Duration of immunity in dogs after vaccination or naturally acquired infection

Coyne, Michael J.; Burr, JM; Yule, Terecita D.; Harding, Mark J.; Tresnan, Dina B.; McGavin, D.

doi:10.1136/vr.149.17.509

Cited by 50 publications

(52 citation statements)

References 23 publications

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“…As an antibody titer of 1:32–1:42 against CAdV‐1 was the most reliable previously reported value (10), borderline‐titer antibody was designated as 1:40, and ‘high’ was designated as ≥1:160.…”

Section: Number and Ratio Of Dogs (A) Exhibiting Equal To Or Greater mentioning

confidence: 88%

Booster effect of canine distemper, canine parvovirus infection and infectious canine hepatitis combination vaccine in domesticated adult dogs

Taguchi¹,

Namikawa

Maruo

et al. 2012

Microbiology and Immunology

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Domesticated adult dogs with antibody titer classified as below 'high' to one or more of canine distemper virus (CDV), canine parvovirus type-2 (CPV-2) and canine adenovirus type-1 (CAdV-1) were then given an additional inoculation, and the effectiveness of this booster evaluated 2 months later. Consequently, CDV and CAdV-1 antibody titer experienced a significant increase, but the same effect was not observed in the antibody titer of CPV-2. These findings suggest that with additional inoculation, a booster effect may be expected in increasing antibody titers for CDV and CAdV-1, but it is unlikely to give an increase in CPV-2 antibody titer.

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Section: Number and Ratio Of Dogs (A) Exhibiting Equal To Or Greater mentioning

confidence: 88%

Booster effect of canine distemper, canine parvovirus infection and infectious canine hepatitis combination vaccine in domesticated adult dogs

Taguchi¹,

Namikawa

Maruo

et al. 2012

Microbiology and Immunology

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“…Direct empirical estimates of transmission rates (b) have thus far been impossible to obtain, hence we estimated a range of b values from field seroprevalence data (table 1), assuming equilibrium at g/b susceptibles [40,41]. Lifelong immunity to HeV in P. poliocephalus and P. alecto was assumed on the basis of long-lived detectable antibodies in captive flying foxes ( [39]; H. Field 2005, unpublished data), and long-lived immunity induced by other paramyxoviruses [42][43][44]. The period over which maternal immunity wanes was estimated from field and captive serosurveys [21,39].…”

Section: Methodsmentioning

confidence: 99%

Urban habituation, ecological connectivity and epidemic dampening: the emergence of Hendra virus from flying foxes (Pteropusspp.)

Plowright

Foley

Field³

et al. 2011

Proc. R. Soc. B.

290

385

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Anthropogenic environmental change is often implicated in the emergence of new zoonoses from wildlife; however, there is little mechanistic understanding of these causal links. Here, we examine the transmission dynamics of an emerging zoonotic paramyxovirus, Hendra virus (HeV), in its endemic host, Australian Pteropus bats (fruit bats or flying foxes). HeV is a biosecurity level 4 (BSL-4) pathogen, with a high case-fatality rate in humans and horses. With models parametrized from field and laboratory data, we explore a set of probable contributory mechanisms that explain the spatial and temporal pattern of HeV emergence; including urban habituation and decreased migration-two widely observed changes in flying fox ecology that result from anthropogenic transformation of bat habitat in Australia. Urban habituation increases the number of flying foxes in contact with human and domestic animal populations, and our models suggest that, in addition, decreased bat migratory behaviour could lead to a decline in population immunity, giving rise to more intense outbreaks after local viral reintroduction. Ten of the 14 known HeV outbreaks occurred near urbanized or sedentary flying fox populations, supporting these predictions. We also demonstrate that by incorporating waning maternal immunity into our models, the peak modelled prevalence coincides with the peak annual spill-over hazard for HeV. These results provide the first detailed mechanistic framework for understanding the sporadic temporal pattern of HeV emergence, and of the urban/peri-urban distribution of HeV outbreaks in horses and people.

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“…3,7 In a study to determine whether dogs either remained seropositive or responded serologically to revaccination to 5 viral agents after extended periods since their last vaccinations, dogs with SN CDV titers of $1:32 and HI CPV titers of $1:80 were regarded as being protective. 5 In the present study a protective titer of $1:80 was chosen for both CPV and CDV.…”

mentioning

confidence: 99%

Application of a Dot Enzyme-Linked Immunosorbent Assay for Evaluation of the Immune Status to Canine Parvovirus and Distemper Virus in Adult Dogs before Revaccination

2006

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Abstract. A growing body of literature has been published indicating that the current practice of annual vaccination of dogs may not be beneficial and in some cases may even be harmful. A number of publications have proposed assessing the immune status of dogs before annual revaccination. In this study the usefulness of a commercially available dot-ELISA kit was evaluated to determine the duration IgG antibody titers to canine parvovirus (CPV) and canine distemper virus (CDV) in 158 dogs vaccinated at least one year ago. Overall, the percentage of dogs with protective antibody titers to both CPV and CDV was 84%. The percentage of dogs with borderline antibody titers was 11% for CPV and 10% for CDV. Four percent of the dogs had no detectable antibody to CPV and 6% had no antibody to CDV. The results reported here are in good agreement with other studies measuring IgG antibody levels. It is concluded that the kit offers veterinarians the opportunity of determining antibody titers and revaccinating only those pets whose antibody titers to specific diseases have waned.

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Duration of immunity in dogs after vaccination or naturally acquired infection

Cited by 50 publications

References 23 publications

Booster effect of canine distemper, canine parvovirus infection and infectious canine hepatitis combination vaccine in domesticated adult dogs

Booster effect of canine distemper, canine parvovirus infection and infectious canine hepatitis combination vaccine in domesticated adult dogs

Urban habituation, ecological connectivity and epidemic dampening: the emergence of Hendra virus from flying foxes (Pteropusspp.)

Application of a Dot Enzyme-Linked Immunosorbent Assay for Evaluation of the Immune Status to Canine Parvovirus and Distemper Virus in Adult Dogs before Revaccination

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