“…Negative pressure wound care products are also associated with an increase in factors accelerating wound healing such as: wound oxygenation, angiogenesis, and blood flow, granulation tissue formation (EWMA, 2008). Relative contraindications of the negative pressure wound care products are necrotic tissue formation with eschar on in the wound, priority of debridement requirement, presence of an untreated osteomyelitis around the wound, cancer in the wound or development of a fistula towards an organ or body cavity (Cooper and Young, 2000;Eryilmaz et al, 2015). When VAC (vacuum-assisted closure) treatment used as negative pressure wound care product is compared with standard gauze dressings, it is reported that VAC treatment further reduces the depth of chronic wounds, provides a faster recovery, causes fewer infections and allows shorter hospitalization (Joseph et al, 2000;Vuerstaek et al, 2006;Mouës et al, 2007).…”