Drug Susceptibility of Escherichia coli from Domestic Fowl

Abstract

Resistance of E. coli to antibiotics is not only an obstacle for the control of this infection but also provides conditions for the transfer of drug resistance factors to other enterobacteria (1). The presence of drug resistant E. coli in the fowl slaughtered for meat is of public health significance (4). Because of the concentration of poultry population around Ludhiana E. coli infections among domestic fowl are on the increase and drug resistant strains are often isolated from E. coli infections. Material and MethodsA total of 202 E. coli strains were isolated from 183 diseased and 19 apparently healthy fowl. One hundred and twenty-eight of the E. coli were typed into 23 0 serogroups, 21 were untypable and 53 were rough. The susceptibility of each of the 202 strains was tested against ten antimicrobial agents using discs'. The drug susceptibility test was carried out as described by CRUICKSHANK et al. (2) with commercially available Mueller Hinton agar as test medium. The criteria of CRUICKSHANK et al.(2) based on the diameter of the zone of inhibition around a 6mm. disc was used to classify the cultures as "sensitive", "moderately sensitive" and "resistantP. Results and DiscussionThe results of the susceptibility tests of E. coli strains to various antimicrobial agents are given in Table 1. The majority of E. coli strains (95-100 per cent) from diseased and apparently healthy fowl were susceptible to chloramphenicol, nalidixic acid and neomycin and as such these are the drugs of choice for treatment of E . coli infections. Comparing the results of the susceptibility of E. coli from apparently healthy and diseased fowl it was '' Span Diagnostics, Surat and Assoc. Discs, Bombay.

The Prevalence of Extended-Spectrum Beta-Lactamase-Producing Multidrug-Resistant Escherichia Coli in Poultry Chickens and Variation According to Farming Practices in Punjab, India

“…However, research is urgently needed given the projected large-scale increase in poultry production and antimicrobial use in the poultry sector ( Brahmachari et al 2013 ; Van Boeckel et al 2015 ). Sarma et al ( 1981 ) isolated E. coli from healthy and diseased fowl in Ludhiana, Punjab, India, and discovered that approximately 80% of isolates were resistant to chlortetracycline, tetracycline, oxytetracycline, and triple sulfas. Shivachandra et al ( 2004 ) found 100% resistance to sulfadiazine and widespread resistance to amikacin, carbenicillin, erythromycin, and penicillin in Pasteurella multocida isolates from chickens and other birds from 11 separate states in India.…”

Antibiotic susceptibility and production of extended-spectrum beta-lactamase (ESBL) of E. coli strains isolated from meat

“…Antimicrobials are used extensively in food animal production for disease prevention, treatment and growth promotion. Sarma et al (1981) discovered that approximately 80% of isolated E. coli from healthy and diseased poultry was resistant to chlortetracycline, tetracycline, oxytetracycline and triple sulfas. Similarly, Paula Signolfi et al (2019) found that more than 67% of isolated Escherichia coli were resistant to tetracycline, nalidixic acid and ampicillin.…”