, treatment, control, and risk factors in Chinese rural population: the Henan rural cohort study

Abstract

BackgroundThe prevalence of dyslipidemia continue to increase in recent decades in China, however, little is known about the recent prevalence, awareness, treatment, control, and potential risk factors of dyslipidemia in the rural areas of China.MethodsA total of 39,207 participants aged 18–79 years were recruited for the epidemiological research from the Henan Rural Cohort study. The age- and sex-adjusted means (95% confidence intervals, CI) of serum lipid levels or percentages of prevalence, awareness, treatment, and control overall and in various population subgroups were estimated and compared by multiple linear regression or logistic regression. The multivariable logistic regression model was used to explore the associations between the socio-demographic factors and the prevalence, awareness, treatment and control of dyslipidemia.ResultsThe age- and sex-adjusted mean levels (95%CI) of total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were 4.76(4.75–4.77), 1.68(1.67–1.69),1.33(1.32–1.33), and 2.87 (2.86–2.88) mmol/L, respectively. Overall, the age-standardized prevalence of dyslipidemia was 32.21% (42.85% in men vs. 26.16% in women) in Chinese rural adults, with 5.11, 16.00, 19.27, and 4.76% for high TC, high TG, low HDL-C and high LDL-C, respectively. The age-standardized awareness, treatment and control of dyslipidemia were 15.07, 7.23, and 3.25%, respectively, which were higher in women than men, and increased steeply with age (Ptrend < 0.05). The proportion of prevalence, awareness, treatment, control of dyslipidemia differed significantly among various subpopulations while the awareness, treatment, and control rates were universally low in all subgroups (< 54, 36, and 15%, respectively). Increasing age, men, unhealthy lifestyles, positive family history of dyslipidemia, abnormal weight, type 2 diabetes mellitus and hypertension were independent risk factors of dyslipidemia.ConclusionDyslipidemia was common with unacceptably low awareness, treatment and control rates in rural China. Therefore, effective strategies are necessary for improving the status of the prevention, diagnosis, treatment, control of dyslipidemia in Chinese rural residents.Trial registration ChiCTR-OOC-15006699

Awareness, treatment, control, and determinants of dyslipidemia among adults in China: results from the China National Stroke Screening and Prevention Project (CNSSPP)

“…28 However, many reverse results have been reported between older ages and dyslipidemia control. 7,22,29 Again, differing from our ndings, a positive association between aging and the control of chronic diseases such as hypertension has been reported. 30 Our results may support the nding that dyslipidemias such as raised TC control rates may differ depending on the participants and country, and rates may range from 18-100%.…”

“…30 Our results may support the nding that dyslipidemias such as raised TC control rates may differ depending on the participants and country, and rates may range from 18-100%. 31 Consistent with prior reports, 22,29 we showed that women were more likely than men to have dyslipidemia awareness, treatment and control. Similarly, two studies on the management of raised LDL-C indicated that women recorded higher likelihood of awareness, treatment and control.…”

Prevalence of dyslipidemia and associated risk factors among adults aged ≥ 35 years in northern China: a cross-sectional study

“…We identified several factors that were associated with dyslipidemia in our study population. Our results that smoking, obesity, central obesity, hypertension, and diabetes can elevate the risk of dyslipidemia has been confirmed in many previous studies [29,30] . We also found that current drinkers had a lower risk of dyslipidemia; a similar result was reported by Song [31] .…”

Association of serum testosterone with different classes of glucose metabolism and the mediation effect of obesity: The Henan Rural Cohort Study

“…The participants of this study were from Henan Rural Cohort study . After excluding participants who received sex steroids or other androgen‐related drugs, 925 individuals aged 18 to 79 with T2DM were selected.…”

“…Information on the general characteristics of participants' demography (age, gender, educational attainment, socioeconomic status, etc. ), lifestyles (smoking status, alcohol intake, physical activity), and family history of disease was obtained by well‐trained investigators through face‐to‐face interviews using a structured questionnaire as previously described . The education attainment was categorized into never attended school, primary school, and junior secondary and above.…”