Drei Jahre Nachbeobachtung nach refraktiver Small Incision Lenticule Extraction (SMILE) mit einem 500-kHz-Femtosekundenlaser im „Fast Mode“

Abstract

The aim of this clinical trial was to check the results of laser built-in settings 3 years after ReLEx SMILE for moderate and high myopia in unselected "real life" patients. 50 myopic eyes of 27 patients were called in for examination after 3 years. 25 of these eyes with a preoperative myopia under - 6D comprised the "moderate myopia subgroup". All surgeries were performed with the 500 kHz VisuMax® femtosecond laser (Carl Zeiss Meditec AG, Jena) in the "fast mode" setting. The spherical equivalent (SE) of the entire group changed from - 6.18 D (± 1.91) prior to surgery to - 0.18 D (± 0.39) 3 years later. The preoperative SE in the moderate myopia subgroup changed from - 4.71 D (± 0.94) to - 0.04 D (± 0.23). 14 % of 50 eyes gained one line and 22 % lost one line of CDVA. The regression between month 3 and 36 was 0.07D for the entire group and 0.06 D for the moderate myopia subgroup. There were no late side effects. Primary undercorrection was predominantly seen in eyes over - 6 D. ReLEx SMILE shows remarkable stability over the entire range of myopias after 3 years, however primary undercorrection occurs predominantly in eyes of - 6.0 D, which necessitates nomogram adjustment.

Two‐years results of small‐incision lenticule extraction and wavefront‐guided laser in situ keratomileusis for Myopia

“…; Messerschmidt‐Roth et al. ), presumably because of the slightly lower myopic correction in this study. When comparing UDVA during the early postoperative period (particularly at 1 week postoperatively), we found that eyes treated with wavefront‐guided LASIK recovered faster than eyes treated with SMILE.…”

“…Messerschmidt‐Roth et al. () demonstrated that myopic regression between 3 and 36 months was −0.07 D. The data presented in a previous 5 ‐years study after SMILE (mean regression of −0.48 D) were comparable to those of other keratorefractive procedures (Blum et al. ).…”

“…Messerschmidt‐Roth et al. () and Pedersen et al. () reported that 78% of eyes were within ±0.5 D at the 3‐years follow‐up.…”

“…; Messerschmidt‐Roth et al. ) and one with a 5‐years follow‐up (Blum et al. ) are available in the peer‐reviewed literature available through a PubMed search as of November 2016.…”

“…() used a prototype of the 200‐kHz VisuMax femtosecond laser, whereas Messerschmidt‐Roth et al. () and Pedersen et al. () used the current 500‐kHz VisuMax technology, which were applied in our study.…”