Dynamic Aspects of Films Prepared by a Sequential Deposition of Species: Perspectives for Smart and Responsive Materials

Lavalle, Philippe; Voegel, Jean‐Claude; Vautier, Dominique; Senger, Bernard; Schaaf, Pierre; Ball, Vincent

doi:10.1002/adma.201003309

Cited by 217 publications

(187 citation statements)

References 398 publications

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“…It is powerful technique for the fabrication of polymer-based multilayer films with dimensions from nano to micro, adjusted composition, and tunable cellular response. [5][6][7][8][9][10][11] Control over cellular functions such as adhesion, differentiation, and proliferation, 12-15 along with reservoir properties for a variety of biomolecules such as proteins, growth factors, genes, and drugs 7, 16-20 makes these films an attractive platform for cell-based applications.Despite the evident biological potential to employ the multilayers to recapitulate ECM, 3 the options to tune multilayer biodegradability are mostly limited to multilayer chemical 13,[21][22] that can significantly change multilayer properties. There is also a lack in understanding the mechanism of biomolecule-multilayer interaction that obviously defines biomolecule presentation/release from multilayers to cells and, as a result, cellular response.…”

mentioning

confidence: 99%

Biodegradation-Resistant Multilayers Coated with Gold Nanoparticles. Toward a Tailor-made Artificial Extracellular Matrix

Prokopović

Vikulina

Sustr

et al. 2016

ACS Appl. Mater. Interfaces

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Abstract:Polymer multicomponent coatings such as multilayers mimic extracellular matrix (ECM) that attracts significant attention for their use as functional supports for advanced cell culture and tissue engineering. Herein, biodegradation and molecular transport in hyaluronan/polylysine multilayers coated with gold nanoparticles was described. Nanoparticle 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 2 coating acts as semipermeable barrier that governs molecular transport into/from the multilayers and makes them biodegradation resistant. Model protein lysozyme (mimics of ECM soluble signals) diffuses in the multilayers as fast and slow diffusing populations existing in an equilibrium. Such composite system may have high potential to be exploited as degradationresistant drug delivery platforms suitable for cell-based applications.The extracellular matrix (ECM) provides not only a structural support for cellular growth, but also a biochemical milieu, which together define cell fate. 1 Artificial ECM is designed to mimic real ECM and to achieve cellular functions in laboratory designed materials similar as in nature.Artificial ECM consists of degradable supports made of natural or (semi)synthetic polymers which: i) recapitulate physical-chemical properties of real ECM, ii) host bioactive signaling molecules (e.g. hormones, cytokines, growth factors) to be presented to cells, and iii) possess tuned biodegradability. 2-3 The issues above are challenging for the fabrication of artificial ECM but are essential for successful applications in tissue engineering, diagnostics, and animal-free studies.Introduced in the early nineties, 4 layer-by-layer deposition proofed to be extremely useful in the field of bio-functional coatings. It is powerful technique for the fabrication of polymer-based multilayer films with dimensions from nano to micro, adjusted composition, and tunable cellular response. [5][6][7][8][9][10][11] Control over cellular functions such as adhesion, differentiation, and proliferation, 12-15 along with reservoir properties for a variety of biomolecules such as proteins, growth factors, genes, and drugs 7, 16-20 makes these films an attractive platform for cell-based applications.Despite the evident biological potential to employ the multilayers to recapitulate ECM, 3 the options to tune multilayer biodegradability are mostly limited to multilayer chemical 13,[21][22] that can significantly change multilayer properties. There is also a lack in understanding the mechanism of biomolecule-multilayer interaction that obviously defines biomolecule presentation/release from multilayers to cells and, as a result, cellular response. [23][24] In this work a new approach for the design of artificial ECM with controlled biodegradation based on the coating of multilayers with gold nanoparticles (GNPs) is present. The multilayers wer...

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mentioning

confidence: 99%

Biodegradation-Resistant Multilayers Coated with Gold Nanoparticles. Toward a Tailor-made Artificial Extracellular Matrix

Prokopović

Vikulina

Sustr

et al. 2016

ACS Appl. Mater. Interfaces

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“…This allows structures to be built into the third dimension and materials with true bulk properties to be prepared [ 59 ]. The wide variety of charged polymers, or indeed block copolymers, that are available with properties ranging from fluorescence to being redox active means that the origin of the functionality of such materials is not limited to the plasmonic NP inclusions [ 145 ]. This versatility allows precise designs with specific properties to be targeted.…”

Section: Referential Fabrication Techniquesmentioning

confidence: 99%

Self-assembled plasmonic metamaterials

et al. 2013

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Nowadays for the sake of convenience most plasmonic nanostructures are fabricated by top-down nanofabrication technologies. This offers great degrees of freedom to tailor the geometry with unprecedented precision. However, it often causes disadvantages as well. The structures available are usually planar and periodically arranged. Therefore, bulk plasmonic structures are difficult to fabricate and the periodic arrangement causes undesired effects, e.g., strong spatial dispersion is observed in metamaterials. These limitations can be mitigated by relying on bottom-up nanofabrication technologies. There, self-assembly methods and techniques from the field of colloidal nanochemistry are used to build complex functional unit cells in solution from an ensemble of simple building blocks, i.e., in most cases plasmonic nanoparticles. Achievable structures are characterized by a high degree of nominal order only on a shortrange scale. The precise spatial arrangement across larger dimensions is not possible in most cases; leading essentially to amorphous structures. Such self-assembled nanostructures require novel analytical means to describe their properties, innovative designs of functional elements that possess a desired near-and far-field response, and entail genuine nanofabrication and characterization techniques. Eventually, novel applications have to be perceived that are adapted to the specifics of the self-assembled nanostructures. This review shall document recent progress in this field of research. Emphasis is put on bottom-up amorphous metamaterials. We document the state-of-the-art but also critically assess the problems that have to be overcome.

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“…It is not our aim to be exhaustive, but to provide a comprehensive overview of the "LBL" deposition research. Interested readers may find some specialized and exhaustive review articles [7,8].…”

Section: Isrn Materials Sciencementioning

confidence: 99%

Deposition Mechanisms in Layer-by-Layer or Step-by-Step Deposition Methods: From Elastic and Impermeable Films to Soft Membranes with Ion Exchange Properties

Michel¹,

Toniazzo²,

Ruch³

et al. 2012

ISRN Materials Science

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The modification of solid-liquid interfaces with polyelectrolyte multilayer films appears as a versatile tool to confer new functionalities to surfaces in environmentally friendly conditions. Indeed such films are deposited by alternate dipping of the substrates in aqueous solutions containing the interacting species or spraying these solutions on the surface of the substrate. Spin coating is more and more used to produce similar films. The aim of this short review article is to provide an unifying picture about the deposition mechanisms of polyelectrolyte multilayer films. Often those films are described as growing either in a linear or in a supralinear growth regime with the number of deposited "layer pairs". The growth regime of PEM films can be controlled by operational parameters like the temperature or the ionic strength of the used solutions. The control over the growth regime of the films as a function of the number of deposition steps allows to control their functional properties: either hard and impermeable films in the case of linear growth or soft and permeable films in the case of supralinear growth. Such different properties can be obtained with a given combination of interacting species by changing the operational parameters during the film deposition.

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Dynamic Aspects of Films Prepared by a Sequential Deposition of Species: Perspectives for Smart and Responsive Materials

Cited by 217 publications

References 398 publications

Biodegradation-Resistant Multilayers Coated with Gold Nanoparticles. Toward a Tailor-made Artificial Extracellular Matrix

Biodegradation-Resistant Multilayers Coated with Gold Nanoparticles. Toward a Tailor-made Artificial Extracellular Matrix

Self-assembled plasmonic metamaterials

Deposition Mechanisms in Layer-by-Layer or Step-by-Step Deposition Methods: From Elastic and Impermeable Films to Soft Membranes with Ion Exchange Properties

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