Does coffee drinking have beneficial effects on bone health of Taiwanese adults? A longitudinal study

Abstract

BackgroundResults from studies investigating the association between coffee consumption and osteoporosis or bone mineral density (BMD) have been inconsistent. This longitudinal study was performed to assess the effect of coffee drinking on bone health of Taiwanese adults.MethodsData were retrieved from the Li-Shin (Landseed) Hospital in Taoyuan City. In 2006, 6152 participants completed a questionnaire on coffee drinking and other lifestyle factors. In 2014, 5077 of them were followed up. Nonetheless, a total of 2395 participants with incomplete data were excluded. The final analyses included 2682 participants comprising 1195 men and 1487 women (706 premenopausal and 781 postmenopausal). T-scores were derived from the osteo-sono assessment index (OSI) which is a surrogate of BMD. Coffee drinking was categorized as “no, medium, and high” based on the number of cups that were consumed per week in both 2006 and 2014.ResultsIn general, medium and high coffee drinking were associated with higher T-scores. However, significant results were observed only among high drinkers (β = 0.158; P = 0.0038). Nonetheless, the test for linear trend was significant (P = 0.0046). After stratification by sex, medium and high coffee drinking were associated with higher T-scores. However, significant results were prominent only among high male drinkers (β = 0.237; P = 0.0067) and the test for trend was significant (P = 0.0161). Based on menopausal status, coffee drinking was associated with higher T-scores. Nevertheless, significant results were found only among premenopausal women (β = 0.233; P = 0.0355 and β = 0.234; P = 0.0152 for medium and high coffee drinking, respectively. The test for linear trend was significant (P = 0.0108).ConclusionCoffee drinking was significantly associated with higher T-scores hence, a lower risk of osteoporosis in men and premenopausal women.Electronic supplementary materialThe online version of this article (10.1186/s12889-018-6168-0) contains supplementary material, which is available to authorized users.

Association between osteoporosis and menopause in relation to SOX6 rs297325 variant in Taiwanese women

“…Overweight and obesity were associated with a lower risk of osteoporosis in several studies. 1 , 11 , 13 , 45 - 48 Similar results were observed in our study. After stratification by the SOX6 rs297325 genotypes, these factors, however, remained significantly associated with osteoporosis only among those with the TC + CC genotype.…”

“…Age is an evident nonmodifiable primary risk factor for osteoporosis. 1 , 11 - 14 This was proven in this study as it remained significantly associated with an increased risk of osteoporosis regardless of the genotype. The capacity of the bone tissue to synthesize bone decreases as age increases.…”

“…BMD is a valuable clinical diagnostic index for osteoporosis and the best tool for osteoporotic fracture prediction. 7 - 10 Osteoporosis is associated with several genetic and nongenetic factors, 1 , 3 some of which include age, 1 , 11 - 14 sex, 1 - 3 menopausal status, 1 - 3 , 15 educational level, 11 , 12 , 14 , 16 coffee drinking, 11 smoking, 1 , 2 , 12 exercise, 1 , 2 , 12 alcohol consumption, 1 , 2 , 12 diet, 1 , 2 , 17 and body mass index (BMI). 1 , 11 , 13 , 14 , 18 …”

Endocrine Effects of Coffee Consumption

“…A recent study from the Taiwanese population examined the association between coffee consumption and T scores. The study revealed higher T scores in the coffee consumer group but half of the women in the study were premenopausal, so the evaluation of this study should be done carefully (32).…”

Does Drinking Coffee and Tea Affect Bone Metabolism in Patients with Inflammatory Bowel Diseases?

“…On the other hand, high and moderate intake of coffee correlated with a higher T-score. Researchers observed a trend in a group with moderate consumption, which may suggest the T-score increases as the consumption of coffee increases [ 53 ]. Additionally, there was no association between coffee intake and occurrence of fractures or femoral neck fractures in women, although intake of four and more cups of coffee per day decreased BMD by 2–4% when compared to the subjects consuming less than one cup of coffee per day [ 54 ].…”