Does Drinking Coffee and Tea Affect Bone Metabolism in Patients with Inflammatory Bowel Diseases?

Ratajczak, Alicja Ewa; Szymczak-Tomczak, Aleksandra; Zawada, Agnieszka; Rychter, Anna M.; Dobrowolska, Agnieszka; Krela‐Kaźmierczak, Iwona

doi:10.3390/nu13010216

Cited by 7 publications

(3 citation statements)

References 89 publications

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“…Caffeine can lead to osteoclastogenesis through the COX-2/prostaglandin E2 (PGE2) pathway [ 16 ]. Consumption of caffeine-containing products may affect the bone metabolism [ 17 ]. Since caffeine has various effects on the bone metabolism, it may affect the OTM as well, particularly if consumed on a daily basis [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Effect of Caffeine Injection on Orthodontic Tooth Movement in Rats: An Experimental Study on Rats

Golshah

Omidi

Nikkerdar

et al. 2022

International Journal of Dentistry

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Objectives. Several studies have investigated the effects of different medications on orthodontic tooth movement (OTM). This study assessed the effect of caffeine injection on OTM in rats. Materials and Methods. Thirty-five male Wistar rats were randomly divided into five groups. Their first molars and central incisors were attached with a nickel-titanium closed coil spring with 50 g load. The rats in the three experimental groups received 25, 50, and 75 mg/kg caffeine intraperitoneally for 21 days. The negative control group did not receive any injection and did not undergo orthodontic treatment. The positive control group underwent orthodontic treatment and received 0.9% NaCl (saline) injection. After 21 days, all rats were sacrificed by chloroform inhalation, and the maxilla was resected. The mean number of Howship’s lacunae, blood vessels, osteoclasts, and root resorption lacunae was histologically measured. The bone volume-to-total volume ratio (BV/TV) in maxillary molars was calculated by microcomputed tomography (micro-CT) to quantify bone loss. Results. The amount of OTM and the number of osteoclasts, blood vessels, and Howship’s lacunae significantly increased in rats under caffeine therapy, while the number of root resorption lacunae did not increase. Lower BV/TV in the caffeine groups was in accord with the increased count of osteoclasts. Conclusion. Caffeine injection can significantly increase OTM in rats.

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Section: Introductionmentioning

confidence: 99%

Effect of Caffeine Injection on Orthodontic Tooth Movement in Rats: An Experimental Study on Rats

Golshah

Omidi

Nikkerdar

et al. 2022

International Journal of Dentistry

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“…In addition, a report found that tea consumption after gastric cancer surgery could promote the recovery of postoperative gastrointestinal function and improve the quality of life of patients [13]. Meanwhile, tea consumption has been shown to improve cognition, mood, and human brain function [14] and somatic function [15]. All these studies show that drinking tea can improve the health condition of cancer patients.…”

Section: Introductionmentioning

confidence: 99%

Improvement of postoperative quality of life in patients with esophageal squamous cell carcinoma: does tea consumption have a role?

et al. 2022

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Background To investigate the effect of tea consumption on the improvement of postoperative quality of life in male patients with esophageal squamous cell carcinoma (ESCC). Methods The quality of life information of 290 male patients with ESCC was collected. The time to deterioration and the number of events in each area of quality of life was calculated by time-to-deterioration (TTD) model. The association between postoperative tea drinking and postoperative quality of life in male ESCC patients was investigated using the Cox proportional risk model. Results Postoperative tea-drinking patients experienced delayed TTD in multiple domains, including general health, physical, role, emotional, and cognitive function, fatigue, nausea and vomiting, dyspnea, loss of appetite, constipation, diarrhea, eating problems, difficulty swallowing, choking while swallowing saliva, dry mouth, taste difficulties, coughing, and speech problems. The multivariate Cox regression analysis showed that drinking tea after surgery improved quality of life, including physical function (HR = 0.722, 95% CI: 0.559-0.933), role function (HR = 0.740, 95% CI: 0.557-0.983), eating problems (HR = 0.718, 95% CI: 0.537-0.960), odynophagia (HR = 0.682, 95% CI: 0.492-0.945), trouble swallowing saliva (HR = 0.624, 95% CI: 0.444-0.877), coughing (HR = 0.627, 95% CI: 0.442-0.889) and speech problems (HR = 0.631, 95% CI: 0.441-0.903). Furthermore, the improvement was more significant in patients who drank tea before surgery and continued to drink tea after surgery. Conclusions Postoperative tea drinking had a positive effect on delay in clinical deterioration and improvements in multiple functions and symptoms associated with ESCC in men.

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“…On the other hand, a high consumption of caffeine may disturb the calcium-phosphate balance. Therefore, patients at risk of osteoporosis should consume a limited portion of tea [34,35].…”

Section: Introductionmentioning

confidence: 99%

Impact of Cigarette Smoking on the Risk of Osteoporosis in Inflammatory Bowel Diseases

Ratajczak

Szymczak-Tomczak

Rychter

et al. 2021

JCM

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Cigarette smoking constitutes one of the most important modifiable factors of osteoporosis, as well as contributes to an early death, tumors, and numerous chronic diseases. The group with an increased risk of a lower bone mineral density are patients suffering from inflammatory bowel diseases. In fact, tobacco smoke, which contains more than 7000 chemical compounds, affects bone mineral density (BMD) both directly and indirectly, as it has an impact on the RANK-RANKL-OPG pathway, intestinal microbiota composition, and calcium–phosphate balance. Constant cigarette use interferes with the production of protective mucus and inhibits the repair processes in the intestinal mucus. Nicotine as well as the other compounds of the cigarette smoke are important risk factors of the inflammatory bowel disease and osteoporosis. Additionally, cigarette smoking may decrease BMD in the IBD patients. Interestingly, it affects patients with Crohn’s disease and ulcerative colitis in different ways—on the one hand it protects against ulcerative colitis, whereas on the other it increases the risk of Crohn’s disease development. Nevertheless, all patients should be encouraged to cease smoking in order to decrease the risk of developing other disorders.

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Does Drinking Coffee and Tea Affect Bone Metabolism in Patients with Inflammatory Bowel Diseases?

Cited by 7 publications

References 89 publications

Effect of Caffeine Injection on Orthodontic Tooth Movement in Rats: An Experimental Study on Rats

Effect of Caffeine Injection on Orthodontic Tooth Movement in Rats: An Experimental Study on Rats

Improvement of postoperative quality of life in patients with esophageal squamous cell carcinoma: does tea consumption have a role?

Impact of Cigarette Smoking on the Risk of Osteoporosis in Inflammatory Bowel Diseases

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