Dr. N. Jacob and Dr. C.O. Jacob reply

Jacob, Noam; Jacob, Chaim O.

doi:10.3899/jrheum.101279

Cited by 3 publications

(6 citation statements)

References 6 publications

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“…Several ADs, including SSc, are characterized by a strong sex bias, with females being affected more frequently than males [4,8]. Very little is known about whether genes on the sex chromosomes can directly influence on susceptibility to SSc.…”

Section: Discussionmentioning

confidence: 99%

“…To date, very little is known about the possible association between the genes located on the sex chromosomes with their role in the immune system homeostasis and the susceptibility of the female sex to ADs [6,7]. Interestingly, recent reports have indicated that IRAK1 (Interleukin 1 Receptor Associated Kinase 1) gene, was the first X chromosome-linked gene associated with susceptibility and female predominance to systemic lupus erythematosus (SLE) [8] and rheumatoid arthritis (RA) [9]. IRAK1 is a serine/threonine protein kinase with significant role in TLR/IL-1 receptor (TIR) activation of NF-κB transcription factor, which subsequently increases the expression of many genes related to immunological functions [10][11][12].…”

mentioning

confidence: 99%

“…Altered activation of NF-κB represents the critical event in pathogenesis of some ADs, acting through aberrant transcriptional regulation of many proinflammatory mediators [13]. Since IRAK1 is considered to be the "on-switch" of TIR signaling complex, it is recognized as a risk gene in ADs [8,14].…”

mentioning

confidence: 99%

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Impact of alterations in X-linked IRAK1gene and miR-146a on susceptibility and clinical manifestations in patients with systemic sclerosis

et al. 2018

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Impact of alterations in X-linked IRAK1gene and miR-146a on susceptibility and clinical manifestations in patients with systemic sclerosis

et al. 2018

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“…'Doing dignity work': Indian security guards' interface with precariousness. Journal of Business Ethics, 162(3), 553-575.…”

Section: Defining the Social Compactmentioning

confidence: 99%

Social Compact: Co-creating Socially Responsible Businesses the Indian Way

Noronha

Jain²,

Puri³

et al. 2022

Vikalpa: The Journal for Decision Makers

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“…Teknologi kereta tercepat saat ini menggunakan teknologi Maglev (Magnetic Levitation) [2]- [7]. Relevansi penelitian ini dengan kebutuhan industri kereta api adalah untuk menunjang produsen kereta api nasional agar mampu membangun dan menguasai teknologi kereta cepat dengan teknologi Maglev.…”

Section: Pendahuluanunclassified

Karakteristik Medan Magnet Pada Kumparan Berinti Besi Sebagai Bahan Pembuatan Prototipe Kereta Maglev

Jamaludin¹,

Pradipta²

2019

JPI

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Prinsip kerja kereta maglev adalah adanya interaksi antar kutub – kutub magnet yang terdapat pada kereta dengan kutub – kutub magnet yang berada di sepanjang jalur kereta. Kutub – kutub magnet tersebut terbuat dari kumparan dengan kawat superkonduktor yang dialiri arus listrik. Secara teori besar medan magnet tergantung pada besar arus yang mengalir, inti kumparan dan jumlah belitan. Pada penelitian ini telah dibuat sebuah kumparan dengan inti besi berukuran panjang 5 cm dan diameter 8mm dengan jumlah belitan sebanyak 400 putaran. Pengujian karakteristik dilakukan dengan mengalirkan arus listrik searah pada kumparan dengan memvariasikan besaran arusnya. Pengukuran medan magnet dilakukan pada jarak tertentu antara 0 s.d 5 cm dengan rentang 0,5 cm dari ujung kumparan. Dihasilkan medan magnet paling besar berada pada jarak terdekat dengan kumparan dan paling kecil berada pada jarak terjauh dari kumparan yang tidak terkena pengaruh medan magnet. Jarak terjauh yang masih terpengaruh oleh medan magnet adalah antara 25 s.d 40 cm

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Dr. N. Jacob and Dr. C.O. Jacob reply

Cited by 3 publications

References 6 publications

Impact of alterations in X-linked IRAK1gene and miR-146a on susceptibility and clinical manifestations in patients with systemic sclerosis

Impact of alterations in X-linked IRAK1gene and miR-146a on susceptibility and clinical manifestations in patients with systemic sclerosis

Social Compact: Co-creating Socially Responsible Businesses the Indian Way

Karakteristik Medan Magnet Pada Kumparan Berinti Besi Sebagai Bahan Pembuatan Prototipe Kereta Maglev

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