Donor sperm recipients: fertility treatments, trends, and pregnancy outcomes

Abstract

Purpose To report fertility treatment use and outcomes among patients who use donor sperm for intrauterine insemination (IUI), in vitro fertilization (IVF), and reciprocal IVF (co-IVF). Methods This is a retrospective review of patients who used donor sperm at an urban, southeastern academic reproductive center between 2014 and 2020. Results Among the 374 patients presenting for care, 88 (23.5%) were single, 188 (50.3%) were in a same-sex female partnership, and 98 (26.2%) had a male partner with a diagnosis of male factor infertility. Most patients did not have infertility (73.2%). A total of 1106 cycles were completed, of which there were 931 IUI cycles, 146 traditional IVF cycles, and 31 co-IVF cycles. Live birth rates per cycle were 11% in IUI, 42% in IVF, and 61% in co-IVF. Of all resulting pregnancies, hypertensive disorders were most commonly experienced (18.0%), followed by preterm delivery (15.3%), neonatal complications (9.5%), gestational diabetes (4.8%), and fetal growth restriction (4.8%). Of the 198 infants born, fifteen (8.3%) required admission to the neonatal intensive care unit and three (1.7%) demised. Pregnancy and neonatal complications were more likely to occur in older patients and patients with elevated body mass index. Conclusion The use of donor sperm for fertility treatment is increasing. These data show reassuring live birth rates; however, they also highlight the risks of subsequent pregnancy complications. With the expansion of fertility treatment options for patients, these data assist provider counseling of patients regarding anticipated cycle success rates and possible pregnancy complications.

Lesbian shared IVF: the ROPA method: a systematic review

“…All these rates were higher compared with one-way IVF, but the authors did no statistical comparison. 47 …”

“…All these rates were higher compared with one-way IVF, but the authors did no statistical comparison. 47 The first comparative study published was a retrospective cohort based on 60 couples (and cycles) of ROPA and 120 cycles of IVF. No differences were found in the age of the ROPA donors, recipients, and women undergoing single parented IVF (around 34 years old), but the partners of the latter were significantly older (36.5 years old, P5.001).…”

Women’s Adherence to Healthy Dietary Patterns and Outcomes of Infertility Treatment

“…Results are presented as predicted marginal proportions and 95% CIs. Since success rates differ substantially between IUI and IVF cycles, analyses evaluating associations with clinical pregnancy and live birth were conducted separately for IUI and IVF cycles . However, since the probability of pregnancy loss is comparable in IUI and IVF cycles, analyses focused on pregnancy loss included analyses of IUI and IVF cycles separately as well as analyses combining both IUI and IVF cycles.…”