Drooling in Parkinson's disease: A review

Srivanitchapoom, Prachaya; Pandey, Sanjay; Hallett, Mark

doi:10.1016/j.parkreldis.2014.08.013

Cited by 183 publications

(199 citation statements)

References 68 publications

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“…According to international literature, in spite of the small number of patients, our study concludes that therapeutic resource with Botulinum toxin A is an efficient treatment option for sialorrhea in patients with ALS and PD [33][34][35].…”

Section: Resultsmentioning

confidence: 68%

Efficacy of Incobotulinumtoxin Type A (Xeomin®) in the Management of Sialorrhea in Neurodegenerative Diseases

Marvulli¹,

Mastromauro²,

G³

et al. 2017

J Alzheimers Dis Parkinsonism

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Section: Resultsmentioning

confidence: 68%

Efficacy of Incobotulinumtoxin Type A (Xeomin®) in the Management of Sialorrhea in Neurodegenerative Diseases

Marvulli¹,

Mastromauro²,

G³

et al. 2017

J Alzheimers Dis Parkinsonism

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“…There are neither standard diagnostic criteria nor standard severity assessment tools for evaluating drooling in PD. In accordance with the possible pathophysiology, dopaminergic agents have been used to improve salivary clearance; however, these agents are not completely efective in drooling control [19].…”

Section: Speech Disorders In Parkinson Disease Results From the Disordermentioning

confidence: 99%

Speech Impairment, Phonation, Writing, Salivation, and Swallowing in Patients with Parkinson’s Disease

Savić¹

2017

Advances in Speech-Language Pathology

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Introduction Parkinson's disease (PD) can inluence the function of respiration, phonation and articulation, quality of speech, swallowing, salivation, and graphomotor skills. Aim and methodology:This chapter is based on research of the degree of impairments of speech, phonation, salivation, swallowing, and handwriting in 64 patients with PD. The results of maximal phonation time (MPT) were compared with two control groups of healthy young (N = 35) and healthy elderly (N = 35) subjects. The degree of impairment of these functions was measured by the Uniied Parkinson Disease Rating Scale (UPDRS) subtests. Results and discussion:In the group with PD, speech impairments of various degrees were present in 82.81% of patients. The problem of salivation control of diferent degrees was present in 68.75% of the sample. Swallowing diiculty of diferent degrees was present in 53.15% of the sample. Diiculty writing of various degrees had 84.38% of the sample. The average MPT in group with PD was 11.61 s, 21.39 s in the group of healthy young, and 20.52 in the group of healthy elderly subjects. Conclusion:Patients with PD on subtests UPDRS had various degrees of damages to the functions. Patients with PD had signiicantly shorter MPT than the control group.

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“…22 Parosmia, which is defined as distorted odor perception in the presence of an odor source, is a much less frequent non-motor sign in PD patients 23 . Drooling is defined as excessive pooling and spillover of saliva out of the oral cavity and is considered one of the most unpleasant non-motor symptoms by patients and caregivers 24 . The main factor that causes drooling in PD patients is impaired intra-oral salivary clearance 24 .…”

Section: Discussionmentioning

confidence: 99%

“…Drooling is defined as excessive pooling and spillover of saliva out of the oral cavity and is considered one of the most unpleasant non-motor symptoms by patients and caregivers 24 . The main factor that causes drooling in PD patients is impaired intra-oral salivary clearance 24 . Drooling is more common in PD patients in the advanced stages of the disease and is uncommon in the initial stages 24 .…”

Section: Discussionmentioning

confidence: 99%

Unusual motor and non-motor symptoms and signs in the early stage of Parkinson’s disease

Teive

Filho

Munhoz³

2016

Arq. Neuro-Psiquiatr.

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Objective Patients with Parkinson’s disease (PD) may present with unusual motor and non-motor symptoms and signs in the early stage of the disease. Methods Cases were collected over a five-year period at two tertiary movement disorders clinics. All had a diagnosis of PD with unusual presentations defined retrospectively as the presence of complaints not objectively related to any of the classic cardinal signs of parkinsonism or the typical early non-motor features of PD. Results A total of 15 early PD patients fulfilled the proposed criteria, presenting with symptoms such as atypical tremors, shoulder pain, signs related to the rigid akinetic syndrome, as well as cases of asthenia, rhinorrhea, parosmia, dysgeusia, nocturnal sialorrhea, and color discrimination disorders. Conclusions Unusual motor and non-motor symptoms and signs in the early stage of PD can be difficult to interpret. Specialists should be aware of these conditions as clues to a potential diagnosis.

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Drooling in Parkinson's disease: A review

Cited by 183 publications

References 68 publications

Efficacy of Incobotulinumtoxin Type A (Xeomin®) in the Management of Sialorrhea in Neurodegenerative Diseases

Efficacy of Incobotulinumtoxin Type A (Xeomin®) in the Management of Sialorrhea in Neurodegenerative Diseases

Speech Impairment, Phonation, Writing, Salivation, and Swallowing in Patients with Parkinson’s Disease

Unusual motor and non-motor symptoms and signs in the early stage of Parkinson’s disease

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