Does Chorionic Villus Sampling Cause Fetomaternal Haemorrhage?

Warren, R.; Butler, Joan; Morsman, J. M.; McKenzie, C.; Rodeck, Charles H.

doi:10.1016/s0140-6736(85)91345-5

Cited by 50 publications

(20 citation statements)

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“…Out of the 44 infants with Rh-D HDFN 20 (45.5%) belonged to low risk, 13 Regarding blood product transfusion, 9 (20.5%) transfused packed red blood cells, 3 (6.8%) transfused platelet concentrate and 2 (4.5%) transfused fresh frozen plasma. Results of intensity of treatment was 20 (45.5%) belonged to grade 0, 13 (29.5%) to grade 1, 7 (15.9%) to grade 2, 3 (6.8%) grade 3 and 1 (2.3%) to grade 4 category of treatment.…”

Section: Amongmentioning

confidence: 99%

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CLINICAL CHARACTERISTICS AND MANAGEMENT OF Rh-D HAEMOLYTIC DISEASE OF NEWBORN

Vilambil¹,

Dharmadas²,

Usha³

et al. 2017

jemds

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BACKGROUNDIn Rh-D haemolytic disease of foetus and newborn (HDFN), newborns can be severely affected, thereby associated with extensive morbidity and mortality. Aim-The aim of this study is to describe the clinical profile of Rh-D HDFN. Settings and Design-This was a descriptive study conducted in newborn, who had Rh-D HDFN. Setting was Depts. of Transfusion Medicine and Paediatrics in Govt. Medical College, Trivandrum. MATERIALS AND METHODSEnrolment of newborn was done according to inclusion criteria. Maternal and neonatal details were noted and risk of jaundice, severity of disease and intensity of treatment was assessed. Statistical Analysis-All statistical data were analysed using SPSS software version 16. RESULTS 29 (65.9%) belonged to male gender and 15 (34.1%) to female gender. The mean bilirubin levels in neonates on Day 1, 2, 3, 4 and 5 were 4.15, 6.66, 9.44, 11.1 and 11.14 mg% respectively; 20 (45.5%) belonged to low risk, 13 (29.5%) to low intermediate risk, 7 (15.9%) to high intermediate risk and 4 (9.1%) to high risk categories; 4 (9.1%) belonged to no anaemia category, 17 (38.6%) belonged to mild anaemia category, 19 (43.2%) to moderate category and 4 (9.1%) to severe category; 35 (79.5%) of infants showed signs of haemolysis; 33 (75%), 7 (15.9%), 3 (6.8%) and 1 (2.3%) infants had mild, moderate, severe and very severe disease respectively; 20 (45.5%) infants required no treatment; 13 (29.5%) infants were treated only with phototherapy. IVIG was given along with phototherapy in 7 (15.9%) infants; 4 (9.1%) infants were treated with exchange transfusion along with IVIG and phototherapy. Neonates were transfused with 9 (20.5%) packed red blood cells, 3 (6.8%) platelets and 2 (4.5%) fresh frozen plasma. Results of intensity of treatment was 20 (45.5%) belonged to grade 0, 13 (29.5%) to grade 1 category; 7 (15.9%) fell into grade 2, 3 (6.8%) into grade 3 and 1 (2.3%) into grade 4 category of treatment. CONCLUSIONMale infants had higher risk of developing Rh-D HDFN. Majority of infants had mild hyperbilirubinaemia and anaemia only. Disease was mild among 3/4 th of infants and almost half of the infants required no treatment.

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Section: Amongmentioning

confidence: 99%

“…13 Walker et al noticed that the risk of stillbirth in a woman who previously delivered mildly affected infant was 2%, whereas in a woman who delivered one previous stillbirth was as high as 70%. 7 In this analysis, eleven mothers of infants with Rh-D HDFN had undergone postpartum RhIG prophylaxis during previous deliveries.…”

Section: Amongmentioning

confidence: 99%

CLINICAL CHARACTERISTICS AND MANAGEMENT OF Rh-D HAEMOLYTIC DISEASE OF NEWBORN

Vilambil¹,

Dharmadas²,

Usha³

et al. 2017

jemds

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“…A imunização prévia no sistema Rh também é outro fator para a contra-indicação da BVC porque, indubitavelmente, essa biópsia induz à mistura de sangue materno e fetal (Warren et al, 1985). Para casais com filhos anteriores portadores de malformações não devidas a alterações cromossômicas, mas para as quais há suspeita de que possa haver recorrência (por exemplo, malformações de membros, malformações cranianas, malformações múltiplas etc.)…”

Section: Contra-indicaçõesunclassified

Diagnóstico pré-natal

Júnior

2002

Ciênc. saúde coletiva

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“…CVS does not appear to alter the fetal growth potential (Williams et al 1987) nor does it induce changes in the fetal behavioural state (Boogert et al 1987). Based on serum AFP determinations, feto-maternal transfusion occurs in 50% of the patients as a result of the procedure (Warren et al 1985). However, no correlation has been found between the number of catheter insertions, gestational age at sampling, or milligrams of tissue sampled and the occurrence of feto-maternal haemorrhage (Warren et al 1985).…”

Section: Introductionmentioning

confidence: 99%

“…Based on serum AFP determinations, feto-maternal transfusion occurs in 50% of the patients as a result of the procedure (Warren et al 1985). However, no correlation has been found between the number of catheter insertions, gestational age at sampling, or milligrams of tissue sampled and the occurrence of feto-maternal haemorrhage (Warren et al 1985). The risk of spontaneous abortion after CVS has been evaluated by a number of investigators and is approximately 4% in experienced units (Jahoda et al 1985;Brambati et al 1987).…”

Section: Introductionmentioning

confidence: 99%

Uterine bloodflow velocity waveforms before and after transcervical chorionic villus sampling

Cohen–Overbeek

Jahoda

Wladimiroff

1990

Ultrasound in Medicine & Biology

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Abstract--Flow velocity waveforms from the left and right uterine artery were studied relative to transcervical chorionic villus sampling (CVS) between 9 and 11 weeks of gestation in 12 uncomplicated pregnancies and 5 pregnancies resulting in second trimester fetal loss. There was no significant difference in mean pulsatility index (PI) as a measure of downstream impedance, between the left and right uterine artery. There were also no significant changes in PI relative to the CVS procedure both in uncomplicated pregnancies and in pregnancies ending in second trimester fetal loss.

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Does Chorionic Villus Sampling Cause Fetomaternal Haemorrhage?

Cited by 50 publications

References 5 publications

CLINICAL CHARACTERISTICS AND MANAGEMENT OF Rh-D HAEMOLYTIC DISEASE OF NEWBORN

CLINICAL CHARACTERISTICS AND MANAGEMENT OF Rh-D HAEMOLYTIC DISEASE OF NEWBORN

Diagnóstico pré-natal

Uterine bloodflow velocity waveforms before and after transcervical chorionic villus sampling

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