Dragon's Blood extract has antithrombotic properties, affecting platelet aggregation functions and anticoagulation activities

The antithrombotic effect of RSNK in blood-stasis model rats

“…APTT is related to the intrinsic coagulation phase in plasma (Quinn et al, 2000). On the other hand, PT is used to evaluate the overall efficiency of extrinsic clotting pathway (Xin et al, 2011). TT and FIB are related to the third coagulation phase in plasma, and the prolongation of TT or the reduction of FIB indicates inhibition of thrombin-mediated fibrin formation (Leadley et al, 2000).…”

Meta-analysis of dragon’s blood resin extract as radio-protective agent

“…DBE has shown to have antithrombotic activity as it effects platelet aggregation and anticoagulation activities. Mice treated with ethanol extract A (EA) fraction of DB had less thrombus in lungs and cerebrums; EA had antithrombotic activity [15]. The primary effect was inhibition of platelet aggregation, by decreasing fibrinogen levels, increasing prothrombin time and activated partial thromboplastin time [46] (Figure 7).…”

“…DB is a potential therapeutic agent for neurodegenerative diseases [55] (Figure 10). Effect of dragons blood on pathological changes, blood hemorrhage, thrombotic and blood stasis in mice lungs [15]. Effect of EA and precipitate B in pathological photomicrograph of mice lung and cerebrum (a and d), mice treated with EA had less thrombus in lungs and cerebrums (b and e), mice treated with precipitate B showed serious pathological changes of hemorrhage and blood stasis in lungs (c and f) indicating that EA had positive antithrombotic effects in vivo [15].…”

HPLC-ESI-MS analysis of flavonoids obtained from tissue culture of Dracaena cambodiana

“…In China, it is used for the treatment of wounds, leucorrhea, fractures, diarrhea, as well as intestinal and stomach ulcers for a long time [3] . Phytochemical investigation has revealed that the main constituents of dragon's blood are flavonoids, which exhibit many pharmaceutical properties, such as haemostatic, analgesic, antimicrobial, antitumor, immunomodulatory, antiulcer, antidiarrhetic, anti-inflammatory [1] , wound healing [4] and anticoagulant activities [5,6] . Therefore, medicines based on dragon's blood have been developed tremendously.…”