2000
DOI: 10.1292/jvms.62.435
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Dose-related Cardiovascular Effects of Isoflurane in Chickens during Controlled Ventilation.

Abstract: ABSTRACT. We studied cardiovascular effects of isoflurane in chickens during controlled ventilation. Following the determination of the minimal anesthetic concentration from the response to clamping of a digit, dose-related effect of isoflurane on heart rate and arterial pressure were studied. The minimal anesthetic concentration of isoflurane was 1.25 ± 0.13% (mean ± SD, n=9). There was a dosedependent decrease in arterial pressure. The heart rate did not change significantly over a range of 1 to 2 times the … Show more

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Cited by 35 publications
(50 citation statements)
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References 11 publications
(30 reference statements)
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“…The MAC value, however, may vary considerably among avian species (Mercado and others 2008) and can be influenced by many physiological factors (body temperature, metabolic rate, blood CO 2 tension and large variations in blood pressure; Quasha and others 1980). In the current study, as in several other studies determining MAC values in birds (Ludders and others 1989, Naganobu and Hagio 2000, Naganobu and others 2003, Kim and others 2011, Escobar and others 2012, Phair and others 2012), body temperature remained stable during all the anaesthetic procedures. Consequently, body temperature was unlikely to have influenced these results.…”
Section: Discussionsupporting
confidence: 88%
“…The MAC value, however, may vary considerably among avian species (Mercado and others 2008) and can be influenced by many physiological factors (body temperature, metabolic rate, blood CO 2 tension and large variations in blood pressure; Quasha and others 1980). In the current study, as in several other studies determining MAC values in birds (Ludders and others 1989, Naganobu and Hagio 2000, Naganobu and others 2003, Kim and others 2011, Escobar and others 2012, Phair and others 2012), body temperature remained stable during all the anaesthetic procedures. Consequently, body temperature was unlikely to have influenced these results.…”
Section: Discussionsupporting
confidence: 88%
“…In the nematode, immobility represents complete lack of sinusoidal body movement. Data was obtained from the following sources: a: Crowder et al (1996), b: Friedman et al (2010, c: Tatara, Kamaya, and Ueda (2002), d: Mosley, Dyson, and Smith (2003), e: Bonath and Zschege (1979), f: Naganobu and Hagio (2000), g: Ludders, Mitchell, and Schaefer (1988), h: Ludders, Mitchell, and Rode (1990), i: Ludders (1992), j: Sonner et al (1999), k: White, Johnston, and Eger (1974), l: Drummond (1985), m: , n: Crout (1971), o: MacKenzie (1977), p: Tranquilli, Thurmon, and Benson (1985), q: Steffey, Howland, Giri, and Eger (1977), r: Tinker et al (1977), s: Mapleson (1996). monitoring their activity levels with infrared monitoring systems (Friedman et al, 2010). Originally designed to measure circadian rhythms in the fly (Hamblen et al, 1986), these activity-monitoring systems can in principle be used to study the effects of volatile anesthetics on mobility, as there is a strong correlation between loss of activity and immobility (Shaw, Cirelli, Greenspan, & Tononi, 2000).…”
Section: Volatile Anesthetics Produce Immobility At Different Concentmentioning
confidence: 99%
“…No presente estudo a diminuição da FC ocorreu após a indução e manutenção anestésica com o agente inalatório isoflurano. O isoflurano atua deprimindo o miocárdio e indiretamente é responsável pelo acúmulo de gás carbônico no organismo, que também é responsável pela depressão cardiovascular (Naganobu & Hagio 2000), resultando na diminuição da FC. Em relação à PAS é possível observar uma diminuição dos valores no momento M3 em relação ao momento basal no GT, não sendo observado nos demais tempos correspondentes ao estímulo cirúrgico.…”
Section: Resultsunclassified
“…Em relação à PAS é possível observar uma diminuição dos valores no momento M3 em relação ao momento basal no GT, não sendo observado nos demais tempos correspondentes ao estímulo cirúrgico. Curro, Brunson & Paul-Murphy (1994) explicam que a diminuição da PAS deve-se ao fato que os opioides totais aumentam o tônus vagal em aves de forma semelhante ao que acontece em mamíferos, levando as aves desenvolver bradicardia com diminuição indireta da PAS, além do efeito sinérgico com o isoflurano que também é responsável por esta diminuição através da sua atuação diretamente sobre a vasculatura periférica, diminuindo a resistência vascular sistêmica, através da vasodilatação (Naganobu & Hagio 2000). Valores semelhantes de PAS foram observados por Guimarães et al (2007), em pombos anestesiados com morfina e isoflurano.…”
Section: Resultsunclassified