2018
DOI: 10.1016/j.bbrc.2018.09.103
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Downregulated miR-1247-5p associates with poor prognosis and facilitates tumor cell growth via DVL1/Wnt/β-catenin signaling in breast cancer

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Cited by 34 publications
(21 citation statements)
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“…According to our study, mir-1247-5p could be a novel tumor suppressor and its lower expression was associated with malignant biological behavior and poor prognosis of breast cancer. In latest study, mir-1247-5p was down-regulated in breast cancer [9] and this is in accordance with our conclusion. Although it was a pity that we could not complete the functional assay in this study, we mentioned a variety of pathways which mir-1247-5p might be involved in section of discussion [10][11][12].…”
Section: Commentarysupporting
confidence: 90%
“…According to our study, mir-1247-5p could be a novel tumor suppressor and its lower expression was associated with malignant biological behavior and poor prognosis of breast cancer. In latest study, mir-1247-5p was down-regulated in breast cancer [9] and this is in accordance with our conclusion. Although it was a pity that we could not complete the functional assay in this study, we mentioned a variety of pathways which mir-1247-5p might be involved in section of discussion [10][11][12].…”
Section: Commentarysupporting
confidence: 90%
“…For instance, overexpression of miR-153 in prostate cancer can predicate the poor prognosis of patients (35). Downregulation of miR-1247-5p in breast cancer is associated with poor prognosis of patients (36). All the aforementioned findings of the present study, indicate that miR-623 participated in and suppressed the progression of breast cancer.…”
Section: Discussionsupporting
confidence: 63%
“…In addition, all patients participated in a 5-year follow-up survey for the collection of the survival information. Patients were followed-up at 6,9,12,15,18,21,24,30,36,42,48, and 60 months after surgery over the telephone.…”
Section: Methodsmentioning
confidence: 99%
“…In addition, several clinicopathological parameters have been introduced in BC management, including clinical stages, histological grade, histological type and lymph node metastasis (LNM). Nevertheless, some patients that possess the same clinicopathological features have different outcomes of prognosis [ 6 ]. Thus, novel treatment methods for BC are urgently needed.…”
Section: Introductionmentioning
confidence: 99%